Treat wrinkles and sagging skin with the power of regenerative medicine by injecting your own cells from when you were younger!
Dermal fibroblast therapy (Fibroblasts)
Point1Fibroblast cells, which decrease with age, are cultured and transplanted to produce new collagen.
Point2Restores firmness to skin that is concerned with signs of aging such as wrinkles and sagging
Point3The cultured skin cells are frozen and stored, allowing them to be transplanted periodically for decades to come.
Fibroblasts
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What is dermal fibroblast therapy?
BIANCA CLINIC offers a wide range of injection treatments that lead to beautiful skin with minimal downtime, and also focuses on regenerative medicine. Dermal fibroblast therapy (Fibroblasts) is a groundbreaking treatment that allows you to transplant skin cells from your youth into problem areas even after years or decades have passed.
The skin cells and blood collected from the patient's skin are frozen and stored under strict quality control at the Cell Bank Co., Ltd. (facility number: FA3150017), a cell culture center approved by the Ministry of Health, Labor and Welfare. The cells remain young and healthy almost permanently. For example, it is possible to withdraw skin cells from a stem cell bank at the age of 30, like a deposit, and transplant them into the skin of a 45-year-old.
In order to carry out regenerative medicine, including dermal fibroblast therapy, you must pass a rigorous screening by the Ministry of Health, Labor and Welfare's Specific Certified Regenerative Medicine Committee and submit a "Regenerative Medicine Provision Plan" to the local bureau of health and welfare. Our clinic has submitted a "Type 3200157 Regenerative Medicine Provision Plan," which is required for the implementation of regenerative medicine using the patient's own cells. We are a medical facility that has been officially approved by the Ministry of Health, Labor and Welfare and has obtained a plan number (PBXNUMX). Why not start maintaining your skin to maintain its natural beauty with the doctors at Bianca Clinic, who are well versed in skin treatment?
Case introduction
Cases
Cases.1
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Treatment name
Dermal fibroblast therapy
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Our Treatments
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Movie
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Recommended for:
Those who want to improve wrinkles around the eyes and mouth
Those who want to eliminate sagging skin on the face
Those who are worried about acne scars
Those who are concerned about aging of the neck and hands
Those who want a naturally youthful appearance
Those who are reluctant to inject foreign objects
Features
Characteristics
What is dermal fibroblast therapy (Fibroblasts)?
Dermal fibroblast therapy is a regenerative medical treatment for the skin in which dermal fibroblasts (skin cells), which produce the collagen, elastin, and hyaluronic acid that make up the skin, are collected from behind the ear, cultured and multiplied, and then injected into the area of concern with a syringe. Dermal fibroblasts, which play an important role in maintaining the moisture and firmness of the skin, decrease after the age of 20, and are said to be reduced to about one-third by the age of 50. By injecting skin cells into areas where wrinkles and sagging have occurred, it is expected that the skin's functions themselves will be affected and that this will help improve skin problems.
Skin cells that have been cultured at the Cell Culture Center and multiplied to 4,000 to 1 million cells can be stored semi-permanently. By collecting and multiplying your own skin cells while you are still young, you will be able to deal with skin problems that may occur several years or even decades down the line.
Dermal fibroblast therapy to slow down the speed of skin aging
Due to aging and stress, our skin cells decrease year by year and their function declines.
Dermal fibroblast therapy is a type of regenerative medicine that aims to restore skin to its original healthy state by supplementing skin cells that are losing firmness. The action of skin cells that produce collagen, elastin, and hyaluronic acid can be expected to be effective against aging symptoms such as improving wrinkles and sagging, and restoring firmness and elasticity. In addition, by continuing to inject regularly, it is possible to slow the progression of aging compared to skin that does not undergo any treatment. It is attracting attention as a new option for skin treatment that approaches future skin aging and maintains a youthful appearance.
After treatment, it takes about 3 months for the effects on the skin to appear.
The process in which the effects of dermal fibroblast therapy begin to appear before and after treatment is as follows:
[Before treatment] Skin showing signs of aging
As we age, the number of skin cells decreases and their function declines, causing the dermis to become thin and fragile. This condition causes aging symptoms such as wrinkles and sagging skin.
[Treatment] Transplant dermal fibroblasts
Healthy skin cells are harvested from the skin, cultured to 4,000 to 1 million cells, and then transplanted into the problem area. The collagen, hyaluronic acid, and elastin produced by the skin cells help repair skin tissue.
[From 3 months after treatment] Changes in the skin begin to appear
By accumulating new collagen, hyaluronic acid, and elastin inside the skin, symptoms such as wrinkles and sagging are reduced, and the skin is expected to become firmer and more elastic. Although it varies from person to person, some people report that their skin looks younger 3 to 12 months after the treatment.
Benefit
Merit
Merit.1
Natural and long-lasting effects
This is a skin regenerative medicine that transplants young, healthy skin cells. It lasts longer than other injection treatments and has the potential to produce a more natural look.
Merit.2
Regular use slows down skin aging
Continuing the treatment will slow down the rate of skin aging compared to skin that has not undergone any treatment, and will help maintain the firmness of your skin like when you were younger.
Merit.3
Almost no downtime
You can apply makeup and take a bath the day after treatment. Because your own cells are used, there is a low risk of allergies, and this treatment method is designed to be gentle on the body.
Treatment site
Treatment Area
Face, neck, and hands/fibroblast cells are collected from behind the ears
Price list
Price list
Advice from Doctor BIANCA
Advice
■What is the difference between Botox injections and hyaluronic acid injections?
Injection treatments include the use of preparations manufactured to address wrinkles and sagging skin, such as hyaluronic acid injections and Botox injections. In contrast, dermal fibroblast therapy involves extracting and cultivating the patient's own skin cells, which means that there is a low risk of side effects such as allergies.
Hyaluronic acid injections and Botox injections are the most likely to produce immediate results, but as they are eventually absorbed into the body, the effects are temporary. On the other hand, dermal fibroblast therapy restores the skin's functions, so long-term changes can be expected and it is said that there is no need to repeat the treatment frequently. If new skin problems arise after 5 or 15 years, you can have the injections again to maintain a stable, youthful appearance.
■A versatile treatment for problems on the face, neck, and hands
Dermal fibroblast therapy is suitable for areas around the eyes (corners of the eyes, eyelids, dark circles under the eyes, and nasolabial folds), around the mouth (nasolabial folds, marionette lines, and lips), the forehead, between the eyebrows, and cheeks. It can be used to treat any part of the face in detail. It can also be injected into the neck and hands, areas that are prone to showing signs of aging. When a problem arises, you can effectively deal with it by injecting the stored skin cells as needed.
Bianca Clinic has a track record of providing intricate designs with numerous injection treatments under the theme of "refined beauty." Even in re-injections of dermal fibroblast therapy, we perform treatments to maintain a natural youthful look while looking at the overall balance of each patient's face. We will support you for a long time, providing support for symptoms and concerns that appear as you age.
■For those who want a naturally youthful look
Dermal fibroblast therapy is a notable regenerative medicine that can address age-related concerns by cultivating and growing dermal fibroblasts taken from one's own skin and injecting healthy skin cells into the skin. It is chosen by those who want to treat aging symptoms such as nasolabial folds and wrinkles by revitalizing the skin at the cellular level. You can expect natural changes while still maintaining your individuality.
The time it takes for the effects to appear varies from person to person, but generally, skin cells gradually become more active within 3 to 12 months of treatment, and skin tends to become firmer and more lustrous. Unlike injection treatments that use pharmaceuticals, regenerative medicine is characterized by the ability to increase the number of your own skin cells. If you are interested in regenerative medicine for the skin, which helps restore youthfulness from within, please feel free to contact us.
Flow of treatment
Content of treatment
01 Medical examination and counseling by a doctor
Please tell the doctor about the area and symptoms that are bothering you. We will answer any questions or concerns you may have about the treatment.
02 Blood tests, skin samples, blood samples
To culture the cells, a rice-grain-sized piece of skin is taken from behind the ear, and blood is also taken to be used as the culture medium (the environment for culturing the skin cells).
The cell culture technicians at the Cell Culture Center will take responsibility for culturing and multiplying the skin cells by 1 times over a period of about five weeks. The cells not used for transplantation can be frozen and stored in specialized facilities.
03 Skin cell transplant (1st time)
The first skin cell transplant will be performed within 1 weeks to 5 months from the date of skin collection.
04 Skin cell transplant (2st time)
We recommend that you undergo the second transplant within about two weeks of the first transplant, as this allows for a higher rate of skin cell adhesion.
05 Skin cell transplant (3st time)
Since the frozen skin cells can be stored semi-permanently at a specialized institution, you can transplant them to the areas of concern at your own convenience, such as one to two years from the third time onwards. As a regular maintenance treatment, you can receive transplants of young skin cells from the time the skin was harvested for several years or decades. (The amount of skin cells stored will vary depending on the plan.)
we also focus on minimizing downtime for treatments.
Downtime
*Swelling, redness, and internal bleeding may occur, but will disappear within 1-2 weeks. Rarely, a lump may appear.
*After transplantation, it takes about one to six months for the skin cells to settle in the skin and repair the skin tissue.
*If you are using anticoagulants or antiallergic drugs, please inform your doctor in advance.
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Frequently Asked Questions Q&A・Notes
Q&A
[Treatment details] A treatment in which your own skin cells (dermal fibroblasts) are collected from behind the ear, cultured and multiplied in a specialized facility, and the multiplied skin cells are then transplanted onto the face, neck, hands, etc.
[Estimated treatment period and frequency] The first injection will be given 5 weeks after the skin and blood are collected, and the second injection will be given another 1 weeks later.
[Cost] ¥1,760,000 to ¥3,080,000 (including blood test fee, two transplants, and technical fee)
[Risks/Side Effects, etc.] Swelling, redness, internal bleeding, lumps, etc.
[Caution regarding unapproved devices and medicines]
・This treatment includes medicines that are not approved in Japan or treatments that have a different purpose than that approved by the Ministry of Health, Labor and Welfare.
- Medicines and medical equipment used in treatment are imported by individuals at the discretion of our clinic's doctors.
・Please refer to the following for information regarding medicines and other items that you should be careful of when importing for personal use.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
- Except for products that have received pharmaceutical approval, there are no other domestically approved drugs or medical devices with the same ingredients or performance.
・Information related to safety in other countries
- Serious risks or side effects may not be known.
・In the unlikely event that serious side effects occur, you will not be covered by the national pharmaceutical adverse reaction relief system.
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