Manjaro (GIP/GLP-1 receptor agonist)
MOUNJARO
Support weight loss with the spotlight GLP-1/GIP receptor agonist!
Control appetite with a weekly subcutaneous injection
- Helps suppress appetite to support weight loss
- The effect lasts with a weekly subcutaneous injection.
- No need to visit the hospital because you can self-administer injections at home
A sustained-release GIP/GLP-1 receptor agonist with potential for weight reduction
Aiming for healthy weight loss under the guidance of a physician
BIANCA CLINIC considers aesthetic internal medicine the pinnacle of cosmetic medicine and has established a dedicated department. We introduce world-class treatments to support health and beauty from within.
Mangaro (generic name: tirzepatide), available at BIANCA CLINIC, is a long-acting GIP/GLP-1 receptor agonist that can help reduce blood sugar levels and suppress appetite, thereby supporting weight loss. With the support of our aesthetic medicine specialists, you can work toward achieving a healthier body.
Schedule of Charges
PRICE LIST| Treatment Details | Prescription Quantity/Supplement | Standard rate |
|---|---|---|
| Mangarlo (GIP/GLP-1) | 2.5mg/2 bottles (2 weeks' supply) | ¥27,500 |
| Mangarlo (GIP/GLP-1) | 5mg/2 bottles (2 weeks' supply) | ¥38,500 |
| Mangarlo (GIP/GLP-1) | 7.5mg/2 bottles (2 weeks' supply) | ¥59,500 |
| Blood draw fee | First time only | 3,300 yen |
| Consultation fee | Only for the initial prescription | ¥12,100 |
※Includes disinfection and needle fees
※Blood tests are available Monday through Saturday only (not available on Sundays or holidays).
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSWhat is Manjaro?
Mangaro is the world's first long-acting GIP/GLP-1 receptor agonist approved by the Ministry of Health, Labour and Welfare in 2023 as a new treatment for type 2 diabetes. While GLP-1 receptor agonists have been available as diabetes treatments before, Mangaro also incorporates the action of the insulin-secreting polypeptide (GIP). Consequently, it is a medication expected to support blood glucose control, appetite suppression, and weight loss.
The effects of hormones contained in Manjaro
Mangaro's characteristic is that it acts on GIP receptors in addition to GLP-1 receptors. GLP-1 and GIP are intestinal hormones normally secreted in response to food intake; they act on the pancreas to promote insulin secretion and lower blood glucose levels.
It is said to be relatively safe with a low risk of hypoglycemia because it promotes insulin secretion only when blood glucose levels are high.
<The Functions of GLP-1 and GIP>
GLP-1 (Glucagon-like Peptide-1)... acts on the hypothalamus (satiety center) in the brain to suppress appetite
GIP (Glucose-dependent insulinotropic polypeptide)... Promotes the secretion of glucagon, which in addition to insulin, stimulates lipolysis and suppresses appetite.
The feeling of fullness after a meal is due to the secretion of GLP-1 and GIP. By injecting Manjaro, which combines the effects of both GIP and GLP-1, it is expected to act on the satiety center and suppress appetite.
A weekly self-injection is expected to be effective.
The usage is simple: inject the medication subcutaneously once a week using a pen-style injector. A single dose is delivered with just the push of a button, eliminating the need for dose adjustment or handling needles. Manjaro's action helps naturally reduce food intake without strict dietary restrictions, leading to weight loss.
Benefits
MERITYou can reduce your calorie intake without resorting to extreme dietary restrictions.
Mangosteen helps suppress appetite and regulate blood sugar levels, making it possible to reduce calorie intake without resorting to extreme dietary restrictions.
The effect lasts with just one injection per week.
Conventional GLP-1 receptor agonists primarily required once-daily or more frequent dosing, whereas Manjaro delivers sustained effects with just one weekly subcutaneous injection, making it a less burdensome option.
Since you can administer it yourself, the number of clinic visits is reduced.
Manjaro is an easy-to-use kit formulation. A key feature is that patients can administer it themselves, reducing the number of clinic visits required. Simply apply the opened kit and press to inject—it's hassle-free.
Recommended Features
RECOMMENDED POINTSYou can aim to lose weight through the effects of hormones.
The rejuvenation method scientifically proven to be most effective in research to date is calorie restriction. However, extreme dietary restrictions often lead to stress buildup or overeating as a rebound effect, making them difficult to sustain successfully.
Mangosteen is characterized by its ability to act on the satiety center to suppress appetite and inhibit gastric activity to enhance feelings of fullness. This action naturally curbs appetite, allowing one to feel satisfied with smaller meals, and can lead to healthy weight loss.
Advice on adopting weight-loss lifestyle habits following treatment with Manjaro
Manjaro may help with weight loss, but research shows that stopping the medication often leads to rebound weight gain. This means that even if calorie intake is reduced and weight is lost while taking it, there is a risk of returning to the original weight once the medication is discontinued. To maintain the weight loss effect, it is crucial to combine Manjaro use with adopting healthy eating habits and establishing an exercise routine—essentially creating a lifestyle conducive to weight maintenance.
At Bianca Clinic, we also offer treatments that comprehensively address health based on each patient's lifestyle and genetic background, including services like the Epigenetic Clock to assess biological age and orthomolecular nutritional therapy.
Manjaro is not suitable for everyone.
Mangaro is not prescribed to individuals who are underweight due to its potential weight loss effects and associated side effects. Mangaro can only be prescribed to individuals with a BMI of 23 or higher. Please note that it cannot be prescribed to individuals with a BMI of 23. BMI is calculated as weight (kg) divided by height (m) squared. Please measure your BMI before your appointment.
Treatment area
TREATMENT AREAabdomen or thigh
Treatment Process
CONTENT OF TREATMENTCounseling and Physician Consultation
First, we will listen to your concerns during a consultation, followed by an examination by a physician. After confirming your BMI, medical history, and any medications you are currently taking, we will explain the characteristics, side effects, and usage of the medication. You can then decide whether you wish to proceed with the prescription.
Blood draw (first time only)
A blood test is required only for the initial visit to assess your physical condition before treatment begins and to monitor your treatment progress.
Prescription
Based on the physician's examination and blood test results, if Manjaro can be prescribed, a nurse will instruct you on how to administer the injection and give the first dose. The standard procedure is to start with an initial dose of 2.5mg, continue for 4 weeks to monitor for side effects, and then switch to a maintenance dose of 5mg.
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
Treatment Details: Subcutaneous injection of a long-acting GIP/GLP-1 receptor agonist
Estimated treatment period and frequency: Weekly subcutaneous injections
Side effects and risks: Nausea, vomiting, loss of appetite, fatigue, etc.
Treatment Using Unapproved Medical Devices, Unapproved Pharmaceuticals, and Other Unapproved Products
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medications and medical devices used for treatment are introduced based on the judgment of our clinic's physicians.
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
Mangaro is a pharmaceutical product approved for the treatment of type 2 diabetes. Eli Lilly Japan has obtained manufacturing and marketing approval.
-This product is not approved in Japan for cosmetic purposes or for the treatment of obesity.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.
Frequently Asked Questions About Mangjaro (GIP/GLP-1 Receptor Agonist)
Q&AIs Manjaro dangerous?
The risk of hypoglycemia with Manjaro is considered relatively low. However, if excessive dietary restrictions are implemented alongside Manjaro use, symptoms such as dizziness, fatigue, and palpitations may occur as signs of hypoglycemia. If you experience any of these symptoms, consult your doctor immediately. Additionally, be sure to inform your doctor beforehand if you have a medical history or are taking other medications.
Does the Manjaro injection hurt?
The Manjaro needle is thin and short, so the pain is minimal. However, pain perception varies from person to person; some may feel no pain at all, while others may feel a slight discomfort.
Are there any side effects with Manjaro?
Mangaro suppresses gastrointestinal activity, which may reduce appetite but can also cause gastrointestinal symptoms such as loss of appetite or nausea. The severity and duration of side effects vary from person to person, but digestive symptoms tend to occur more frequently shortly after starting treatment. If you experience any concerning symptoms, please consult your doctor.
Should I stop using it if side effects appear?
Do not stop using the medication on your own; consult your doctor. These are generally temporary side effects that usually lessen as your body adjusts to the medication. However, if you experience severe symptoms, seek immediate medical attention.
Please tell me the differences between Manjaro and other GLP-1 receptor agonists.
The difference between Mangalor and other GLP-1 receptor agonists lies in the number of hormones they target. GLP-1 receptor agonists act only on GLP-1, while Mangalor acts on both GLP-1 and GIP. Therefore, Mangalor is expected to be more effective than conventional GLP-1 receptor agonists. Research also suggests it is less likely to cause side effects such as gastrointestinal symptoms.
Is there any way to purchase Manjaro outside of medical institutions?
Mangaro cannot be purchased outside of medical institutions. You can only purchase it after receiving a doctor's examination and being deemed suitable for the medication. Please avoid using personal imports from overseas or online retailers, as these offer no guarantee of quality despite being cheaper.
Who is not eligible for a Manjaro prescription?
Mangarlo has weight-loss effects and cannot be prescribed to individuals with a BMI of 22 or below. Additionally, if you are taking other diabetes medications besides Mangarlo, there is a risk of hypoglycemia. Always inform your doctor before taking it and avoid combining medications on your own. Furthermore, it may not be prescribed if you have severe gastrointestinal disorders, as it could potentially affect the digestive system. If you have any other medical history or are taking other medications, please inform your doctor during your consultation.
When will the effects of Manjaro start to appear?
The timing of when you notice the effects varies from person to person, but it's common to feel a decrease in appetite several weeks after starting treatment. Blood sugar levels also tend to improve within about one to two weeks.
When is the best time to take Manjaro?
Mangaro is a medication administered on the same day each week. If you miss a dose or forget to administer it, and there are 3 days (72 hours) or more until the next scheduled dose, administer it immediately and then administer the next dose on the scheduled day. If there are less than 3 days (72 hours) until the next scheduled dose, do not administer it immediately; instead, administer it on the next scheduled day.
Is Manjaro covered by insurance?
Mangaro is covered by insurance as a treatment for type 2 diabetes. For obesity, it is not covered by insurance and requires out-of-pocket payment.
Please explain the difference between Manjaro and insulin injections.
Other diabetes medications besides Manjaro include insulin injections. This method involves injecting artificially produced insulin to supplement insulin levels. Manjaro is a medication that works by stimulating insulin secretion and is different from insulin injections.
Please tell me how to store mangoes.
Manjaro is a peptide hormone, and its effectiveness may be compromised by high temperatures or direct sunlight, so extreme care must be taken with storage. It should generally be stored in a refrigerator, taking care to avoid freezing. If a refrigerator is unavailable, it can be stored at room temperature below 30°C for up to 21 days.