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2025.11.13

Explained by a Cosmetic Physician! BIANCA's IV Therapy Summary

横山 歩依里
Supervising Physician
Ayori Yokoyama

My journey into aesthetic medicine stems from a desire to help enrich and beautify lives beyond simply treating illness. My specialties include hyaluronic acid, Botox, and thread lifts. I provide treatments that enhance each individual's unique qualities and bring out an elegant, natural beauty. For concerns around the eyes that are difficult to improve with dermatology alone, I also perform surgical procedures. By integrating dermatology and surgery, I holistically balance the entire face. With three periods of overseas study, I am also able to provide consultations in English.

Hello!

I am Ayuri Yokoyama, a cosmetic dermatologist and plastic surgeon.
I am also a member of the Society of Aesthetic Medicine.

 

 

 

IV therapy that enhances beauty and resilience from within the body.
BIANCA also offers a wide range of IV drip menus, each with its own distinct features and purposes.

In this article, we'll carefully explain from an expert's perspective what works and how, and which concerns it addresses!

 

 

 

1. Why We Recommend IV Therapy

  • Delivers a high concentration of active ingredients in a single application(can achieve higher blood concentrations than oral administration)

  • Enhances recovery after treatments and boosts skin's foundational strength

In particular,

  • Repairing UV damage

  • Dullness improvement

  • Reduces fatigue and skin stress

  • Boosting antioxidant capacity  is useful.

 

 

2. Popular IV Drip Menus at BIANCA

① High-concentration Vitamin C IV Drip

PurposeAntioxidant, skin brightening, fatigue recovery
Suitable for
Dullness, rednessFor those who are concerned about
FatigueThose who have accumulated
When sunbathing or laser treatmentsBefore and after treatment

② High-concentration glutathione IV drip

PurposeAntioxidant, liver function support, detoxification
Suitable for

whiten the skinI want to,transparencyFor those who want
Those who frequently drink alcohol
FatigueThose who have accumulated

③ BIANCA Shot
Choose from five types of beauty injections: whitening, skin roughness, weight loss, fatigue recovery, and hangover relief.

Suitable for

・For those seeking a quicker procedure (since it's administered via injection rather than IV drip, the treatment time is shorter)

・For those who want to continue casually and frequently

 

3. Regenerative medicine IV drips are also popular.

BIANCA also offers numerous intravenous treatments for regenerative medicine.
It is very popular among beauty enthusiasts seeking anti-aging benefits.

④ Exosome Infusion

● What are exosomes?

These are micro-particles secreted by cells, acting like "information capsules" that contain growth factors, cytokines, microRNAs, and other substances.

Within the body, exosomes are released from various cells, supporting tissue repair and regeneration while transmitting information.
However, as the number of stem cells decreases with age, the secretion of exosomes also declines accordingly.

Therefore, by supplementing the reduced exosomes through exosome injection, which replenishes exosomes from outside the body.
By supporting the activation of somatic stem cells throughout the body,Anti-inflammatory effects and tissue repair effectscan be expected.

● Expected Effects

  • Suppress inflammation

  • Skin Repair Support

  • Whole-body rejuvenation

  • Fatigue and Stress Reduction

 

⑤ Stem cell culture supernatant

Not the stem cells themselves, but substances secreted during the culture process

Growth factors, cytokines, exosomes
This is the supernatant, which includes [etc.].

Autologous Stem Cell Infusionand also,Costs may increase, but the effectiveness is far greater.
This stem cell therapy is gaining attention for its potential to promote the repair of tissues damaged by aging, improve blood flow, and suppress inflammation by administering the patient's own new stem cells.

● Expected Effects

  • Restoration of the barrier function

  • Soothing skin redness and inflammation

  • Reduced downtime

  • Fatigue recovery

  • Whole-body rejuvenation

 

💡 ④⑤'sPoints
To experience the effectsContinuation is essential
Evidence is increasing, but individual differences in effectiveness are significant.
Individuals with a history of cancer are contraindicated.

 

 

 

⑥ NMN IV Drip, NAD+ IV Drip

● What is NMN?
→Components that are converted to NAD+

NMN is a component found within the cells of all living organisms.

Decreased levels of NMN in the body are thought to be one cause of the onset of aging and the progression of cognitive and physical decline.

Furthermore, in recent years,NAD+ is also involved in activating the sirtuin genes (longevity genes) that govern aging.I've come to understand what they're doing.

Humans have seven types of sirtuin genes, and NAD+ is said to activate all of them!!

● Expected Effects

  • Supports energy metabolism

  • Fatigue recovery

  • Improving Sleep Quality

  • Improving skin metabolism

  • Preventing Decline in Physical Strength

NMN is one of the most advanced fields in anti-aging research,
especially those in their 40s and older Reduced metabolism and accumulated fatigue It's also popular among those who are aware of it. ☺

 

💡How to Use NMN and NAD+ IV Drips

Due to NAD+'s large molecular weight, which makes it difficult for cells to absorb directly, it has been common practice to supplement with NMN, which has a smaller molecular weight, via intravenous drip.
NMN intravenous therapy exerts its effects gradually because it undergoes a process of conversion into NAD+.
However, as research progressed and a pathway was identified that allows the large NAD+ molecule to be directly absorbed, NAD+ infusion therapy emerged.
Since NAD+ is administered directly, there is no conversion process involved, so effects tend to be felt more quickly.
On the other hand, NAD+ IV therapy may cause some individuals to feel unwell during the treatment.
For immediate results, NAD+ is recommended; for safety and peace of mind, NMN is recommended.

 

4. Important Notes

  • The IV drip is strictly "Adjuvant Therapy"

  • The tangible effectThe frequency of treatment, lifestyle, and whether it's combined with other skin treatments can significantly affect the results.

  • Exosome and stem cell supernatant therapies show some bias in evidence within private medical care.

  • Within regenerative medicine,NMN has a relatively long history, and research on its metabolic benefits is well advanced.Many aspects remain unexplained.

 

5. Summary

BIANCA's IV therapy is,
A highly synergistic menu that enhances the effectiveness of skin treatments while supporting the body's overall recovery, metabolism, and antioxidant defenses.is

In particular,

  • Maximize the effectiveness of skin treatmentsI want to make them do
  • Not only the skinWhole-body anti-agingI want to do it

  • Fatigue and stressis prone to appearing on the skin

  • Transparency and resilienceI want to raise it more

It's also highly recommended for those who...☺

There's more to discuss than can be covered here, so if you're interested, please feel free to come in for a consultation.

 

 

 

We are currently running an Embrace Campaign.

Details here↓

https://biancaclinic.jp/recommend/45299/

If you're interested, please feel free to come in for a consultation.
We warmly welcome you to visit our clinic for counseling alone.

 

 

Reservations can be made here.

Complete your reservation in 60 seconds ▶︎

 https://reservation.medical-force.com/b/d7bb811e-ebd5-4b93-93f8-588864b24f15

 

【Profile】

Plastic Surgeon/Cosmetic Dermatologist Dr. Ayuri Yokoyama

Japan's Leading Clinic for Beauty and Health Regenerative Medicine|BIANCA CLINIC GINZA/OMOTESANDO 

In my previous role, I was involved in establishing a clinic as a cosmetic dermatologist, from its inception to opening, and served as its director for three years.
Having worked with approximately 20,000 patients' skin and faces, contributing to the clinic's development.

To further expand the scope of treatment, I have now transitioned to BIANCA CLINIC, a leading aesthetic and regenerative medicine clinic in Japan.

We provide the latest aesthetic medical treatments for well-aging, encompassing not only cosmetic dermatology but also cosmetic surgery and internal medicine.

 

【Career】

2020 Graduate of the School of Medicine, Hiroshima University

2020: Worked at JCHO Tokyo Shinjuku Medical Center and affiliated hospitals (National Center for Global Health and Medicine Hospital, Tokyo Yamate Medical Center)

2022: Joined ELM Medical Corporation Served as Director of Azabu Clinic

2025: BIANCA joins the company

【Professional Affiliations/Qualifications】

The Japanese Society of Aesthetic Dermatology

Japanese Society of Anti-Aging Medicine

Occupational Physician Certification

【SNS】

Instagram account 

https://www.instagram.com/dr.airi

 

 

 

 

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