Rituo Re2O (Bunaju)
BNAJU
Directly supplements deficient collagen and leads to healthy skin
Next generation skin booster
- Directly works on the “skin foundation” rather than on the surface of the skin to lead to younger looking skin
- Human-derived collagen formulation with an emphasis on ease of absorption into the skin
- Injection therapy that is easy to continue and burdensome
Engaged in both aspects of cosmetic dermatology and cosmetic surgery, he is an all-rounder doctor who pursues natural and elegant beauty with "the best interest of the patient" as his first priority. He is also a board-certified cosmetic surgeon by the Japanese Society of Aesthetic Plastic Surgery (JSAS). He specializes in hyaluronic acid injections, thread lifts, and facial surgery, and is a competent KOL (Key Opinion Leader) for ARTEMISLIFT and Hydro Rejuran. He is always sensitive to the latest trends and is always exploring knowledge and techniques.
Case Presentation
CASES
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Left: Before surgery Right: One month after surgery
*This graph shows the ranking (percentile) of skin condition compared to the same age group. Yellow is the evaluation before the treatment and purple is the evaluation at one month after the treatment. After the treatment, an increase in score is observed, and it can be confirmed that the wrinkle condition has improved to a more favorable level compared to the same age group. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
- Rituo Re2O (Bunaju): 110,000 yen per session; topical anesthesia fee: 3,630 yen
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Left: Before surgery; Right: 1.5 months after surgery
*This graph shows the skin condition ranking (percentile) compared to peers of the same age. Yellow represents the pre-treatment assessment, and purple represents the assessment 1.5 months after treatment. An increase in the score is evident after treatment, confirming that the condition of wrinkles has improved to a better level compared to peers of the same age. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
-
1 session: 115,500 yen
Topical Anesthetic Fee: 3,630 yen
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Upper: before treatment Lower: 8 weeks after treatment
This case is a reference case provided by the supplier of the formulation. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
- Rituo Re2O (Bunaju): 110,000 yen, surface anesthesia fee: 3,630 yen
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Upper: before treatment Lower: 8 weeks after treatment
This case is a reference case provided by the supplier of the formulation. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
- Rituo Re2O (Bunaju): 110,000 yen, surface anesthesia fee: 3,630 yen
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Upper: before treatment Lower: 3 days after treatment
This case is a reference case provided by the supplier of the formulation. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
- Rituo Re2O (Bunaju): 110,000 yen, surface anesthesia fee: 3,630 yen
Re2O Re2O (Bunaju)
- Treatment Period and Number of Sessions
-
Upper: before treatment Lower: 8 weeks after treatment
This case is a reference case provided by the supplier of the formulation. - Side Effects and Risks
- Swelling, redness, swelling, microscopic nodules, etc.
- Cost
- Rituo Re2O (Bunaju): 110,000 yen, surface anesthesia fee: 3,630 yen
Extensive experience in injection therapy makes a difference in the realization of effects.
Rituo (Bunaju) is a treatment injected manually by a physician while assessing the skin condition of each individual. Since adjustments to the amount, depth, and location of the injection directly affect the finished product, the realization of effects and satisfaction are largely dependent on the skill of the physician.
At our clinic, the treatment is performed by physicians with extensive experience in injection therapy. If desired, a high-performance skin diagnostic machine: VISIA can be used during the counseling. After objectively analyzing the skin condition before and after the treatment, we will design the optimal treatment.
Downtime
DOWNTIME
Recommended for people like this
RECOMMENDED.Features
CHARACTERISTICSWhat is Lituo (Bunaju)?
Rituo (Bunaju) is a next-generation collagen formulation whose main ingredient is human acellular dermal matrix (hADM), which is carefully extracted and purified from human tissue. It directly addresses skin problems such as dark circles under the eyes and wrinkles that appear with age, bringing out natural and youthful beauty from within.
Of particular note is that it contains a balance of type I collagen, which supports the skin's firmness and structure, and type III collagen, which is essential for youthful skin. type I collagen is the main structural component of the dermis and supports the skin from the inside, while type III collagen balances around it and helps maintain a smooth skin structure. Type III collagen is responsible for maintaining the smooth structure of the skin while balancing the surrounding collagen.
The composition of the formulation containing two types of collagen efficiently replenishes collagen lost with aging and supports the skin's natural healing ability and stability.
Skin booster that directly supplements ECM components that decrease with age
The firmness and elasticity of our skin is fundamentally supported by a mesh-like foundation called the ECM (extracellular matrix) that extends around the cells. This ECM not only physically supports skin cells and maintains tissue structure, but also functions as an important foundation for cells to exchange information with each other, maintaining the youthfulness of the entire skin. However, as we age, this ECM changes, which can lead to the appearance of aging signs such as wrinkles and sagging.
Lituo (Bunaju) directly replenishes the skin with the components of the ECM, which is the very foundation of the skin.
By replenishing the constituent components of ECM, it is characterized by its ability to improve the skin from the foundation up, naturally enhancing skin firmness, elasticity, and moisture. By working on the skin's structure rather than providing temporary care, we aim to achieve lasting, natural beauty.
The difference from conventional skin boosters is
Most conventional skin boosters take the approach of stimulating the skin with drugs to encourage its own cells to "make" collagen. While this method is a wonderful treatment that draws out the skin's natural healing power, it also has the problem of not being as effective as expected when the cells themselves are less responsive due to aging or other factors.
Rituo (Bunaju) is a collagen skin booster that fundamentally changes this concept. Instead of "stimulating" collagen production, it directly "replenishes" the skin with human-derived ECM components such as collagen and elastin, which are the foundation of the skin. This allows the skin's structure to be regenerated from the foundation up, without relying on the production capacity of its own cells. Even those who have had difficulty in feeling the effects of other treatments can expect to experience improved elasticity, firmness, and moisture.
Benefits
MERITSupplements the skin's foundation ingredients and approaches various skin problems
By supplementing the ECM components that form the foundation of the skin, it fundamentally addresses not only wrinkles but also other complex skin problems such as lack of firmness, texture, and moisture.
Human-derived collagen is easily absorbed into the skin
Since human-derived collagen is used, it is said to be less likely to cause foreign body reactions, and natural-looking results can be expected while taking into consideration the risk of foreign body reactions.
The treatment time is short and the skin is taken into consideration.
The procedure is easy for busy people to undergo because it is an injection-only procedure with short treatment time and minimal downtime.
Recommended Features
KEY FEATURESDifference between hyaluronic acid injections and retuo (Bunaju)
Collagen preparations, as well as hyaluronic acid injections and Lituo (Bunaju), are both procedures in which the preparation is injected directly into the skin, but there are differences in their purposes and approaches. Hyaluronic acid injections are primarily intended to supplement volume in specific areas or to physically fill in deep wrinkle grooves and hollows. The injected hyaluronic acid preparation is absorbed by the body over time and is gradually absorbed.
Rituo (Bunaju), on the other hand, is an injection treatment using a collagen preparation that works on the skin structure itself to improve the skin's foundation. The injected collagen is not only absorbed, but is also involved in the skin's internal environment. It functions as a scaffold for your own cells to work, and you may see changes in the condition of your skin over time. In this way, the unique feature of Lituo (Bunaju) is that it aims to rebuild the skin from its foundation, rather than simply replenish volume.
Blends well with the skin for a natural finish
Since Rituo (Bunaju) directly replenishes the skin's own collagen and other ECM structural components, it blends extremely well with the skin, giving it a natural look as if it had always been that way. The formulation is soft, so there is almost no risk of unevenness or transparency even when injected into thin areas of the skin. Therefore, it is possible to smooth out delicate areas with thin skin, such as fine wrinkles around the eyes, which are difficult to treat with hyaluronic acid or Botox injections. By adjusting the skin's structure, it leads to a natural and youthful impression.
Micro cannula injection to minimize pain and internal bleeding
Many people are concerned about pain when they hear the word "injection". In consideration of this concern, we use a special needle called a "micro cannula" for the procedure. Unlike ordinary injection needles, the micro cannula is extremely thin and has a rounded tip. This special shape prevents damage to blood vessels and tissues under the skin, reducing the risk of downtime, such as internal bleeding and swelling after the procedure, as well as pain during the procedure. The delicate eye area can be treated with greater peace of mind.
Treatment area
TREATMENT AREAFine wrinkles around the eyes, forehead, between the eyebrows, nasolabial folds, etc.
Treatment Process
TREATMENT FLOWPhysician's examination and counseling
After hearing about your concerns and wishes and examining your skin condition, we will determine the indications for Rituo (Bunaju). We will then provide you with a detailed explanation of the procedure, treatment flow, and fees.
Makeup removal at the injection site
You will be required to remove makeup and wash your face before the procedure. Cleansing agents and face washes are available at our clinic.
treatment
The doctor will inject the Lituo (Bunaju) into the desired treatment area using a micro cannula. The treatment time varies from person to person depending on the area to be injected and the extent of the treatment, but it is estimated to take about 10 minutes. After confirming that the bleeding has stopped in the affected area, the procedure is complete.
Aftercare
After confirming the results with the doctor, you may apply makeup and leave if there are no issues. Following the procedure, the injection site may temporarily appear red, but this will fade over time.
Schedule of Charges
PRICE LIST| Product Name | 1 time | 3 times |
|---|---|---|
| Re2O Re2O (Bunaju) | 115,500 yen | 311,900 yen |
Surface anesthesia fee: 3,630 yen
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
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FOR YOUR CONCERN
Retuo Re2O (Bunaju) Frequently Asked Questions
Q&AHow long do the effects of Lituo (Bunaju) last?
Although it varies from person to person, the duration of the effect is approximately six months to one year. Regular maintenance is expected to maintain better skin condition.
What is the ideal frequency of receiving a rituo (bunaju)?
Since the purpose of the Rituo (Bunaju) treatment is to focus on the foundation of the skin, we recommend that the treatment be performed first once a month for a total of three sessions. After that, maintenance is generally performed once every six months in most cases, depending on the condition of the skin.
What do I need to know before receiving a rituo (bunaju)?
Since Rituo (Bunaju) uses a preparation derived from human skin tissue, you will not be able to donate blood after the procedure. Please understand this in advance before considering the procedure.
What is the recommended treatment to combine with Rituo (Bunaju)?
After confirming the skin condition and concerns during the consultation, we will propose the best combination of treatments, such as thread lift for those who are concerned about sagging skin, and PicoFractional for those who want to improve the overall skin texture.
How safe is Lituo (Bunaju)?
Lituo (Bunaju) is a collagen preparation that is mainly composed of human cell-free dermal matrix (hADM) from which cellular components have been removed from human-derived tissues. Because it does not use animal-derived components, it is generally considered a material with a low risk of immune or allergic reactions. However, not all patients are free from side effects, so a physician will examine the patient prior to the procedure to confirm the patient's physical constitution and medical history before determining the indication for the procedure.
When can I start wearing makeup after the Rituo (Bunaju) treatment?
Makeup can be applied on the same day as long as the treatment area is avoided.
When is it OK to shower or bathe after a Rituo (Bunaju) treatment?
There are no restrictions on showering on the day of treatment. Bathing is allowed from the following day.
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[Description of treatment] Lituo (Bunaju)
Approximate duration and number of treatments: 3 sessions every 4 weeks *Depends on the condition.
Risks and side effects] Swelling, redness, swelling, microscopic nodules, etc.
【Important Notes Regarding Unapproved Medicines】
・This treatment may involve the use of unapproved pharmaceuticals that have not received regulatory approval in Japan.
・Medicines used in treatments are imported through personal import procedures under the supervision of a physician. For details, please refer to the Ministry of Health, Labour and Welfare's "Information on Medicines Requiring Caution for Personal Import."
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there may be no other domestically approved pharmaceuticals containing the same ingredients.
・Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, you may not be eligible for the national pharmaceutical adverse reaction victim relief system.
Patients who have undergone this procedure will not be able to donate blood for a certain period of time.
