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Hello, I'm Ryutaro Natsume, an impression designer and cosmetic surgeon.

To live a vibrant healthy life, we believe that rejuvenation treatments that target not only appearance but also inner vitality are essential.

This time, we'll introduce the beauty IV drips available at BIANCA CLINIC.

We'll explain the latest regenerative medicine treatments, including the currently trending exosomes, NMN, and stem cell culture supernatant drips.

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BIANCA SHOT

Price: ¥3,630

This is BIANCA's original IV cocktail.

Skin whitening, acne/skin irritation, fatigue recovery, hangover relief, swelling

We offer solutions tailored to each individual concern.

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High-concentration glutathione　

Price: ¥17,908 (tax included)

High-concentration glutathione IV therapy is an intravenous treatment primarily composed of glutathione, which protects cells from reactive oxygen species.

Glutathione inhibits melanin production, providing whitening effects and proving effective against dark spots and melasma.

It also helps relieve fatigue and prevent aging through its antioxidant effects, and improves hangovers by supporting the liver's detoxification function.

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High-concentration vitamin C　

Price: ¥17,908 (tax included)

Vitamin C inhibits melanin synthesis, providing a whitening effect. It also helps control sebum production, making it effective for oily skin and acne.

It also promotes collagen synthesis and helps prevent wrinkles and sagging.

With its enhanced antioxidant properties, this treatment offers numerous benefits including prevention of skin aging, cancer prevention, prevention of lifestyle-related diseases, fatigue recovery, and cold prevention.

Oral intake is not sufficiently absorbed, so we recommend high-concentration vitamin C IV therapy to efficiently deliver it deep into cells.

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High-Concentration Multivitamin and Mineral Supplement

Price: ¥21,780 (tax included)

In addition to high-concentration vitamin C, it contains approximately eight active ingredients including magnesium, B vitamins, and calcium.

Compared to high-concentration vitamin C alone, it offers more effective skin beautifying effects, promotes skin regeneration and repair, and suppresses inflammation.

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BIANCA DRIP (Hydrogen Therapy)

Price: ¥23,958 (tax included)

This is BIANCA's original hydrogen therapy, which infuses hydrogen into high-concentration vitamin C IV drips and high-concentration glutathione IV drips.
Many diseases are said to be caused by "reactive oxygen species."
It has been revealed that "reactive oxygen species" are also involved in aging.
Approximately 31% of the oxygen we breathe is converted into reactive oxygen species, but stress, intense exercise, alcohol consumption, and smoking also generate reactive oxygen species within the body.

If active oxygen, which constantly occurs, is not immediately eliminated, cells and blood vessels rust, leading to disease and aging.
Hydrogen possesses powerful antioxidant properties that eliminate these reactive oxygen species.

The combination of high-concentration vitamin C, high-concentration glutathione, and hydrogen enables stronger antioxidant effects.

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NMN IV Drip / NAD+ IV Drip

Price: ¥60,500 (tax included)

For details"The Elixir of Immortality!? What are NMN and NAD+?"Please read.

The sirtuin gene, often called the "youth gene," is believed to have cancer-suppressing effects, control over stress/inflammation/immune responses, and promote antioxidant activity.
In fact, studies on mice with enhanced sirtuin gene function reported a 16.4% increase in healthy lifespan for females and a 9.1% increase for males.

NAD+, a substance found within living organisms, has the function of activating the sirtuin genes, but

NAD+ levels are said to gradually decrease starting around age 30, falling to about half of what they were in one's 20s by one's 50s.

In other words, maintaining NAD+ levels is the secret to staying young.

Additionally, NAD+ also functions as a coenzyme for ATP, the energy source (akin to gasoline for a car),

Adding NAD+Fatigue recovery and mental clarityhas the effect of.

Direct administration of NAD+ may cause side effects such as headaches, shortness of breath, and constipation, so it can also be administered in the form of its precursor, NMN.

For daily use, NMN oral supplements are recommended. If you want to feel the effects quickly, NMN IV drips are recommended. For even faster results, NAD+ is recommended.

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Exosome Infusion

Price: ¥55,000 (tax included)

Exosomes are substances secreted by stem cells.

Chronic inflammation is associated with aging.

Macrophages are involved in inflammation, and there are two types of macrophages: M1 and M2.

M1 cells play a role in inflammatory responses, attacking and eliminating bacteria and pathogens that cause inflammation. However, they can also trigger inflammatory responses to some extent in healthy tissue. This ultimately contributes to aging.

M2 macrophages possess anti-inflammatory properties that help repair post-inflammatory tissue. While extreme imbalance is problematic, it is crucial to aim for a state where M2 macrophages are predominant.

Exosomes promote M2 macrophage dominance and exert anti-inflammatory effects.

Systemic administration via intravenous drip offers a wide range of benefits, including reduced post-operative downtime, recovery from chronic fatigue, improved sleep, relief from joint pain, and enhanced concentration. Localized injection into specific skin areas can suppress inflammation, improve dark spots and wrinkles, and address thinning hair, providing a cosmetic approach.

Actually, not all exosomes are equally beneficial. Exosomes derived from senescent cells may promote M1 macrophage dominance.

Our exosomes are high-quality exosomes meticulously selected and extracted exclusively from elite stem cells—those less prone to cellular aging—among the stem cells derived from young, healthy donors.

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Purified concentrated stem cell culture supernatant infusion

¥60,258 (tax included)

Purified and Concentrated Cell Culture Supernatant Infusion is

This is an intravenous drip solution obtained by purifying and concentrating the supernatant collected during the cultivation of stem cells harvested from humans.

This supernatant solution is rich in various humoral factors, including growth factors, immune modulators, anti-inflammatory factors, and neurotrophic factors. Exosomes are also contained within it.

This regenerative medicine promotes the activity of cells weakened by aging or damage, offering potential for maintaining beauty and health.

It is purified and concentrated with careful attention to quality and safety, removing impurities such as ammonia released by cells as much as possible while retaining a high concentration of growth factors.

Key characteristics of major growth factors include...
aFGF: Stimulates fibroblasts, with expected effects on wound healing, wrinkle improvement, and skin brightening.
EGF: Promotes skin turnover and improves dark spots and dullness
IGF-1: Helps regenerate skin cells and enhances firmness and elasticity.
HGF: Promotes angiogenesis and tissue repair
TGF-β: Suppresses inflammation and improves sensitive skin conditions
PDGF: Stimulates cells responsible for tissue repair and promotes cell division
VEGF: Supports angiogenesis
KFG: Stimulates hair matrix cells to promote hair growth and regrowth
bFGF: Activates cells in blood vessels, muscles, and skin, and is also involved in nerve and bone regeneration.

It is effective in repairing various weakened cells in this way.

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So what do you recommend?

◯I got sunburned.→BIANCA DRIP (Hydrogen Therapy)

◯I want to improve my daily performance—I feel tired, my head isn't clear, etc.→Regular oral NMN + NMN IV drip or NAD IV drip when symptoms are severe

◯Post-operative downtime, muscle soreness, and other inflammation that needs to be calmed→Exosome Infusion

◯I want to prevent aging throughout my entire body.→Purified concentrated stem cell culture supernatant infusion

I use them interchangeably.

Please feel free to contact us anytime!

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Reservations can be made here.

Complete your reservation in 60 seconds ▶︎

https://reservation.medical-force.com/b/d7bb811e-ebd5-4b93-93f8-588864b24f15

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※There are various approaches to aesthetic medicine, and opinions and practices may differ among physicians. Please consider the information provided here as one reference only, and we hope you will choose medical care that suits you and meets your expectations.

We apologize if any unintended inaccuracies or misleading expressions were included. In such cases, we will make appropriate corrections or additions.

 

【Profile】

Plastic Surgeon Dr. Ryutaro Natsume

https://biancaclinic.jp/doctor/natsume/

Performed numerous facial surgeries, particularly focusing on the eye area and facial bones, in the field of plastic surgery.

Regarding treatments for the eye area, I believe that not only aesthetic appearance but also ophthalmic functionality is extremely important. To provide safer and more reliable treatments, I am currently deepening my expertise as an ophthalmologist.

We actively incorporate non-surgical procedures such as hyaluronic acid injections, in addition to treatments requiring surgical instruments.

From a multifaceted professional perspective encompassing cosmetic surgery, cosmetic dermatology, reconstructive surgery, and ophthalmology

BIANCA CLINIC, a leading Japanese clinic specializing in beauty and regenerative medicine, provides the latest aesthetic treatments.

【Career】

2020: Graduated from Tokyo Medical University Tokyo Metropolitan Saiseikai Central Hospital

2022 Jikei University Hospital Department of Plastic Surgery

2023 Department of Plastic Surgery Jikei University School of Medicine Kashiwa Hospital

2024 BIANCA CLINIC

【Professional Affiliations/Qualifications】

Japanese Society of Aesthetic Surgery (JSAS)

Full Member of the Japan Society of Plastic and Reconstructive Surgery

Full Member of the Japanese Society of Craniofacial Surgery

Full Member of the Japanese Ophthalmological Society

Full Member of the Japanese Society of Aesthetic Medicine

【SNS】

Instagram account　

 https://www.instagram.com/dr.natsume?igsh=OHBvd3VtajV1bmY1&utm_source=qr