Natural lifting with support for collagen production using liquid PCL injection formulation
GOURI
Point1The world's first liquid injection formulation of PCL (polycaprolactone), a material used in thread lifts
Point2It spreads naturally at the injection site and lifts the problem areas without any discomfort.
Point3Collagen booster improves skin texture, elasticity, firmness, and radiance
GOURI
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BIANCA CLINIC's unique initiatives
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Naturally lifts sagging skin and wrinkles!
A liquid, highly diffusible PCL injection formulation
GOURI is the world's first liquid PCL (polycaprolactone) formulation, developed in May 2021*. PCL is one of the ingredients used in the threads used in thread lifts. By penetrating the skin, it stimulates fibroblasts, strengthening skin tissue and supporting collagen production. It is suitable for addressing concerns such as loose, sagging skin, lack of elasticity, as well as hollows, wrinkles, and dark circles under the eyes.
Gouri is a liquid formulation with relatively high diffusion power. Because the formulation spreads naturally at the injection site, it is said to have little discomfort when the effects are felt. At Bianca, treatments can be performed on areas of concern on the face such as the forehead, under the eyes, cheeks, and around the mouth, as well as the neck, décolleté, elbows, and back of the hands.
Do you need forest bathing?
Recommended for:
I want my skin to be firm and shiny
I want to improve sagging
I’m worried about dark circles and fine lines.
I'm concerned about my skin's lack of elasticity
I want to achieve skin care and lift at the same time
For a natural lifting effect


Features
Characteristics
What is GOURI?
GOURI is the world's first collagen booster made primarily from liquid PCL (polycaprolactone). When injected, it stimulates collagen production in the skin, lifting and tightening areas of concern, improving firmness and radiance, and reducing the appearance of dimples and dark circles. It spreads quickly across the entire face upon injection, eliminating the need for multiple needle injections and leaving little to no lumpy skin after injection, as is common with other skin-boosting products.

Stimulates fibroblasts to produce new collagen in the skin
Gouri is a treatment that supports collagen production, but the formulation itself does not contain collagen. Injecting gouri stimulates fibroblasts, strengthening skin tissue and leading to a powerful increase in collagen in the skin. Rather than "feeling the effects immediately after injection," the treatment gradually increases skin thickness and elasticity over the course of about a month, aiming for a lifting effect.
The formulation itself spreads quickly after injection, but it takes a relatively long time to break down, so the support for collagen production continues for a long time. Gouri's unique feature is that it naturally increases skin volume over the course of about a month after treatment, and the effects are said to last for several months.

Lower risk and higher safety compared to conventional injectable formulations
Conventional injectable formulations can cause side effects such as granulation formation and embolism caused by microparticles blocking blood vessels. However, Gouri is liquid and has high diffusibility, so these risks are reduced and it can be injected to address concerns in any part of the face.
Gouri underwent safety testing by North American Science Associates (NAMSA) in 2018, underwent Korean clinical trials for KFDA* approval, and obtained CE marking* in 2021. These certifications are also a source of reassurance.
* KFDA: The former name of the Ministry of Food & Drug Safety (MFDS), also known as the Korea Food and Drug Administration.
* CE marking: This mark indicates that a product meets the essential requirements of each directive, which stipulates the health and safety protection of users, in accordance with the European legislation known as the New Approach Directives established by the European Commission (EC).







Benefit
Merit
Merit.1
Achieve a natural lifting effect
Gouri is a treatment that gradually takes about a month to show results after injection, so it is popular with those who value natural, effortless changes.
Merit.2
No need to repeatedly insert needles
Because it is a liquid, it spreads quickly over the entire face after injection, and one of its attractions is that there is no need to insert needles multiple times.
Merit.3
Promotes collagen production for long-lasting results
Because gouri takes a relatively long time to break down inside the skin, it is expected that the lifting effect, firmness, and radiance brought by collagen production will last for several months.
Price list
Price list
Advice from Doctor BIANCA
Advice
■Feel the change with an injection of 2cc or more
To fully experience the skin changes and effects of Gouri, we recommend injecting a formulation of 2cc or more. Because Gouri itself does not contain collagen, rather than seeing visible changes immediately after the treatment, the treatment aims to slowly and naturally achieve skin elasticity and a lifting effect over the course of one month after injection. While the degree and duration of effects vary from person to person, Bianca recommends three treatments every three months. After that, we will decide whether to resume treatment after one year has passed and consult with a doctor, so please consult us each time.
■Not only on the face, but also on the décolleté, elbows, and backs of the hands
Gouri is expected to be more effective on skin that has lost firmness and become more saggy due to years of irritation and UV rays, rather than on skin that has experienced significant volume loss, and on skin that is concerned with "etched wrinkles" that deepen with age. Liquid PCL spreads quickly and promotes collagen production, improving skin firmness, radiance, and elasticity, and addressing looseness, sagging, wrinkles, and roughness. Gouri can also be injected into areas other than the face, such as the décolleté, which shows signs of aging, or the elbows and backs of the hands, where roughness is a concern.
■Dermapen 4 injection is an ideal approach for pores and crater-like acne scars
Our clinic also offers Gouri injections using the Dermapen 4. The Dermapen 4 is a pen-shaped device with 16 ultra-fine needles at its tip, which creates tiny holes in the skin, activating its natural healing powers. Using Gouri in conjunction with the Dermapen 4 makes it easier to deliver beauty ingredients to the dermis. By micro-stimulating the dermis with the needles, skin cells are activated, supporting the production of collagen and elastin, which provide elasticity to the skin. Even damaged skin that has traditionally been difficult to treat, such as enlarged pores and crater-like acne scars, can be expected to gradually lead to plumper, more youthful skin.
Flow of treatment
Content of treatment
01 Doctor's examination/counseling
We will listen to your concerns and propose a Gouri treatment plan. The treatment includes local anesthesia, but we can also provide nitrous oxide anesthesia for an additional fee, so please consult us if you are worried about pain.

02 Make-up removal and anesthesia
Before the treatment, you will be asked to cleanse and wash your face, and local anesthesia will be administered to the treatment area.

03 Treatment
Once the anesthesia has taken effect, gouri will be injected. The treatment time will depend on the area and scope of the treatment, but it will take about 30 minutes to complete.

we also focus on minimizing downtime for treatments.
Downtime
At Bianca Clinic, we strive to reduce pain and downtime, and have taken great care to ensure that even those who are sensitive to pain can receive treatment with peace of mind, by providing anesthesia assistance and selecting needles that are designed to reduce pain and internal bleeding.
Frequently Asked Questions Q&A・Notes
Q&A
[Treatment content] GOURI
[Estimated treatment period and number of sessions] Three sessions every three months, then treatment can be resumed one year later after further examination. *Depending on the condition.
[Cost] 110,000 yen per tooth *This treatment is an elective treatment (not covered by insurance).
There is an additional microcannula fee of ¥2,420 per area and a treatment fee of ¥24,200.
[Risks/Side Effects] Redness, swelling, edema, internal bleeding, hives, swelling, itching, etc.
[Caution regarding unapproved drugs]
・This treatment may involve the use of unapproved pharmaceuticals that have not been approved by the Ministry of Health, Labor and Welfare in Japan.
・Medicines used in treatments are imported by individuals under the doctor's discretion. For details, please refer to the Ministry of Health, Labor and Welfare's "Information on medicines and other items that require caution when imported by individuals."
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have received pharmaceutical approval, there may be no other domestically approved drugs containing the same ingredients.
・Information related to safety in other countries
- "GOURI" has been approved with the European CE mark.
-Serious risks or side effects may not be known.
・In the unlikely event that serious side effects occur, you may not be covered by the national Pharmaceutical Adverse Reaction Relief System.
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