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2025.07.04

Mesona J: The Ultimate Skin Treatment!!

葉山 愛弥
Supervising Physician
Aiya Hayama

As an Assistant Professor, Associate Ward Director, and Chief of Dermatopathology at the university hospital dermatology department, I deepened my expertise through academic presentations and paper publications both domestically and internationally. I have handled a wide range of treatments, from birthmark therapy in children to adult pigmentation concerns, utilizing various lasers and injection therapies, while also contributing to community healthcare. Through encountering numerous cases, I strongly felt the potential and necessity of aesthetic medicine, resolving to pursue further expertise. Building upon my solid dermatological knowledge and meticulous diagnostic skills, I value treatments that gently support each individual's skin while bringing out its inherent beauty.

Hello! It's that time of year when many people experience skin irritation due to hot days, air conditioning, pollen, and sweat. When your skin isn't feeling its best, try Mesona J!

I am Dr. Aya Hayama, a board-certified dermatologist.

 

Today, I'd like to introduce Mesona J—a guardian against such UV-related issues and various other skin troubles, and what could be called a universal beauty treatment.

When applying cosmetics to your skin, do you ever wonder if they truly penetrate it?

The skin is the largest organ, and it's actually problematic if everything and anything from the outside were to pass through.

Thus, the skin acts as a barrier against external substances,Physical keratinand,Charge ions to create a barrieris doing.

Ion introduction, a technology well-known to many, uses electrical power to permeate specific ionized beauty serums.

 

Mesona J

Mesona J is the world's first transdermal delivery device designed exclusively for medical institutions to meet stringent quality standards required for medical devices (JIS standards, EMC testing, etc.).

Additionally, Mesona J inherits all the functions of the renowned Italian-made "Mesactis," a transdermal delivery device exclusively for medical institutions, while offering higher quality and superior performance.Domestic transdermal delivery deviceas well.

Unlike iontophoresis devices or ultrasonic delivery devices, Mesona J features mesoporation technology, which utilizes electroporation.

Electroporation is a technique that uses specialized electrical pulses to create microscopic gaps in the skin cell membrane.

By this method,It can simultaneously deliver multiple components—such as non-ionized ingredients and high-molecular-weight active ingredients that do not penetrate simply by application—deep into the dermis without causing pain.That's it!

Mesona J delivers active ingredients to the dermal layer without damaging the skin, acting directly on cells to produce results comparable to injection methods. Through Mesoporation, the principle behind Mesona J,The penetration power of active ingredients into the skin is approximately 300 times greater than with regular application and about 70 times greater than with iontophoresis devices.It is also said to be uploaded.

Mesona J treatment involves two steps. First, electroporation is performed using a pen-shaped probe to create pathways for delivering active ingredients into the dermis. Next, a roller-shaped probe is applied to the skin, using electrostatic repulsion, electroosmosis, and physical pressure to introduce active ingredients into the dermis without causing skin damage or pain. Any small gaps created in the cell membranes close immediately, so there is no need for concern.

The greatest advantage of Mesona J is its ability to penetrate deep into the skin.

 

Her appearance while performing the treatment is also cute.

 

The medications used vary, but we combine the appropriate active ingredients from the following eight types based on your skin concerns and preferences.

At BIANCA CLINIC, we address all skin concerns, including melasma, dark spots, wrinkles, dullness, enlarged pores, loss of firmness, and skin whitening.THE PINK

Primarily for concerns about liver spots, dark spots, and achieving a translucent complexionTHE WHITE

We have selected and introduced the following agents.

1) Vitamin C Derivative: Effective for wrinkles, dark spots, and anti-aging care. Boosts collagen production for firmer, more translucent skin.
2) Tranexamic acid: Particularly effective for melasma. It may also help suppress inflammation.
3) Arbutin: Expected to improve post-inflammatory hyperpigmentation and provide whitening effects.
4) Argireline: Effective for wrinkles. Also known as "topical Botox."
5) Hyaluronic Acid: Effective for anti-aging care and enhancing skin hydration. It refines skin texture and promotes firm, radiant skin.
6) Vitamin A: Effective for enlarged pores, acne, and anti-aging care. Prevents photoaging and promotes firm, resilient skin.
7) Vitamin B12: Useful for redness of the face and atopic dermatitis
8) Vitamin B6: Supports skin turnover and helps eliminate dead skin cells and clogged pores.

MESONA-J (MESOPORATION) | Japan's Leading Clinic for Aesthetic and Regenerative Medicine | BIANCAGINZA

 

Mesona SA

And a high-quality, high-performance Japanese medical-grade skincare brand developed by dermatologist Dr. Iwama (I wish I could say it was mine, but honestly, it's amazing 👏)『SkinAmure』

Among them is Dr. Iwama's high-concentration vitamin serum, developed over five years without compromise. It guides skin toward a clear, worry-free radiance and serves as a protective guardian for your complexion.SASERUM"Mesona SA" utilizes Mesona J technology, delivering a revolutionary skincare treatment that combines high-quality, high-performance serum "SkinAmure SASERUM" with tranexamic acid and EGF (Epidermal Growth Factor) to deeply nourish the skin.

【Dr. Iwama's Profile】

This treatment also addresses various skin concerns such as melasma, dark spots, wrinkles, redness, acne scars, dullness, and enlarged pores. After the session, you'll notice improved skin tone and texture.

Even stubborn redness is effectively improved through treatment!! (Using the high-performance skin diagnostic device: VISIA)

 

Of course, Mesona J involves minimal pain and downtime during treatment, making it suitable even before important events or during therapeutic* procedures.

*Therapeutic … A 3-4 month intensive skin improvement program using ZeoSkin Health products from Doctors Cosme.

 
Here's a personal musing from me, a dermatologist...

Even when you think your skin is in good condition, Mesona J always delivers even better results—I'd want to get it done at least once a week.

Cosmetic medicine is recommended even for those who want to try it but are hesitant about injections or surgery!!

Even if you have important matters to attend to, feel free to consult us anytime—our solutions are fast-acting.

 

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