NEAUVIA STIMULATE vs HArmonyCa カルシウムハイドロキシアパタイト製剤とは？

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2025.09.04

Supervising Physician

Ryutaro Natsume

A dual-specialty doctor with a background in plastic surgery, bridging cosmetic surgery and ophthalmology. At the university hospital, he performed numerous high-difficulty cases, primarily focusing on eye and facial bone surgeries, cultivating precise techniques grounded in anatomy. He prioritizes achieving both aesthetic beauty and functional safety, offering customized treatments around the eyes that incorporate ophthalmological expertise. He actively utilizes not only incisional surgery but also non-invasive procedures like hyaluronic acid injections. By carefully assessing each individual's condition and unique appeal, he provides bespoke treatments that guide patients toward naturally harmonious, well-defined eyes.

Hello, I'm Ryutaro Natsume, an image designer and cosmetic surgeon.

加齢とともに骨や軟部組織萎縮によるコケ、真皮のコラーゲン低下によるハリ感低下を気にされる方が多いです。

今回は両者を改善できるハイドロキシアパタイト製剤を紹介します！

ハイドロキシアパタイト(CaHA)とは人の歯や骨に含まれる成分であるリン酸カルシウムの一種です。

皮下に注入すると長期間に渡ってコラーゲン生成効果があり真皮のボリュームを増やし、ハリ感を出します。

ヒアルロン酸と組み合わせたデュアル効果ハイブリッド注射製剤が登場しました！

・ヒアルロン酸による即時ボリュームアップとリフティング効果
・カルシウムハイドロキシアパタイトによる緩やかで長期的なコラーゲン生成促進効果

can be expected.

従来のヒアルロン酸製剤では出せなかった効果が得られます。

◯NEAUVIA STIMULATE

CaHA濃度は低め(1%)

NEAUVIAシリーズ全てにおいてアレルギー報告０件(ヒアルロン酸アレルギーの原因物質であるBDDEを使用していないため)

あくまでボリュームをしっかり出しつつ、コラーゲン生成もある程度期待したい時に使用します。

◯ハーモニカ(HArmonyCa)アラガン社

CaHA濃度が高い(55%)

コラーゲンが減ってきた30歳代後半で、比較的皮膚が薄い方　におすすめ

ある程度のボリュームを改善させつつ、しっかりコラーゲン生成して肌のハリを出すのに効果的です

アンチエイジング目的での使用が良いでしょう

使い分けのまとめ

◯NEAUVIA STIMULATE→

20-30歳代

しっかりボリュームを出して輪郭形成したい、ハリ感も少し出したい

◯ハーモニカ(HArmonyCa)アラガン社

30歳代後半で、比較的皮膚が薄い方

肌育効果メイン、ボリュームはやや控えめでナチュラルな仕上がり

ハイドロキシアパタイト(CaHA)製剤を取り扱っているクリニックは国内でもまだ少ないです。

治療経験の多い当院に是非お気軽にご相談ください！

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※There are various approaches to aesthetic medicine, and opinions and practices may differ among physicians. Please consider the information provided here as one reference only, and we hope you will choose medical care that suits you and meets your expectations.

We apologize if any unintended inaccuracies or misleading expressions were included. In such cases, we will make appropriate corrections or additions.

【Profile】

Plastic Surgeon Dr. Ryutaro Natsume

https://biancaclinic.jp/doctor/natsume/

Performed numerous facial surgeries, particularly focusing on the eye area and facial bones, in the field of plastic surgery.

Regarding treatments for the eye area, I believe that not only aesthetic appearance but also ophthalmic functionality is extremely important. To provide safer and more reliable treatments, I am currently deepening my expertise as an ophthalmologist.

We actively incorporate non-surgical procedures such as hyaluronic acid injections, in addition to treatments requiring surgical instruments.

From a multifaceted professional perspective encompassing cosmetic surgery, cosmetic dermatology, reconstructive surgery, and ophthalmology

BIANCA CLINIC, a leading Japanese clinic specializing in beauty and regenerative medicine, provides the latest aesthetic treatments.

【Career】

2020: Graduated from Tokyo Medical University Tokyo Metropolitan Saiseikai Central Hospital

2022 Jikei University Hospital Department of Plastic Surgery

2023 Department of Plastic Surgery Jikei University School of Medicine Kashiwa Hospital

2024 BIANCA CLINIC

【Professional Affiliations/Qualifications】

Japanese Society of Aesthetic Surgery (JSAS)

Full Member of the Japan Society of Plastic and Reconstructive Surgery

Full Member of the Japanese Society of Craniofacial Surgery