For fatigue and signs of aging. Regenerative medicine that achieves beauty and health
Purified Concentrated Stem Cell Culture Supernatant Liquid Infusion (Stem Therapy)
Point1Approaching signs of aging such as age spots and lack of firmness through infusion therapy
Point2Invigorate cells from the inside of your body with concentrated infusions of domestically produced stem cell-derived ingredients
Point3Complete care for the whole body, from beauty to health management
Stem Therapy
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BIANCA CLINIC's unique initiatives
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Choose from a variety of infusion options to suit your concerns. We also offer a wide range of regenerative treatments.
What is Purified Concentrated Stem Cell Culture Supernatant?
Aging is beginning to be considered a treatable disease, and interest in regenerative medicine is on the rise even in the field of aesthetic medicine. BIANCA CLINIC offers a wide range of regenerative medicine treatments, including PRP injections using high-concentration platelets derived from the patient's own blood, and infusions and local injections of exosomes to promote tissue repair. Bianca Clinic employs doctors well versed in anti-aging (rejuvenation) medicine, and will assess the condition of each patient and provide the ideal anti-aging care according to their age.
We also offer infusion therapies to improve your health from the inside out, such as high-concentration vitamin C infusion (high-concentration vitamin infusion), NMN infusion therapy, NAD+ infusion therapy, and BIANCA DRIP (hydrogen therapy). If you are concerned about a particular treatment or are unsure which treatment is right for your problem, our doctors will suggest the most suitable treatment through counseling, so please feel free to consult with us at Bianca Clinic.
Do you need forest bathing?
Recommended for:
Those who want to improve skin problems
Those who want to prevent skin problems
Those who want to improve spots and freckles
Those who want to improve acne and scars
Those who want to regain firm, youthful skin


Features
Characteristics
What is purified and concentrated stem cell culture supernatant infusion?

Purified and concentrated cell culture supernatant drip is a regenerative medicine in which the supernatant obtained when culturing stem cells taken from humans is purified and concentrated, and then administered into the body. It is expected to approach aging and damaged cells and increase the body's natural ability to recover.
The purified and concentrated cell culture supernatant contains fewer harmful substances and is richer in growth factors than conventional stem cell culture fluid. The formulations used at our clinic are made without using any animal-derived ingredients in the manufacturing process, and are made from purified, concentrated ingredients only from humans. They are purified, concentrated, and refined while taking into consideration quality and safety, so that they contain high concentrations of growth factors while removing as many impurities as possible, such as ammonia released by cells.
Treatment to regenerate aged cells and damaged tissues
Purified and concentrated cell culture supernatant is the supernatant obtained during the stem cell cultivation process. This supernatant is rich in various humoral factors, including growth factors, immune regulators, anti-inflammatory factors, and nerve regeneration factors. It is believed that these factors promote the activity of cells weakened by aging or damage, and help repair and regenerate tissues. Therefore, purified and concentrated cell culture supernatant drip is a regenerative medicine that can be expected to enhance the regenerative power of cells and maintain beauty and health.
[What are stem cells?]
Stem cells are special cells that have the ability (pluripotency) to differentiate into cells that form various tissues such as skin, blood vessels, and bones, and are involved in tissue regeneration and repair. Stem cells are classified into embryonic stem cells (ES cells), adult stem cells, iPS cells (induced pluripotent stem cells), etc. based on their origin and capabilities. Stem cells decrease with age, and it is said that they may affect changes such as wrinkles and sagging.

Major growth factors in purified and concentrated stem cell culture supernatant
There are about 800 kinds of cytokines in the body, and they play various roles such as cell proliferation in skin and muscles, hair growth promotion, and inflammation suppression. Growth factors, which are a type of cytokine, are important components that are expected to be highly effective in the fields of beauty and regenerative medicine. In particular, HGF*, which is said to promote angiogenesis and tissue repair, is a noteworthy growth factor among stem cell culture supernatants. At Bianca Clinic, we carefully select a formulation with a high content of HGF and provide it as purified and concentrated stem cell culture supernatant infusion.
*HGF: Hepatocyte growth factor

[Characteristics of major growth factors]
aFGF: Stimulates fibroblasts, and is expected to have wound healing, wrinkle improvement, and whitening effects.
EGF: Promotes skin turnover and improves blemishes and dullness
IGF-1: Helps regenerate skin cells and improves firmness and elasticity
HGF: Promotes angiogenesis and tissue repair
TGF-β: Suppresses inflammation and improves sensitive skin conditions
PDGF: Stimulates cells responsible for tissue repair and promotes cell division
VEGF: Supports blood vessel formation
KFG: Acts on hair matrix cells to promote hair growth and regrowth
bFGF: Activates blood vessels, muscles, and skin cells, and is also involved in the regeneration of nerves and bones.
*We do not guarantee the effectiveness of our hospital's purified and concentrated stem cell culture supernatant infusion.







Benefit
Merit
Merit.1
Aim for beautiful skin with fewer problems
By promoting collagen production and suppressing inflammation, it addresses dullness and lack of firmness that comes with aging, leading to skin that is less prone to irritation.
Merit.2
Aging care for the whole body through infusion
By supplementing with growth factors, this treatment focuses on repairing and regenerating aged cells and damaged tissues, and works on signs of aging from within the body.
Merit.3
Supports health by relieving fatigue and improving immunity
It aids in energy metabolism and improves daily condition, helping to reduce fatigue and improve physical condition, supporting a healthy lifestyle.
Treatment site
Treatment Area
An IV is administered through a vein in the arm.
Price list
Price list
Advice from Doctor BIANCA
Advice
■Achieve a youthful and healthy body with infusion formulations made in Japan

When it comes to infusion therapy, some people may be concerned about the safety of the formulation that is directly administered into the body. Bianca Clinic uses purified and concentrated stem cell culture supernatant for infusion, which is derived from humans and is only from Japanese female donors. No animal-derived ingredients are used in the manufacturing process. Furthermore, as it is an infusion formulation produced domestically, it is also suitable for those who are particular about ingredients.
In addition to the purified and concentrated stem cell culture supernatant drip infusion, the preparations handled by Bianca Clinic are carefully selected by the doctors themselves, and are made from products that they would want to use themselves. Bianca Clinic is committed to health and beauty, and this regenerative medicine can only be provided by Bianca Clinic, which is committed to health and beauty, and will help you live a healthier and more positive life by addressing age-related concerns.
■Regenerative medicine other than purified concentrated stem cell culture supernatant drip
The purified and concentrated stem cell culture supernatant drip infusion, which can be used on the whole body, is a regenerative medicine suitable for those who want to take total care of their health and skin. Furthermore, for those who want to pinpoint a specific problem, we also offer site-specific regenerative medicine.
For example, if you have concerns about enlarged pores, acne scars, wrinkles, or sagging skin due to aging, you can choose the exosome facial. Exosome facial is a treatment that uses a derma pen to create tiny holes in the skin and apply exosomes that promote skin regeneration. In addition, Bianca Clinic also offers the Van-Ear facial, which uses high-concentration PRP (platelet-rich plasma) derived from autologous blood.
Our doctors will propose the most suitable regenerative medical treatment for each patient based on their concerns and requests. We also provide cosmetic medicine outpatient services, so please feel free to contact us with any questions you may have about your physical condition or treatment.
Flow of treatment
Content of treatment
01 Counseling/examination
When administering purified and concentrated stem cell culture supernatant infusion, the doctor will explain the details of the treatment, the risks, the expected effects, etc. During counseling, the doctor will ask about the patient's concerns and requests, and will decide whether purified and concentrated stem cell culture supernatant infusion is appropriate for the patient before proceeding with treatment.

02 Treatment (infusion)
The purified and concentrated stem cell culture supernatant will be administered intravenously into either the left or right arm. The infusion will take approximately 30 minutes. Please relax during the procedure. *You can expect results after just one treatment, but continuing the treatment will help you maintain your health and prevent aging.

03 Finish
After your treatment, please rest for a while. You can go home after the infusion is finished. On the day after your treatment, please make sure to drink plenty of fluids and pay attention to any changes in your physical condition.

we also focus on minimizing downtime for treatments.
Downtime
Frequently Asked Questions Q&A・Notes
Q&A
[Treatment details] A treatment in which the supernatant fluid obtained during stem cell cultivation is purified and concentrated, and then administered directly into the body via intravenous drip.
[Estimated treatment period and frequency] Approximately once every 2 weeks to once a month *Depending on the condition.
[Cost] Intravenous drip ¥60,258
[Risks/Side Effects] Internal bleeding, redness, etc. for 1-2 weeks
[Caution regarding unapproved devices and medicines]
・This treatment includes medicines that are not approved in Japan or treatments that have a different purpose than that approved by the Ministry of Health, Labor and Welfare.
- Medicines and medical equipment used in treatment are imported by individuals at the discretion of our clinic's doctors.
・Please refer to the following for information regarding medicines and other items that you should be careful of when importing for personal use.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
- Except for products that have received pharmaceutical approval, there are no other domestically approved drugs or medical devices with the same ingredients or performance.
・Information related to safety in other countries
- Serious risks or side effects may not be known.
・In the unlikely event that serious side effects occur, you will not be covered by the national pharmaceutical adverse reaction relief system.
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