ヒアルロン酸注射で加齢にともなうボリュームロスを改善 | 日本を代表する美容健康再生医療のクリニック

BLOG

column (e.g. in newspaper)

2025.08.15

Hyaluronic acid injections improve volume loss associated with aging

Supervising Physician

Aiya Hayama

As an Assistant Professor, Associate Ward Director, and Chief of Dermatopathology at the university hospital dermatology department, I deepened my expertise through academic presentations and paper publications both domestically and internationally. I have handled a wide range of treatments, from birthmark therapy in children to adult pigmentation concerns, utilizing various lasers and injection therapies, while also contributing to community healthcare. Through encountering numerous cases, I strongly felt the potential and necessity of aesthetic medicine, resolving to pursue further expertise. Building upon my solid dermatological knowledge and meticulous diagnostic skills, I value treatments that gently support each individual's skin while bringing out its inherent beauty.

When you hear "hyaluronic acid injections," many people probably imagine a face with strong volume, like a "hyaluronic acid face." Here, we introduce a method to achieve natural rejuvenation by using hyaluronic acid injections to address volume loss associated with aging.

I am Dr. Aya Hayama, a board-certified dermatologist.

Hyaluronic Acid Injections for Rejuvenation

Hyaluronic acid injections involve directly injecting cross-linked hyaluronic acid into the target area using a syringe, rather than the non-cross-linked hyaluronic acid formulations used in skin care.Treatments for wrinkle improvement, facial contouring, and other proceduresis.

The purpose is to improve areas that have lost volume due to aging through the injection of hyaluronic acid, and to improve the associated sagging (nasolabial folds and marionette lines).

Hyaluronic acid is a substance naturally present in the body, offering the advantage of minimal risk of side effects or allergic reactions from injections. The duration of its effects varies by formulation but generally lasts approximately 6 months to 2 years. While hyaluronic acid injections are relatively easy to try, the procedure's outcome and effectiveness are significantly influenced by the skill of the treating physician.

While considering the overall balance of the patient's face, it is necessary to adjust not only the injection sites and volume but also the type of hyaluronic acid and the injection technique.

The appeal lies in its ability to transform your look dramatically, from subtle changes to significant makeovers.

Representative Hyaluronic Acid

【Juvederm Vycross Series】

ヒアルロン酸注入

“A series hailed as ”the world's highest-grade hyaluronic acid."

Its smooth finish is appealing, with effects lasting over a year. Another key feature is how high-molecular and low-molecular hyaluronic acids efficiently bind together without gaps. Its ease of injection and shaping now enables volume enhancement in the lips and around the mouth—areas previously difficult with conventional formulations.

【Restylane/Restylane Lift】

ヒアルロン酸注入

A hyaluronic acid formulation with numerous case results worldwide.

Restylane was the first non-animal-derived stabilized hyaluronic acid injectable to receive approval from the U.S. FDA and is also approved by the Japanese Ministry of Health, Labour and Welfare.

Injections are possible in various areas such as the eye area, temples, cheeks, around the mouth, and the jawline.

https://biancaclinic.jp/treatment_category/lips/lips_01/hyaluronic/

Changes associated with aging

Primarily, bone and fat atrophy, and the fat-supporting ligaments become lax, leading to volume loss (hollowing) and sagging.

Bone changes

The bones of the upper jaw, lower jaw, and eye sockets gradually resorb, causing the face to lose height and support. This results in sunken cheeks and a loss of jawline definition.

脂Subcutaneous fat and its distribution

Superficial fat atrophies, while deep fat sags or shifts. Additionally, fat infiltration into the dermis occurs, leading to reduced firmness and accelerated wrinkle formation.

Adipose-supported ligament

These fibrous structures anchor and support facial fat, skin, and soft tissues to deep structures (bone and fascia). The presence of these ligaments keeps each facial feature in its proper position, maintaining a youthful contour.

Ligament laxity

The supporting force for fat weakens, causing fat pads to sag and shift position.、Nasolabial folds and marionette lines become deeper.

The "boundary" formed by ligaments is emphasized

In areas where the supporting ligaments are strong, the skin remains firm, while the surrounding areas sag, resulting in a distinct line.

Adipose tissue atrophy around ligaments

The jawline and hollow cheeks become more pronounced, creating an aged appearance.

This is injected into areas with volume loss on the forehead, temples, and cheeks.