column (e.g. in newspaper)
2026.07.15
A Comprehensive Guide to the Drawbacks of Re2O | A Plastic Surgeon Explains Precautions, Side Effects, and Who Should Avoid It
Engaged in both aspects of cosmetic dermatology and cosmetic surgery, he is an all-rounder doctor who pursues natural and elegant beauty with "the best interest of the patient" as his first priority. He is also a board-certified cosmetic surgeon by the Japanese Society of Aesthetic Plastic Surgery (JSAS). He specializes in hyaluronic acid injections, thread lifts, and facial surgery, and is a competent KOL (Key Opinion Leader) for ARTEMISLIFT and Hydro Rejuran. He is always sensitive to the latest trends and is always exploring knowledge and techniques.

Doctors' Point
Rituo is not a treatment aimed at “dramatic changes”; rather, it is a “skin-nurturing treatment” that gradually improves skin firmness, radiance, and texture. Therefore, for those expecting significant results after just one session, or those looking to improve deep wrinkles, sagging, or loss of volume, combining this treatment with others may lead to greater satisfaction.
In addition, as is true of any injectable treatment, there is always a possibility of downtime and side effects, such as redness, swelling, and bruising. When undergoing treatment, it is important to fully understand not only the benefits but also the potential drawbacks, and to choose a treatment that suits your skin condition and goals.
Re2O is gaining attention as a next-generation skin booster originating in South Korea. It is gaining popularity among those who prefer natural beauty products, as it aims to improve skin firmness and radiance, reduce fine lines caused by dryness, and enhance overall skin quality. On the other hand, concerns such as “Are there any drawbacks to Re2O?”, “Is it really safe?”, and “Do people regret getting the treatment?” are not uncommon in clinical settings. During consultations at cosmetic surgery clinics, making an informed decision—based on a clear understanding not only of the benefits but also of the drawbacks, limitations, and potential side effects—is directly linked to patient satisfaction.
In this article, based on general insights from the clinical practice of cosmetic surgery, we’ll outline the disadvantages, downtime, and risks of Re2O, as well as who it’s suitable for and who it isn’t, how it differs from other procedures, and key points to consider when choosing a cosmetic surgery clinic. We’ll also explain how to interpret “Before & After” photos and manage your expectations, providing clear guidance so that even first-time patients can make an informed decision.
What Is Re2O? Understanding Its Characteristics and Basics
Rituo is a skin booster formulation designed to optimize the skin’s moisture retention and texture. Unlike treatments that add volume, such as hyaluronic acid fillers, it focuses on improving the skin’s overall condition. The goal is not to “change facial features,” but to “enhance the natural texture of the skin itself.”
For this reason, the focus is on natural changes that make others think, “She seems to have gotten prettier somehow.” While this characteristic is an asset, it can be perceived as a drawback if expectations are set incorrectly.
A Cosmetic Surgeon Explains: A Comprehensive Overview of the Drawbacks of Rituo
Disadvantage 1: It’s hard to see dramatic results right away
The most notable drawback of Lituo is that it’s difficult to achieve dramatic, photo-ready results in a single session. Since skin is a tissue that undergoes constant renewal and repair, changes appear gradually.
Rather than focusing on the goal of “getting quick results before an event,” it’s better to adopt an approach that aims to improve your skin’s condition over a period of several weeks to several months. At a cosmetic surgery clinic, it’s important to clarify this timeframe during the initial consultation and agree on specific goals together.
Disadvantage 2: It often assumes multiple iterations and maintenance
Skin improvement is a cumulative process. The typical plan involves a few initial sessions followed by maintenance treatments.
Since this often doesn’t align with the goal of “completing the process in a single session,” scheduling with an eye toward long-term continuity is key. In cosmetic surgery, treatment intervals and the frequency of follow-up visits are optimized to fit your daily routine.
Disadvantage 3: There is some downtime (it’s not zero)
Since this is an injection treatment, some downtime is unavoidable. Redness, swelling, mild bruising, swelling at the injection site, and tenderness may occur temporarily. Most of these symptoms subside within a few hours to a few days, but bruising may persist for 1 to 2 weeks.
It’s wise to schedule your appointment well in advance of important events. At our cosmetic surgery clinic, we tailor a personalized plan for each patient that involves working backward from the target date and implementing measures to minimize risks (such as selecting the injection layer and needle type, applying compression, and cooling).
Disadvantage 4: Individual differences in how the effects are perceived
Everyone’s skin is unique, influenced by factors such as age, UV exposure history, smoking, sleep, skincare habits, and hormonal balance. It’s not guaranteed that you’ll see results comparable to the “before and after” photos on social media.
For individuals with good baseline skin condition, the results may be relatively mild. During a cosmetic surgery consultation, it is important to assess the baseline condition and visualize the achievable outcomes.
Disadvantage 5: Not suitable for adding volume
Since Rituo is not a filler, it is not suitable for directly filling deep nasolabial folds, marionette lines, or areas of volume loss in the temples, forehead, and cheeks. For these concerns, other options—such as hyaluronic acid fillers or fat grafting—may be more appropriate.
In cosmetic surgery, we diagnose the causes of concerns by examining each layer—skin, fat, ligaments, bone structure, and muscle—and combine treatments in a way that is best suited to each specific area.
Disadvantage 6: Not suitable for people who prioritize immediate results above all else
If you’re hoping for immediate results—such as “undergo the treatment today and see a change tomorrow”—this treatment is likely not suitable for you. It’s best suited for those who can enjoy gradual, natural improvements. If you need to achieve short-term goals, it’s standard practice in cosmetic surgery to consider combining this treatment with other procedures.
Disadvantage 7: Ongoing costs
Because the treatment plan involves both initial treatment and follow-up care, certain costs—such as procedure fees, consultation fees, anesthesia fees, and any additional treatments as needed—will accumulate. Rather than choosing a facility based solely on price, you should evaluate it comprehensively, taking into account medication management, hygiene protocols, and the facility’s ability to respond to emergencies.
At our cosmetic surgery clinic, we discuss the balance between cost and expected results (value for money) with you in advance.
Disadvantage 8: The final result depends on the injection technique
Understanding the injection layer, volume, spacing, skin thickness, and site-specific characteristics directly impacts the final result. Experience is essential for ensuring uniformity, avoiding unevenness, and preventing unwanted swelling. In cosmetic surgery, we thoroughly focus on planning based on anatomical principles, optimizing the amount used, and conducting thorough local risk assessments.
Disadvantage 9: There are concerns where a different treatment would be more appropriate
Deep wrinkles (static and dynamic), significant sagging, excess fat volume, hyperpigmentation, and telangiectasia all have different underlying causes. In many cases, other treatments—such as Botox, hyaluronic acid, HIFU, radiofrequency, lasers, or surgical procedures—may be more appropriate.
At our cosmetic surgery clinic, we begin by diagnosing the cause and then propose the most direct treatment strategy.
Side Effects, Contraindications, and Risk Management from a Cosmetic Surgery Perspective
Common Transient Reactions
Redness, swelling, bruising, pain, discomfort, itching, and unevenness at the injection site usually subside within a few hours to a few days. You can reduce the risk by avoiding strenuous exercise, bathing, alcohol consumption, and massage for 24 to 48 hours.
At our cosmetic surgery clinic, we provide detailed instructions on self-care procedures for the 48 to 72 hours following surgery.
Rare but Important Complications and Early Intervention
Although infections, inflammation, lumps, and allergic reactions are rare, they are not impossible. If you experience symptoms such as redness, worsening pain, a sensation of heat, purulent discharge, or widespread swelling, you should seek medical attention promptly.
In cosmetic surgery, we minimize risks by implementing strict hygiene protocols (aseptic techniques), proper management of drug lots, and a system for postoperative communication and follow-up.
Pre-Treatment Checklist (Contraindications and Concurrent Medications)
- As a general rule, women who are pregnant or breastfeeding should refrain from participating.
- Avoid areas with active dermatitis or infection
- Be aware of the risk of internal bleeding while taking anticoagulants or antiplatelet medications (consult your prescribing physician).
- Please disclose any history of severe allergies in advance.
- Adjusting the interval between treatments and recent intense procedures (deep peels, high-power lasers)
In cosmetic surgery, safety parameters are established based on a patient’s medical history, current medications, and allergy information.
Indications and Contraindications for Cosmetic Surgery, and How to Manage Patient Expectations
People Who Aren't Suited for This
- Expecting a dramatic change after just one session
- Its main purpose is to add volume
- Aiming to fundamentally improve deep wrinkles and severe sagging
- When there isn't much time, such as the day before an event
- I do not wish to continue maintenance
Suitable for
- For those seeking natural rejuvenation and an overall improvement in skin quality
- You can aim to improve firmness, radiance, and dry fine lines
- Open to gradual changes and proactive about ongoing care
- They prioritize a natural, bare-skin look and prefer changes that go unnoticed by those around them
Goal Setting and How to Interpret "Before & After" Data
Clarifying evaluation criteria that are easy to experience firsthand—such as “reduced visibility of pores,” “makeup application,” “cheek radiance,” and “reduced dryness”—will increase the sense of conviction. Since “Before & After” images can look different depending on lighting, angle, and skin condition (whether or not the skin is moisturized), be sure to verify that the conditions are consistent.
In cosmetic surgery, we use a combination of objective metrics (imaging protocols, skin measurements) and subjective evaluations to visualize progress.
Differences from Other Skin Boosters and Treatments, and Strategies for Combining Them
Differences from Hyaluronic Acid Fillers
There is a clear distinction between the two: fillers excel at structural volume correction, while Rituo excels at improving skin texture, radiance, and subtle changes in texture. It makes sense to use fillers for contouring and improving deep furrows, and Rituo for enhancing the natural texture of the skin. In cosmetic surgery, we design a treatment plan that takes into account the overall harmony of the face.
Division of Roles Among Botox, HIFU, RF, and Lasers
Botox is ideal for expression lines; HIFU and RF are effective for sagging skin and contour tightening; and lasers excel at treating uneven skin tone and redness. Rituo does not compete with these treatments but rather enhances the foundation—skin quality—to provide a solid base for the overall results. The strength of cosmetic surgery lies in its ability to layer treatments according to specific goals and combine them in just the right balance—neither too much nor too little.
Approaches to Combination Use (Examples)
- Short-Term Goal: Use a low-power laser and Rituo to enhance skin clarity and radiance
- Mid-term goal: Use Botox to reduce dynamic wrinkles while maintaining skin texture with Rituo
- Structural Correction: Use filler to fill only the necessary areas, and use Retuo to adjust the surface texture.
Over-treatment can be counterproductive. In cosmetic surgery, we design a treatment plan based on a three-pronged approach: your goals, budget, and tolerance for downtime.
The Treatment Process and Tips for Reducing Downtime
Preparations
- Avoid supplements and alcohol that promote blood circulation before and after drinking
- Strengthen sun protection and moisturization, and restore the skin barrier
- Standardize photography guidelines and visualize changes through "Before & After" images
Schedule for the Day
Cleansing → Anesthesia (if necessary) → Injection Design → Injection → Compression and Cooling → Explanation of Aftercare Instructions. In cosmetic surgery, we ensure both uniformity and safety by taking into account the skin thickness and blood vessel distribution in each area.
Postoperative Care and Things to Avoid
- On the day of the procedure, avoid strong friction, heat exposure, saunas, and strenuous exercise.
- Thoroughly moisturize and protect against UV rays to support the skin’s barrier function
- In case of an emergency, do not try to handle the situation on your own; contact us or seek medical attention as soon as possible.
The quality of your self-care directly affects your recovery time and satisfaction. Be sure to keep all instructions provided by the cosmetic surgery clinic, and consult with them if you have any questions.
Key Considerations When Choosing a Cosmetic Surgery Clinic
The Doctor's Experience and Transparency in Before-and-After Results
Knowledge of anatomy, experience with injections, and a proven track record in managing complications are crucial. When reviewing “Before & After” photos, look for those that clearly specify the shooting conditions and the time elapsed since the procedure. The ability to show “Before & After” photos of similar concerns during the consultation is also an indicator of trustworthiness.
Not Just Price, but Safety Management and Accountability
The storage and lot management of medications, the use of disinfectants and disposable supplies, emergency response protocols, and postoperative communication systems form the foundation of a cosmetic surgery practice. Be sure to confirm that the clinic explains any uncertainties, limitations, and potential side effects.
List of Questions to Discuss During Counseling
- Why is Rituo the right choice for my concerns? (Comparison with other options)
- Estimated Number of Sessions, Frequency, and Cost to Reach the Goal
- Expected Downtime and Actions to Avoid
- Procedure for Handling Rare Complications
- Shooting Conditions and Evaluation Metrics for "Before & After" Photos
If you choose a cosmetic surgery clinic that provides consistent answers to these questions, you can expect a highly satisfying outcome.
Summary
Re2O is a skin booster that focuses on enhancing the overall texture of the skin. On the other hand, some of the drawbacks of Re2O include “it’s difficult to achieve dramatic results with a single treatment,” “it requires multiple sessions and ongoing maintenance,” “there is some downtime,” “results vary by individual,” “it is not suitable for volume correction,” “it is not the right choice for those prioritizing immediate results,” “it involves ongoing costs,” “the final results depend on the practitioner’s skill,” and “other treatments may be more appropriate for certain concerns.” It is important to understand these points in advance.
The key is not to choose a “popular treatment,” but to make a choice that suits your specific concerns, timeline, budget, and lifestyle. A thorough consultation at a cosmetic surgery clinic, setting realistic goals, and viewing transparent “before and after” photos are the surest path to results you’ll be satisfied with. By accurately understanding the pros and cons of Lituo and making your decision after a thorough consultation, you’ll steadily move closer to your goal of achieving a natural, youthful appearance.
Finally, medical care is based on the principle of individualized treatment. This article is intended to provide general information and is not an advertisement for any specific product or facility. Please make your final decision after a face-to-face consultation at a reputable cosmetic surgery clinic, and feel free to ask any questions you may have. That is the first step toward making a decision you won’t regret.
Summary: Re2O is a skin booster designed to improve skin texture, making it an ideal treatment for those who wish to naturally enhance firmness, radiance, skin texture, and reduce fine lines caused by dryness. However, there are also drawbacks you should understand in advance, such as the fact that dramatic results are unlikely after a single session, the need for multiple treatments and regular maintenance, and the risk of downtime and side effects. Furthermore, Re2O alone may not provide sufficient improvement for deep wrinkles, severe sagging, or loss of volume; in many cases, it is best combined with other treatments such as hyaluronic acid, Botox, radiofrequency, or HIFU.