Methylene Blue Infusion (Brain Function Stimulation)
METHYLENE BLUE IV INFUSIONS
Supports brain health at the cellular level
Intravenous Therapy Focused on Energy Metabolism
- Supports the brain's energy metabolism and helps improve concentration and memory
- Protects nerves and regulates the function of neurotransmitters
- Reduces oxidative stress and supports brain and overall health
To maximize your beauty, care for both the inside and outside is essential. We aim to bring advanced anti-aging treatments, such as peptide therapy common overseas, to our Japanese patients. While aesthetic medical approaches may offer more gradual results, they are crucial for building the foundation that supports beauty and youth. We combine nutritional therapy and lifestyle improvements with hormone replacement, peptide therapy, and regenerative medicine to propose personalized treatment plans. We provide long-term support for health and beauty from within.
With reliable knowledge based on aesthetic medicine,
Supports not only skin and body health, but also brain health
At Bianca Clinic, guided by the belief that “physical and mental beauty and youthfulness are supported by a healthy internal environment,” we also focus on aesthetic internal medicine rooted in longevity medicine. Our aesthetic medicine menu is supervised by physicians who are experts in the field. Even with regard to methylene blue IV therapy, we provide an approach grounded in medical expertise.
During a methylene blue IV treatment, a physician with specialized expertise in aesthetic medicine will administer the appropriate dose based on your condition and preferences. Why not try this convenient inner care treatment in a sophisticated, private setting—and focus not only on the health of your skin and body, but also on the health of your brain, which works tirelessly every day?
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED.Features
CHARACTERISTICSWhat Is a Methylene Blue Infusion?
Among the body’s organs, the brain consumes a relatively large amount of energy and oxygen, and brain neurons are prone to oxidation. Therefore, regulating energy metabolism and countering oxidative stress are essential for maintaining brain health.
At our clinic, we use a methylene blue IV drip—formulated with medical-grade methylene blue—to promote brain health and support concentration and cognitive function.
What Is Methylene Blue?
In recent years,
・Supports energy metabolism by targeting mitochondrial* function
・Has antioxidant properties and protects cells from oxidative stress
・Protects nerve cells and supports the function of neurotransmitters
This aspect is also drawing attention.
Methylene blue is gaining attention in Europe and the United States not only for intravenous infusions but also as an oral medication and dietary supplement.
*Mitochondria… Small organelles found inside cells that produce the energy the body needs
A treatment that focuses on the brain while also providing holistic care for the entire body
In other countries, methylene blue IV therapy is sometimes used as one option to address issues such as brain fog*, fatigue, and decreased physical performance. Globally, it is considered one of the IV therapies expected to provide systemic anti-aging care at the cellular level.
*Brain fog… a condition in which you feel as if your brain is shrouded in fog, leading to a decline in concentration and cognitive function
Benefits
MERITMethylene blue can be efficiently delivered into the body via an IV drip.
Because it is administered directly into a blood vessel, methylene blue can be delivered to the body quickly and efficiently.
You can consult a doctor about brain health as you age
You can consult with a physician who specializes in aesthetic medicine to discuss brain aging care that takes into account not only your current condition but also your future.
Relatively short downtime and treatment time
The IV treatment takes about 30 minutes, and since there are no particular restrictions on your daily activities afterward, you can easily fit it into your schedule—even while running errands or shopping.
Recommended Features
KEY FEATURESRigorous Quality Control and Dosage Adjustment
Our clinic uses only medical-grade formulations for methylene blue IV infusions. We dissolve a formulation containing 10 mg of methylene blue and administer it over approximately 30 minutes.
In addition, to prevent the rare risks associated with methylene blue IV therapy, we always perform a preliminary G6PD blood test before the first treatment. Since we use a test kit, the results are available immediately. We have established a comprehensive testing system to ensure safety while providing methylene blue IV therapy.
Inner Care: A Holistic Approach to Beauty and Health
Bianca Clinic places equal emphasis on inner care as well as external treatments. This is because we believe that outer beauty and inner well-being are two sides of the same coin, and that maintaining a balanced approach to both leads to optimal physical and mental health.
In addition to concerns about brain health—such as work or study performance and brain fog—please feel free to consult with us about any other physical or mental health issues that are on your mind. Through treatment plans tailored to your lifestyle, we’ll help you restore balance from the inside out and bring out your natural beauty and well-being.
Offering a wide range of cosmetic medicine treatments to support your health
Our clinic offers a wide range of aesthetic medicine treatments to support your health, including intravenous methylene blue therapy. Our physicians, who possess specialized expertise in aesthetic medicine, can propose customized treatment plans tailored to each patient based on their consultation and test results.
In addition to methylene blue IV therapy, our doctors will provide guidance on high-dose vitamin C IV therapy, peptide therapy, and orthomolecular nutrition therapy, depending on each patient’s condition and goals. Whether you’d like to “hear a general overview first” or “just learn about the cost and treatment schedule,” we’ll tailor our explanation to your needs, so please feel free to ask.
Treatment area
TREATMENT AREA
A solution containing methylene blue will be administered via IV into either the left or right arm.
IV drip duration: About 30 minutes
Treatment Process
TREATMENT FLOWPhysician's examination and counseling
The doctor will take the time to listen carefully to your current health condition, any medications or supplements you are taking, and any concerns you may have.
G6PD Pre-Test (First Visit Only)
Because individuals with G6PD deficiency are at risk for hemolytic anemia*, a pre-treatment G6PD screening test via blood draw is mandatory before administering a methylene blue infusion. The test uses a kit and provides results quickly.
*Hemolytic anemia… a condition in which red blood cells are damaged, leading to anemia
Treatment (IV drip)
You will receive an IV drip for about 30 minutes while seated in a special reclining chair.
After the treatment
Once the IV drip is finished, please wait until you are sure there are no changes in your condition, and then you may go home. Your urine, stool, and sweat may temporarily turn blue or green. If you have any other concerns, please consult your doctor.
Schedule of Charges
PRICE LIST| Treatment Details | 1 time |
|---|---|
| Methylene Blue Infusion Brain Function Activation | 34,700 yen |
| G6PD Pre-Screening Fee *First treatment only | ¥11,000 |

Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
Frequently Asked Questions About Methylene Blue Infusions (for Brain Function Activation)
Q&ADoes a methylene blue IV drip hurt?
You may feel a slight prick when the IV needle is inserted. You may also experience some pain in the vein, but this can be alleviated by adjusting the IV drip rate, so please let us know right away.
Can you really feel a difference after just one IV treatment?
The extent to which patients notice changes varies from person to person. At our clinic, some patients receive continuous methylene blue IV infusions about once every two weeks to once a month.
Is it true that the color of your urine or stool changes after a methylene blue IV infusion?
Yes, that's true. After receiving an IV, the color of your urine, sweat, and stool may temporarily change to blue or green. If you have any concerns, please consult your doctor.
Are there people who can't receive a methylene blue IV drip?
This treatment is not available to individuals with G6PD deficiency, those currently taking antidepressants (such as SSRIs or SNRIs), pregnant or breastfeeding women, or those with severe kidney dysfunction.
Can I get this as part of a package with other beauty IV treatments?
Yes, you can receive this treatment in combination with other beauty IV drips. However, depending on your physical condition or any medications you are currently taking, there may be some beauty IV drips that you cannot receive, so please consult your doctor for details.
What is the difference between a methylene blue IV drip and supplements?
An IV drip delivers substances directly into the bloodstream, while supplements are taken orally. Because they are metabolized differently in the body, it is important to choose the appropriate method based on your goals and condition.
Why is a blood test required before an IV?
This is to determine whether the patient has G6PD deficiency, which carries a risk of hemolytic anemia, and to decide whether the procedure can be performed.
Can I get it done on the same day without an appointment?
Depending on the day’s availability, we may be able to accommodate you, but please note that we may not be able to do so depending on our stock of products. To ensure we have available slots for consultations and treatments, we ask that you make a reservation in advance online or by phone.
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BLOG[Treatment Details] Methylene Blue IV Drip
[Recommended Treatment Frequency and Duration] About once every 2 weeks to 1 month *May vary depending on your condition.
【Side Effects and Risks】
1. Significant Risks
・Concomitant use with antidepressants (SSRIs, SNRIs, etc.)
・G6PD deficiency (a G6PD test is required prior to treatment)
・Pregnant women and nursing mothers
・Severe renal impairment
2. Common Side Effects:
・Discoloration of urine, stool, and sweat: They turn blue to green for a few days.
・Gastrointestinal symptoms: nausea, abdominal pain, etc.
・Temporary symptoms: headaches, dizziness, high blood pressure, etc.
3. Precautions During Treatment: False-low SpO2 readings, extravascular leakage
4. Other Risks and Side Effects: Pain from the IV needle insertion, bruising, etc.
【Important Notes Regarding Unapproved Medicines】
・This treatment may involve the use of unapproved pharmaceuticals that have not received regulatory approval in Japan.
・Medicines used in treatments are imported through personal import procedures under the supervision of a physician. For details, please refer to the Ministry of Health, Labour and Welfare's "Information on Medicines Requiring Caution for Personal Import."
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there may be no other domestically approved pharmaceuticals containing the same ingredients.
・Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, you may not be eligible for the national pharmaceutical adverse reaction victim relief system.