ゴウリ(GOURI)

GOURI

GOURI

Supporting collagen production with liquid PCL injection formulations
Natural Lift-Up

  • World's First Liquid Injection Formulation of PCL (Polycaprolactone) for Thread Lifts
  • Naturally spreads at the injection site to lift and firm areas of concern without discomfort
  • Collagen booster enhances skin texture, elasticity, firmness, and radiance.
堀田 和亮
Supervising Physician
board chairman Kazuaki Hotta

Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.

Unique Initiatives at BIANCA CLINIC

Naturally lift sagging skin and wrinkles!
Liquid PCL injection formulation with high diffusion capacity

GOURI is the world's first liquid-type PCL (polycaprolactone) formulation, developed in May 2021*. PCL is one of the components used as the material for threads in thread lifts. By entering the skin's interior, it stimulates fibroblasts, enhances skin tissue, and supports collagen production. It is suitable for concerns such as skin laxity, sagging, loss of elasticity, as well as depressions, wrinkles, and dark circles under the eyes.

Gouri is a liquid formulation with relatively high diffusion properties. Its characteristic feature is that the product naturally spreads at the injection site, resulting in a natural-looking effect with minimal discomfort. At Bianca, treatments are available for facial areas of concern such as the forehead, under the eyes, cheeks, and around the mouth, as well as the neck, décolleté, elbows, and the back of the hands.

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Downtime

DOWNTIME
Redness, swelling, edema, bruising, hives, and puffiness may occur, but these symptoms typically subside over time and often disappear within a few hours to two days.

At Bianca Clinic, we strive to minimize pain and downtime. We meticulously prepare for your comfort, including anesthesia options and carefully selecting needles to reduce pain and internal bleeding, so even those sensitive to pain can undergo treatment with peace of mind.

Recommended for people like this

RECOMMENDED FOR:
I want firm, radiant skin.
I want to improve sagging skin.
Concerned about dark circles and fine lines
I'm concerned about my skin's lack of elasticity.
Achieve both skin nurturing and lifting at the same time
Seeking a natural lifting effect
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RESERVATION
24-hour reception
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Features

CHARACTERISTICS

GOURI is

GOURI is the world's first collagen booster primarily composed of liquid PCL (polycaprolactone). When injected, it stimulates collagen production in the skin, delivering effects such as lifting and tightening areas of concern like sagging and laxity, enhancing firmness and radiance, and reducing the appearance of hollows and dark circles. Its key feature is rapid dispersion throughout the face upon injection, eliminating the need for multiple needle entry points. It also produces virtually no post-injection skin irregularities commonly seen with other skin-enhancing agents.

ゴウリ(GOURI)とは

Stimulates fibroblasts to produce new collagen in the skin

Gouri is a treatment that supports collagen production; the formulation itself does not contain collagen. By injecting Gouri, it stimulates fibroblasts, strengthens skin tissue, and powerfully increases collagen in the skin. Rather than being a treatment where “effects are felt immediately after injection,” it gradually enhances skin thickness and elasticity over about a month, aiming for a lifting effect.

 

The formulation itself spreads rapidly after injection, but its relatively long degradation time ensures sustained support for collagen production over an extended period. Gouli's defining characteristic is its ability to naturally volumize the skin over approximately one month post-treatment, with effects lasting for several months.

線維芽細胞を刺激して肌に新しいコラーゲンを生成

Compared to conventional injectable formulations, it has lower risk and higher safety.

Conventional injectable formulations sometimes caused side effects such as granulation tissue formation or embolism due to microparticles blocking blood vessels. However, Gouri is liquid with high diffusion properties, minimizing these risks and allowing injection into any facial area to address concerns.

 

Gouri underwent safety testing by North American Science Associates (NAMSA) in 2018, completed clinical trials in Korea for KFDA* approval, and obtained CE marking* in 2021. These certifications are another source of reassurance.

 

* KFDA…The former name of the Ministry of Food & Drug Safety (MFDS) in Korea, referring to the Korea Food and Drug Administration.
* CE Marking... This mark indicates that a product complies with the essential requirements of the relevant directives, which are European Union regulations established by the European Commission (EC) under the New Approach Directive. These requirements cover aspects such as the protection of user health and safety.

従来の注入製剤と比較してリスクが低く安全性が高い

Benefits

MERIT

Achieve a natural lifting effect

Gouri is a treatment whose effects gradually appear over approximately one month after injection, making it popular among those who prioritize natural, gradual changes without forcing results.

No need to repeatedly insert the needle

Because it's a liquid, it spreads quickly across the entire face after injection, eliminating the need for multiple needle pricks—another appealing feature.

The effects last longer due to enhanced collagen production

Gouri has a relatively long degradation time within the skin, so its effects—including a lifting effect from collagen production, firmness, and radiance—are expected to last for several months.

Recommended Features

RECOMMENDED POINTS

Noticeable changes with injections of 2 cc or more

To fully experience the skin changes and effects of Gouri, we recommend injecting at least 2cc of the formulation. Since Gouri itself does not contain collagen, the treatment aims to gradually and naturally achieve skin elasticity and lifting effects over the course of one month following injection, rather than producing visible changes immediately after the procedure. While the degree and duration of effects vary from person to person, Bianca recommends three treatments spaced three months apart. After that, we advise consulting with your physician before resuming treatments, typically after one year has passed. Please consult with us each time.

Not just the face, but also the décolletage, elbows, and backs of the hands.

Gouri is more effective for skin that has lost firmness and shows increased sagging due to years of irritation and UV exposure, or for skin concerned with “etched wrinkles” that deepen with age, rather than skin with significant volume loss. Liquid PCL rapidly spreads to assist collagen production, enhancing skin firmness, radiance, and elasticity while addressing laxity, sagging, wrinkles, and roughness. Gouri can also be injected in areas beyond the face, such as the décolleté showing signs of aging, or rough elbows and hands.

For enlarged pores and crater-like acne scars, Dermapen 4 injections are the ideal approach.

Our clinic also offers Gouri injections using the Dermapen 4. The Dermapen 4 is a pen-shaped device with 16 ultra-fine needles at its tip. It creates micro-channels in the skin to stimulate the body's natural healing response. Combining Gouri with Dermapen 4 facilitates the delivery of cosmetic ingredients deep into the skin's dermis. The micro-stimulation of the dermis by the needles activates skin cells, supporting the production of elasticity-enhancing components like collagen and elastin. This approach can gradually improve even challenging skin damage, such as enlarged pores and crater-like acne scars, leading to a plump, revitalized complexion.

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RESERVATION
24-hour reception
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Treatment area

TREATMENT AREA

Face and hands

Treatment Process

CONTENT OF TREATMENT

Physician's examination and counseling

We listen to your concerns and propose a treatment plan tailored to your needs. While local anesthesia is included in the procedure, nitrous oxide anesthesia is also available at an additional cost. If you are concerned about pain, please consult with us.

医師の診察・カウンセリング

Makeup Removal / Anesthesia

Before the procedure, cleansing and washing are completed, and local anesthesia is administered to the treatment area.

メイクオフ・麻酔

treatment

Once the anesthesia takes effect, we will inject the filler. The procedure time varies depending on the treatment area and scope, but it typically takes about 30 minutes to complete.

施術

Schedule of Charges

PRICE LIST
GOURI Price List

GOURI

Treatment Details one bottle 2 bottles 3 bottles
GOURI ¥110,000 ¥209,000 ¥297,000

Other

Treatment Details Standard rate
Treatment fee ¥24,200
Needle fee per site ¥2,420
Option: Exosome 1V ¥55,000
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CONCEPT
CONCEPT
Beyond the boundaries of aesthetic medicine,
Lifestyle Beautyis
proposed.

Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.

Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.

Recommended products for this concern

RECOMMENDED PRODUCTS

Frequently Asked Questions About GOURI

Q&A

Is there any downtime?

As downtime for Gouri, redness, swelling, edema, bruising, hives, and itching may occur. These symptoms typically subside over time and become unnoticeable within a few hours to two days for most people. Additionally, side effects such as bruising, allergic reactions, and post-treatment skin swelling may occur. If you wish to undergo skin treatment after Gouri, please wait one month before receiving it.

How long does the effect last?

Individual results may vary, but Gouli is said to last for several months because it takes relatively longer to break down beneath the skin. After injection, the skin naturally builds volume and lifts over about one month, supporting the increase of your own collagen.

Should I get Gouri treatments regularly? If so, how often?

At Bianca, local anesthesia is standard for Gouli procedures and is included in the treatment fee. For those concerned about pain, we also offer nitrous oxide anesthesia as an option (¥6,050 per session). While rarely used for Gouli procedures, Bianca can also accommodate anesthetic cream (¥3,630 per area) or block anesthesia (¥19,800 per session). Please consult with us regarding these options as needed.

What's the difference between Gouri and Jubellock?

Gouri and Shuveluck are both skin-nurturing injections that stimulate fibroblasts using components employed in thread lifts to support collagen production. Gouri primarily contains PCL (polycaprolactone), while Shuveluck primarily contains PDLLA (poly-DL-lactic acid) and hyaluronic acid. The PCL in Gouri is liquid-based, allowing it to spread evenly and deliver a natural, youthful appearance. In contrast, the PDLLA in Shuveluck is particle-based, making it ideal for precise, pinpoint injections.

Are there any treatments that work well with Gouri?

From the perspective of aiding wound repair, Gouli and high-concentration vitamin C IV drips are a highly compatible treatment combination. Additionally, Gouli delivery using the Dermapen 4 facilitates the delivery of cosmetic ingredients deep into the skin, making it another excellent pairing.

What is a collagen booster?

Collagen boosters are a type of skin-enhancing injection designed to stimulate the dermal layer of the skin, supporting collagen production while also promoting soft tissue repair and influencing skin tissue. Representative ingredients include PCL (polycaprolactone), the main component of Gouri, and PLA (polylactic acid). These injections are popular among those seeking skin rejuvenation.

Is Gouli available to anyone?

We cannot perform treatments on individuals who may be pregnant, are breastfeeding, or are within three months postpartum. Additionally, individuals with bruising or undergoing treatment cannot receive treatment for one month after the procedure, as this may prolong the bruising.

【Treatment Details】Gouri
Recommended Treatment Period and Frequency: Three sessions every three months. Treatment may resume after one year following a medical examination. *May vary depending on individual condition.
【Risks and Side Effects】Redness, swelling, edema, bruising, hives, puffiness, itching, etc.
【Important Notes Regarding Unapproved Medicines】
・This treatment may involve the use of unapproved pharmaceuticals that have not received regulatory approval in Japan.
・Medicines used in treatments are imported through personal import procedures under the supervision of a physician. For details, please refer to the Ministry of Health, Labour and Welfare's "Information on Medicines Requiring Caution for Personal Import."
 https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there may be no other domestically approved pharmaceuticals containing the same ingredients.
・Information regarding safety and other matters in other countries
-"GOURI" has obtained approval for the European CE Mark.
・Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, you may not be eligible for the national pharmaceutical adverse reaction victim relief system.

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