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2026.07.22
What Is BNAJU Eye? A Cosmetic Surgeon Provides a Comprehensive Explanation of Its Effects, Ingredients, Indications, and How It Differs from Rejuran Eye
Engaged in both aspects of cosmetic dermatology and cosmetic surgery, he is an all-rounder doctor who pursues natural and elegant beauty with "the best interest of the patient" as his first priority. He is also a board-certified cosmetic surgeon by the Japanese Society of Aesthetic Plastic Surgery (JSAS). He specializes in hyaluronic acid injections, thread lifts, and facial surgery, and is a competent KOL (Key Opinion Leader) for ARTEMISLIFT and Hydro Rejuran. He is always sensitive to the latest trends and is always exploring knowledge and techniques.
Doctors' Point
If you want to naturally improve “fine lines under the eyes,” “dark circles,” and “loss of firmness”—BNAJU Eye is the next-generation skin booster designed to meet those needs.
In the field of cosmetic surgery as well, the concept of replenishing the ECM (extracellular matrix) to rebuild the skin’s “foundation” is gaining attention. Unlike hyaluronic acid, which plumps the skin, this approach improves the tissue environment to enhance skin texture and firmness.
In this article, we’ll provide an easy-to-understand explanation from a cosmetic surgeon’s perspective of Bunaju Eye’s ingredients, mechanism of action, expected effects, indications, and downtime, as well as how it differs from Rejuran Eye and hyaluronic acid. Please note that this article is based on general knowledge and does not contain any information derived from data specific to any particular clinic.
What is BNAJU Eye?
Bunajuai is a skin booster specifically designed for the eye area that uses a micro-sized ECM formulation derived from human-derived decellularized dermis (hADM). It retains ECM components such as collagen, elastin, laminin, and fibronectin while removing cellular components from human dermis.
The goal is to replenish the skin’s “foundation” while minimizing the risk of an immune response. The particles are optimized for the eye area and are designed to spread evenly even in the superficial layers.
What is the ECM (Extracellular Matrix)?
The ECM serves as a scaffold for cellular function; to use a house as an analogy, it is equivalent to the “foundation.” When the ECM is damaged by aging or UV rays, collagen and elastin levels decrease, leading to skin thinning, loss of firmness, and the development of fine lines and dark circles.
Bunajuai aims to create this environment and help the skin reach a state where it can function at its best.
Expected Effects
- Restoring Firmness and Elasticity to the Eye Area
- Improving Crepe-Like Wrinkles and Fine Lines
- Improved Skin Thickness and Texture
- Reducing dryness, improving skin texture
- Improvement of Mild Dark Circles (Caused by Visible Blood Vessels or Thinning Skin)
On the other hand, structural issues such as protruding orbital fat or deep hollows may not improve sufficiently with this procedure alone. In such cases, other treatment options are considered.
Mechanism of Action: “Nurturing,” Not Just Filling
- Activation of Fibroblasts
- Promotion of Collagen and Elastin Production
- Promoting Hyaluronic Acid Production and Improving the Skin's Moisture-Retaining Environment
- Establishing a Microenvironment Suitable for Tissue Repair
Bunajuai is not primarily intended to add volume; rather, it is an approach that focuses on preparing the skin’s foundation to enhance its texture and thickness.
Indications and Ideal Candidates, According to a Cosmetic Surgeon
- Fine lines that appear when you smile, and fine lines caused by dryness
- I'm concerned about my skin being thin and lacking firmness
- Types of dark circles characterized by thinning of the skin or slight vascular transparency
- People who want a natural rejuvenation without making their face look puffy
- People who are hesitant about hyaluronic acid, or those who want to take preventive measures for the future
Protruding fat, deep indentations, and skeletal shadows require a different approach. To help you choose a treatment, focusing on the changes in texture in the “Before & After” images will give you a better understanding.
Differences from Rejuran Eye
Rejuran Eye is a formulation containing PN (polynucleotide) derived from salmon that delivers “repair signals.” In contrast, Bunaju Eye contains human-derived ECM that supplements the “foundation for cellular activity.” While both are based on the concept of skin nurturing, their approaches complement each other in distinct ways.
Differences from Hyaluronic Acid
While hyaluronic acid is excellent for adding volume, there are concerns about swelling and the Tyndall effect when used around the eyes. Bunajuai prioritizes texture and has the advantage of smoothing the skin’s surface without causing swelling.
Cosmetic Surgery Treatment Protocols and Downtime
Generally, one course consists of three sessions spaced 3 to 4 weeks apart, followed by maintenance treatments every 3 to 6 months. Downtime primarily involves redness, swelling, pinpoint bleeding, mild bruising, and tenderness, most of which subside within a few days.
On the day of your procedure, please refrain from strenuous exercise, alcohol consumption, and using saunas. At our cosmetic surgery clinic, we fine-tune the injection depth and volume based on your skin condition to achieve a natural-looking result.
Assessing the Effect on Bears
There are various causes, including pigmentation, vascular issues, thinning of the skin, shadows, and protruding fat. Bunajuai is suitable for cases of thinning skin or mild vascular transparency. For shadows or protruding fat, it is helpful to combine this treatment with other therapies.
Strategies for Combining with Other Treatments
Depending on your goals, combining treatments such as Botox, laser and radiofrequency therapies, hyaluronic acid, fat grafting, and the Ura-Hamura method can lead to comprehensive improvements. The key is a multifaceted strategy tailored to the root cause of your concerns.
Safety and Risk Management in Cosmetic Surgery
Common risks include bruising, infection, swelling, inflammation, asymmetry, and rare allergic reactions. It is important to perform the procedure based on anatomical knowledge, maintain sterile technique, and provide postoperative follow-up.
Since we are not currently referring to any specific clinic’s proprietary data, please check with the cosmetic surgery clinic where you plan to receive treatment for details.
Summary
BNAJU Eye is a new skin booster designed to improve firmness, elasticity, fine lines, and skin texture around the eyes by replenishing human-derived ECM (extracellular matrix).
Its mechanism of action differs from that of Rejuran Eye or hyaluronic acid, making it suitable for those who prioritize a natural-looking improvement in skin texture. However, it cannot address all types of dark circles and wrinkles on its own; depending on the cause, it may be better to combine it with other treatments, such as hyaluronic acid or the Ura-Hamura method.
Since it is important to accurately identify the cause of eye area concerns, we recommend that you consult with an experienced cosmetic surgeon and choose a treatment plan that is right for you.
