column (e.g. in newspaper)
2025.09.10
What are the effects of high-concentration glutathione IV therapy? It's not just about skin whitening!
As an Assistant Professor, Associate Ward Director, and Chief of Dermatopathology at the university hospital dermatology department, I deepened my expertise through academic presentations and paper publications both domestically and internationally. I have handled a wide range of treatments, from birthmark therapy in children to adult pigmentation concerns, utilizing various lasers and injection therapies, while also contributing to community healthcare. Through encountering numerous cases, I strongly felt the potential and necessity of aesthetic medicine, resolving to pursue further expertise. Building upon my solid dermatological knowledge and meticulous diagnostic skills, I value treatments that gently support each individual's skin while bringing out its inherent beauty.
Have you heard of high-concentration glutathione IV therapy?
In recent years, this IV therapy—also known as "White Pearl IV"—has gained attention in the entertainment industry, beauty clinics, and among health-conscious individuals for its skin-whitening and anti-aging benefits. Furthermore, it offers health advantages such as liver function support and fatigue recovery, making it a recommended IV therapy for those seeking to combine beauty and wellness.
This time, I'd like to write about how high-concentration glutathione IV drips work, their effects, how often to receive them, whether there are side effects, and who they're actually recommended for.

I am Dr. Aya Hayama, a board-certified dermatologist.
High-concentration glutathione IV drip
Glutathione is present in the body.Powerful antioxidantsSo,It has the function of removing active oxygen and protecting cells.。
Increased by ultraviolet rays, stress, smoking, and alcohol consumptionReactive oxygen species not only cause dark spots, wrinkles, and dull skin, but also significantly contribute to aging and fatigue.I will do so.
Glutathione is an essential component for detoxification in the liver, playing a role in helping to eliminate alcohol and harmful substances.has also been achieved.
However, glutathione levels in the body decrease with aging and poor lifestyle habits. For this reason, high-concentration glutathione IV therapy—which delivers high-concentration glutathione directly into the body via IV—is gaining attention not only for beauty but also as a method for maintaining health.
Effects of High-Concentration Glutathione IV Therapy
High-concentration glutathione IV therapy is expected to deliver a wide range of benefits, from cosmetic purposes to overall health maintenance.
First,skin-whitening effectRegarding...Glutathione suppresses melanin production.It improves dark spots and dullness, leading to more translucent skin. For this reason, it is sometimes called the "White Pearl IV Drip." Another great benefit is that, precisely because it's an IV drip, it works on the skin all over your body.
Anti-aging effectsasIts powerful antioxidant properties help prevent cellular oxidation and are expected to support the prevention of wrinkles and sagging.Yes, it can. Recommended for those concerned about skin changes due to aging.
Additionally, the high-concentration glutathione IV drip containsGlutathioneis,A tripeptide formed by the combination of the amino acids glutamic acid, cysteine, and glycineThe amino acids that make up glutathione have the following functions.
■Glutamic AcidSupports growth hormone and boosts immunity
■Cysteine:Inhibits melanin production
■GlycineSupports collagen production and leads to beautiful skin
These peptides are present in high concentrations within cells, particularly in the liver,Its ability to support liver function is also drawing attention.
The liver is inherently prone to oxidative stress as it performs detoxification and metabolic functions. It reduces reactive oxygen species using glutathione, protecting cells from oxidative damage. Furthermore, since fat-soluble toxins and drugs cannot be excreted in their original form, they undergo a metabolic process called glutathione conjugation in the liver. This converts them into water-soluble compounds, facilitating easier excretion.
Therefore,People who drink alcohol frequently or have unbalanced diets tend to put strain on their livers, but glutathione IV drips help support detoxification and can also alleviate hangovers and fatigue.。
In addition,For those experiencing chronic fatigue or leading stressful livesIt is being used. It supports energy metabolism from within the body and is expected to help restore vitality.
Treatment Method
High-concentration glutathione IV therapy is administered via intravenous drip into an arm vein after a physician's consultation. The procedure takes approximately 20 to 30 minutes, making it convenient to schedule during breaks from work or shopping.
Results may vary from person to person,For cosmetic purposes, it is often recommended to continue treatments once a week to several times every other week, followed by monthly maintenance thereafter.For improving liver function or recovering from fatigue, continuing regular treatments will help you feel the effects more readily.
Side effects and precautions
High-concentration glutathione IV therapy is a relatively safe procedure, but the possibility of side effects is not zero.
Depending on your constitution, you may experience symptoms such as rashes, headaches, or nausea. Those with allergies should be especially cautious.
Additionally, since the way effects appear varies from person to person, it's important not to place excessive expectations on immediate results, such as "your skin will instantly become fairer" or "fatigue will disappear after just one use."
If you wish to live a beautiful and healthy life every day, consider high-concentration glutathione IV therapy as one of your options.
Additionally, BIANCA CLINIC employs board-certified aesthetic medicine specialists who are directors of the Aesthetic Medicine Society and possess deep expertise in world-class aesthetic medical treatments. We therefore offer a wide range of aesthetic medical treatment options, including high-concentration glutathione IV drips, enabling us to provide high-level aesthetic medical treatments!
https://biancaclinic.jp/treatment/skin-care/skin/glutathione/