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2024.09.21
A Doctor Explains Azelaic Acid's Effects and Precautions! What Ingredients Should Not Be Used Together?
With deep medical insight cultivated as an internal medicine specialist, I bridge aesthetic surgery, dermatology, and internal medicine. Having spent my childhood in China, I communicate fluently in Japanese, Chinese, English, and Korean. Possessing an international perspective—evidenced by invitations to present at overseas conferences—I actively promote techniques as a Key Opinion Leader (KOL) for GOURI and REJURAN®. My specialty procedures include double eyelid surgery, skin-nurturing boosters, and body hyaluronic acid treatments. My approach leverages the holistic understanding of the body cultivated through internal medicine to guide patients toward natural, healthy beauty.
Hello, everyone.
Dr. Hime of BIANCA CLINIC, also known as Senki Akashi.
Lately, you see "cosmetics containing azelaic acid" all over social media, right?
But in reality, many people still don't know what ingredients it contains or who it's suitable for, do they?
Today, we'll discuss how to effectively use azelaic acid—a skin-conditioning ingredient currently in the spotlight—along with ingredients that are safe to use alongside it and those you should avoid.
What is azelaic acid?

Azelaic acid is a naturally occurring acid found in grains such as rye and wheat, and it is gaining attention as an ingredient that promotes healthy skin.
Azelic acid has long been used overseas as a skincare and skin care ingredient, and in Japan, skincare items containing azelaic acid are also gaining attention.
What are the main functions of azelaic acid and what skin types is it suitable for?
The main functions of azelaic acid are as follows.
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Keep your skin healthy
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Balance dryness and shine
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Protects moisture while preventing skin roughness
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Smooths the skin's surface
Incorporating it into your daily skincare routine can help balance your skin and guide it toward a soft, healthy complexion.
Azelaic acid is,For those prone to sebum imbalance or whose skin becomes unstable during seasonal transitionsIt is a skin-conditioning ingredient that is easy to incorporate.
It should be easy to use even for those with “multiple skin concerns” such as rough texture, dryness, and redness.
Ingredients to avoid using with azelaic acid
Azelaic acid may cause irritation depending on the ingredients used in combination with it.
especially the followingKeratin care ingredientsIt is advisable to avoid using them simultaneously.
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Retinol (Vitamin A derivative): As it promotes skin turnover, dryness or redness may occur when used in combination with other products.
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AHA (glycolic acid, etc.) and BHA (salicylic acid, etc.): These ingredients remove dead skin cells, which can make your skin more sensitive.
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High-concentration Vitamin C (L-ascorbic acid): Since both are acidic, you may experience irritation or dryness. Use them at separate times.
If you want to use these ingredients too, on days you use azelaic acid,Take a break from exfoliationorUse one in the morning and another at nightIt's reassuring.
Ingredients that are compatible with azelaic acid and can be used together
In fact, azelaic acid can be used more gently when combined with other skin-conditioning and moisturizing ingredients.
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Hyaluronic Acid: Provides moisture and prevents dryness
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Ceramide: Supports the skin's barrier function and soothes sensitive skin.
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Niacinamide: Supports a translucent complexion while refining skin texture
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Panthenol (Provitamin B5): Prevents skin irritation and maintains healthy skin.
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Dipotassium Glycyrrhizate: A skin-conditioning ingredient that promotes healthy skin
Using these ingredients together gently enhances the effects of azelaic acid while minimizing irritation.
Precautions When Using Azelaic Acid
Azelaic acid is gentle on the skin, but you may experience a slight tingling sensation when you first start using it.
In that case, adjust by reducing usage to 2-3 times per week and ensuring thorough moisturization.
Also,Skin immediately after peeling or sunburnPlease avoid using it.
Summary: The secret to successful azelaic acid care is to keep it gentle and consistent.
Azelaic acid is a skin-conditioning ingredient chosen by those who wish to maintain healthy skin while refining its texture.
However, using it simultaneously with other keratin care ingredients may increase the risk of irritation, so firstSimple care focused on moisturizingStarting with this will give you peace of mind.
Take your time and continue at your own pace, without rushing.
▼If you're concerned about skin redness, please also see this section.
https://biancaclinic.jp/blog/44595/
▼BIANCA CLOSET carries this item.
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