column (e.g. in newspaper)
2024.07.27
Must Botox be Allergan brand!? Which formulations are less likely to trigger antibody production? Dr. Senki Akashi of Bianca Clinic explains!
With deep medical insight cultivated as an internal medicine specialist, I bridge aesthetic surgery, dermatology, and internal medicine. Having spent my childhood in China, I communicate fluently in Japanese, Chinese, English, and Korean. Possessing an international perspective—evidenced by invitations to present at overseas conferences—I actively promote techniques as a Key Opinion Leader (KOL) for GOURI and REJURAN®. My specialty procedures include double eyelid surgery, skin-nurturing boosters, and body hyaluronic acid treatments. My approach leverages the holistic understanding of the body cultivated through internal medicine to guide patients toward natural, healthy beauty.
Good evening, I'm Senki Akashi from BIANCA CLINIC.
Today I'll be answering some questions I often get on Instagram!
"Is Botox really only good if it's Allergan?"
"Which Botox formulation is less likely to trigger antibody formation?"
Let me give you a comprehensive explanation of this intriguing topic.
BIANCA Akashi Senki, MD Profile
Spent childhood in China and is trilingual in Chinese, Korean, and Japanese. After graduating from Nagoya University School of Medicine, she specialized in internal medicine with a focus on diabetes and endocrinology, becoming a board-certified internist. Subsequently, she gained experience performing over 5,000 surgical procedures and injectable treatments at a major cosmetic surgery clinic, later serving as director of a clinic in central Tokyo. She specializes in eye area surgeries, particularly double eyelid suture procedures and dark circle treatments. Currently at BIANCA Clinic, he supports patients in achieving a naturally beautiful glow from the inside out, encompassing all aspects of cosmetic surgery, medical aesthetics, and cosmetic dermatology.
＜Professional Affiliations and Qualifications＞
・Japanese Society of Internal Medicine Board-Certified Internist
・Japanese Diabetes Society
・Japanese Society of Aesthetic Plastic Surgery
・Japanese Society of Anti-Aging Medicine
＜Check out more information about Dr. Akashi Senki's Aesthetic Medicine here＞
Dr. Akashi Senki's Instagram account isHere
The official Instagram account for BIANCA isHere
The official YouTube account for BIANCA isHere
What exactly is "Botox"?
Actually, "Botox" is a brand name, and the generic name isBotulinum toxinIt is called.
Allergan (U.S.)'s formulation "BOTOX Vista®️Since "Botox" is well-known and has become established as a brand name, I'll use "Botox" in this blog for clarity.
The Relationship Between Botox and "Antibodies"
Botox antibodies, strictly speaking,neutralizing antibodies produced against impure proteins contained in the drugThat is the case.
Once antibodies develop, the medication becomes less effective, soMinimize impure proteins as much as possibleis important.
Features of Allergan's Botox
Here are the features of Allergan's Botox® formulation!
-
FDA (U.S. Food and Drug Administration) approved
-
Low in impure proteins
-
Thorough cold chain managementand the temperature is maintained at a constant level during transport
The bottleneck is stillPriceDue to its high cost, it falls into the "high-priced category among Botox treatments" at most clinics.
What Botox brands other than Allergan are less likely to trigger antibody formation?
So, are there other Botox products that offer good quality and cost-effectiveness?
Here are some representative examples.
CORETOX®️ (Korea / MEDYTOX)
-
Removing unnecessary complex proteins → Reduces antibody formation
-
The company's "Inotox" is a liquid formulation with minimal dissolution variation, ensuring consistent efficacy.
Bocor Chair (formerly Zeomin / Merz AG, Germany)
-
Impurities are said to be less than one-tenth of those in Argan oil.
-
Can be stored at room temperaturewith low risk during transport
Bianca Clinic offers CoreTox among these treatments.
Comparing the Differences Between Botox Products!
| Product Name | Country of Manufacture/Company | Features | Antibody Risk | Disadvantages |
|---|---|---|---|---|
| Allagan | United States/Allergan | FDA-approved cold chain transportation | extremely low | expensive |
| Core Tox | South Korea/MEDYTOX | Complex Protein Removal | low | Not approved in Japan |
| Bocor Chair (Zeomin) | Germany/Merz | Minimal impurities, storable at room temperature | considered the lowest | Subject to distribution conditions |
Summary｜Botox products don't necessarily have to be from Allergan
Botox that is less likely to trigger antibody formation is not only manufactured by Allergan,Core ToxやBoko ChairThere are multiple such cases.
At Bianca Clinic, we tailor our treatments to address each patient's concerns and goals. Even if it's your first time trying Botox, please feel free to consult with us.
Please also see the following▼
Is it true that Botox can cause antibodies? Causes and prevention methods you should know
