column (e.g. in newspaper)
2024.06.30
What are the side effects of isotretinoin? Dr. Senki Akashi of Bianca Clinic explains how to manage them [with case examples]
With deep medical insight cultivated as an internal medicine specialist, I bridge aesthetic surgery, dermatology, and internal medicine. Having spent my childhood in China, I communicate fluently in Japanese, Chinese, English, and Korean. Possessing an international perspective—evidenced by invitations to present at overseas conferences—I actively promote techniques as a Key Opinion Leader (KOL) for GOURI and REJURAN®. My specialty procedures include double eyelid surgery, skin-nurturing boosters, and body hyaluronic acid treatments. My approach leverages the holistic understanding of the body cultivated through internal medicine to guide patients toward natural, healthy beauty.
Hello, everyone. I'm Dr. Hime from BIANCA CLINIC, also known as Senki Akashi.
"Isotretinoin seems to work well, but I'm worried about the side effects..."I often hear that kind of thing.
While isotretinoin is indeed a medication that can be expected to have excellent effects for improving acne, it also comes with precautions such as dryness and potential effects on liver function.
This time, we'll explain the common side effects of isotretinoin and how to manage them.
I hope this serves as an opportunity to deepen your knowledge and understanding.
BIANCA Akashi Senki, MD Profile
Spent childhood in China and is trilingual in Chinese, Korean, and Japanese. After graduating from Nagoya University School of Medicine, she specialized in internal medicine with a focus on diabetes and endocrinology, becoming a board-certified internist. Subsequently, she gained experience performing over 5,000 surgical procedures and injectable treatments at a major cosmetic surgery clinic, later serving as director of a clinic in central Tokyo. She specializes in eye area surgeries, particularly double eyelid suture procedures and dark circle treatments. Currently at BIANCA Clinic, he supports patients in achieving a naturally beautiful glow from the inside out, encompassing all aspects of cosmetic surgery, medical aesthetics, and cosmetic dermatology.
＜Professional Affiliations and Qualifications＞
・Japanese Society of Internal Medicine Board-Certified Internist
・Japanese Diabetes Society
・Japanese Society of Aesthetic Plastic Surgery
・Japanese Society of Anti-Aging Medicine
＜Check out more information about Dr. Akashi Senki's Aesthetic Medicine here＞
Dr. Akashi Senki's Instagram account isHere
The official Instagram account for BIANCA isHere
The official YouTube account for BIANCA isHere
Isotretinoin: The Ace Up Your Sleeve for Acne Treatment
"Just when I thought it was cured, another one pops up right next to it..." "Even with ongoing insurance-covered treatment, it just won't improve..."
For such stubborn acne, the highly effective solution isIsotretinoinis.
Isotretinoin is an oral medication whose main ingredient is a vitamin A derivative. It suppresses sebum production to address the root cause of acne.
Although it is a treatment strongly recommended by the American Academy of Dermatology (AAD), in Japan it is not covered by insurance due to concerns about side effects and is only available as a self-pay treatment.
Common Side Effects of Isotretinoin and How to Manage Them
Isotretinoin is a highly effective medication, but because it carries risks of side effects, it is important to understand and use it correctly.
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Dryness (nose, eyes, lips)Almost guaranteed to occur. Perform daily moisturizing care using petroleum jelly, moisturizing lip balm, artificial tears, etc.
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Effects on Liver Function and Lipid MetabolismElevated cholesterol or triglyceride levels may occur. Since this can only be determined through blood tests,Regular blood testsis required.
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Joint pain, muscle pain, headaches, etc.→ These symptoms are often temporary, so take it easy and pace yourself according to how you feel.
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Risk of Depression and Suicidal Ideation→ While a clear causal relationship has not been proven, individuals with mental health concerns should take particular caution. During treatment,Be sensitive to changes in your mood and share them with your doctor.is important.
Can I take isotretinoin while trying to conceive or during pregnancy?
Isotretinoin hasStrong teratogenicityTherefore, it cannot be taken during pregnancy, nor by those trying to conceive.
Furthermore, a contraceptive period is required even after stopping the medication.
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Women: 6 months
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Men: 2 months
This point must be strictly adhered to.
How Much Does Acne Improve with Isotretinoin? Case Photos Introduced
At Bianca Clinic, we offer an acne treatment method combining HydraFacial with isotretinoin (Roaccutane).
Finally, let's take a look at before-and-after photos of actual patients who took isotretinoin.
※Roaccutane is the international trade name for a medication containing isotretinoin as its main ingredient. The active ingredient itself is identical; in Japan, it is handled as a self-pay treatment under the name “isotretinoin.”
Top: Before treatment / Bottom: 1 month after starting treatment
💴 HydraFacial 6 sessions / Roaccutane 3-month supply ¥198,000
⚠️ Side effects such as dry skin and mucous membranes may occur.
Top: Before treatment / Bottom: 3 months after starting treatment
💴 HydraFacial 6 sessions / Roaccutane 3-month supply ¥198,000
⚠️ Side effects such as dry skin and mucous membranes may occur.
※Please note that effects and side effects may vary from person to person.
Summary: Use isotretinoin with an understanding of its side effects.
Isotretinoin is a powerful medication that can serve as a “last resort for acne treatment” when precautions against side effects are followed.
Taking measures against dehydration, undergoing regular blood tests, receiving mental health support, and adhering to contraceptive rules—it's crucial to keep these points firmly in mind and work closely with your doctor.
At Bianca Clinic, we support acne treatment using isotretinoin, tailored to each patient's physical condition and lifestyle.
If you're interested, please feel free to contact us anytime.
Acne Treatment Professional! Be sure to also check out Dr. Aya Hayama's blog here▼
https://biancaclinic.jp/blog/43860/
This one is also very easy to understand.▼
https://biancaclinic.jp/blog/44290/
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