nanostem
NANOSTEM
Approach with autologous cells! Advanced treatment attracting worldwide attention
Next-generation anti-aging care that “regenerates” the skin from the root
- Born from the fusion of two technologies! BIANCA's exclusive advanced skin quality improvement treatment
- Targets complex skin concerns! Expect natural, smooth skin texture improvement.
- Using your own cells minimizes risk! Downtime is short, causing minimal disruption to daily life.
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Pioneering the introduction of nanostems in Japan!
Bianca's New Approach to Skin Regeneration
Bianca Clinic has been quick to adopt Nanostem, a treatment still rarely introduced in Japan! Applying insights from regenerative medicine, this procedure is ideal for those seeking anti-aging care that targets the very essence of skin quality.
NanoStem combines Silky Fat with Dermapen 4, focusing not on volume replacement like traditional fat injections, but solely on skin regeneration. This results in a natural finish and long-lasting effects. You'll experience the sensation of “cultivating” your skin's transformation.
For those seeking fundamental anti-aging care that addresses skin concerns arising with age at their root, this treatment is Bianca's “new option for skin regeneration.”
Case Presentation
CASES
Downtime
DOWNTIMEAfter the procedure, your skin may feel drier than usual. Please moisturize thoroughly and avoid sun exposure.
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CHARACTERISTICSWhat is Nanostem?
NanoStem is an anti-aging treatment that introduces Silky Fat—extracted from the patient's own fat and specially processed—into the skin using Dermapen 4. First, fat collected from the patient is centrifuged to remove waste components, refining it into Condensed Rich Fat (CRF). Bianca's unique strength lies in using Silky Fat, obtained by further micronizing and refining this CRF.
This Silky Fat is characterized by its even finer fat particle size compared to conventional nano-fat, which processes CRF fat into smaller particles. Rich in stem cells, exosomes, and growth factors, it supports the skin's inherent natural healing and regenerative abilities, aiming to improve skin quality.
By delivering this Silky Fat to the skin's very shallow layer using the Dermapen 4 micro-needling device with its ultra-fine needles, it stimulates skin regeneration at the cellular level.
Dermapen 4 uses 16 needles to create micro-channels in the skin, uniformly delivering medications and active ingredients while stimulating the body's natural wound-healing response. When combined with Silky Fat, it promotes deep skin reconstruction, helping restore firmness and elasticity often lost with age.
Bianca Clinic is at the forefront of introducing advanced aesthetic treatments that harness the skin's regenerative power. These treatments are chosen by those who prioritize a natural finish and those seeking to fundamentally address their skin concerns.
Ultra-fine needles penetrate the skin! Efficiently delivers CRF to the superficial dermis.
At NanoStem, we use the micro-needles of the Dermapen 4 to create microscopic channels in the skin. Through these channels, Silky Fat is delivered deep into the skin (the superficial dermis). Silky Fat is rich in CRF-derived stem cells, exosomes, and growth factors, which work to enhance the skin's repair and regenerative capabilities.
The needles used in the procedure are extremely fine, minimizing skin stress and offering a more natural finish compared to traditional fat injections—a significant advantage. It can be applied to the entire face, including the forehead, cheeks, and jawline, as well as delicate areas like the eye and mouth regions. Furthermore, the Dermapen itself stimulates the body's wound-healing response, supporting collagen production and promoting overall skin quality improvement.
Awaken skin's firmness and radiance from within! Natural, long-lasting beauty effects
Silky Fat contains adipose-derived stem cells, also known as stem cell fat injections, which are gaining attention as ingredients that support the skin's inherent regenerative power. Growth factors and cytokines secreted by these cells are suggested to activate fibroblasts, promoting the production of collagen and elastin. This approach is believed to gradually restore the skin's firmness and radiance.
The effects of NanoStem are typically felt over several weeks to months, with many users noticing changes in skin texture. This gradual transformation makes it less noticeable to others while delivering a natural rejuvenation experience. For those seeking a fundamental solution to age-related skin concerns, NanoStem offers a new approach to anti-aging care—a sensation of skin nurturing from within.
Benefits
MERITRegenerative power that fundamentally enhances skin firmness and elasticity
The stem cells contained in Silky Fat work to promote collagen and elastin production. This gently firms and plumps the skin from within, gradually restoring elasticity and radiance.
Addresses complex skin concerns such as enlarged pores, fine lines, acne scars, and dullness
By promoting skin reconstruction, it simultaneously addresses various skin concerns such as enlarged pores, fine lines, acne scars, and dullness.
Because it's derived from your own tissue, it enables minimally invasive treatment with less skin damage.
Since the patient's own fat is used, the risk of rejection is low and skin irritation is minimized. This procedure prioritizes safety and a natural finish.
Recommended Features
RECOMMENDED POINTSCan be applied to areas of concern beyond just the face, such as the neck and décolletage.
NanoStem is not only suitable for facial treatments but also addresses areas prone to showing signs of aging, such as the neck, décolleté, buttocks, and the backs of the hands. By adjusting the treatment areas and fat extraction volume according to individual concerns, it enables customized procedures aimed at improving skin quality throughout the entire body.
At Bianca, we offer personalized treatment plans tailored to each patient. If you have any areas of concern, please feel free to consult with us.
Experience the effects gradually! Long-term skin cultivation for natural back-aging
The effects of NanoStem typically do not appear within days of treatment; instead, they tend to emerge gradually over time. Over several months, collagen and elastin production increases, and the skin's texture gradually becomes smoother and more refined.
Results vary by individual, but the peak effect is typically seen after 3 to 6 months. This makes it appealing because others will naturally notice the change, asking, "Has your skin been looking better lately?" It's the ideal anti-aging care for those seeking to cultivate beauty over the long term, rather than focusing on short-term changes.
Combining with other treatments is also effective! For even more beautiful skin.
NanoStem can be combined with other cosmetic treatments to achieve synergistic skin beautifying effects. We particularly recommend pairing it with PRP therapy, laser treatments, and high-concentration vitamin C IV drips that support recovery.
By combining NanoStem, which promotes skin regeneration, with treatments that enhance blood circulation and provide antioxidant effects, we can deliver more comprehensive care—tightening skin, evening out tone, and boosting radiance. This combination therapy expands possibilities for customized treatments, ideal for those seeking simultaneous solutions to multiple concerns. If you're thinking, "I want to resolve all my concerns at once!", please feel free to consult with Bianca.
Treatment area
TREATMENT AREAFace, neck, décolletage, buttocks, back of the hands
Treatment Process
CONTENT OF TREATMENTPhysician's examination and counseling
We carefully assess your skin condition and concerns to determine if NanoStem is suitable. From a dermatological perspective, we meticulously plan the treatment area, delivery depth, and fat harvesting site.
Liposuction
The necessary amount of fat is harvested from areas such as the abdomen and thighs. Anesthesia can be chosen between intravenous sedation or relaxation anesthesia. Liposuction is performed while you are asleep, minimizing discomfort and anxiety during the procedure. While employing surgical techniques, we prioritize patient comfort and safety, ensuring the burden is kept to a minimum.
treatment
The harvested fat is processed into Silky Fat, rich in stem cells and growth factors. Using Dermapen 4, it is uniformly introduced into the superficial dermis layer of the skin. This approach leverages the regenerative power of stem cells to promote the skin's own reconstruction.
NanoStem is Bianca's unique comprehensive treatment process that integrates three fields: dermatology, surgery, and regenerative medicine. Leveraging expertise from each field, NanoStem represents the next step in anti-aging care that our clinic proudly offers.
Schedule of Charges
PRICE LISTnanostem
| Medications/Items | Body Part / Plan | Amount |
|---|---|---|
| Fat Extraction Processing Fee | — | ¥242,000 |
| nanostem | Face, Neck, Décolletage, Back of Hands (each) | ¥110,000 |
| nanostem | buttocks | ¥220,000 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
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Frequently Asked Questions About Nanostem
Q&AWhat is Nanostem? What effects does it have?
NanoStem is a treatment that uses the Dermapen 4 to introduce Silky Fat, which is processed from the patient's own fat. It works to stimulate the skin's regenerative power, aiming for comprehensive care that addresses firmness, radiance, fine lines, enlarged pores, and acne scars. As skin texture gradually improves over time, it is well-suited for those seeking a natural rejuvenation.
Does NanoStem work for dark circles and hollows under the eyes?
The skin around the eyes is thin and delicate, but the Silky Fat used in NanoStem is exceptionally fine and smooth. It consists of fat particles finer than those in conventional Nano Fat. Therefore, it is also utilized as an approach for fat injection targeting dark circles and hollows under the eyes. It blends naturally with the skin around the eyes, aiming to improve texture and color tone.
How long do the effects of NanoStem last?
The effects of NanoStem typically manifest gradually over several months rather than immediately after treatment. The peak effect occurs approximately 3 to 6 months post-treatment, with skin texture improving steadily. While individual results vary, the effects generally last for about six months to a year, making it suitable for those seeking to cultivate naturally beautiful skin over the long term.
Is the Nanostem treatment painful?
Typically, numbing cream is used for Dermapen treatments, but NanoStem allows you to choose intravenous sedation or relaxation anesthesia, enabling you to undergo the procedure while asleep. Even those concerned about the pain of Dermapen 4 can receive treatment with peace of mind. After the procedure, temporary redness or stinging may occur, but in most cases, these subside naturally within a few days.
What is the difference between nanostem and fat injection (Micro CRF or Condensed Rich)?
NanoStem is intended for cell regeneration, while fat grafting (such as CRF) primarily aims to create volume. Both utilize the patient's own fat, but their application varies depending on the purpose and injection site.
What are the downtime, side effects, and risks associated with NanoStem?
The downtime for NanoStem, which combines Silky Fat and Dermapen 4, is relatively short, with post-treatment redness and dryness lasting about 3 to 5 days. Since it uses the patient's own tissue, side effects and risks are relatively low, making it a treatment designed with safety in mind.
Does combining it with fat grafting increase the survival rate?
Improved fat graft survival rates are expected with optimized regeneration environments. Silky Fat, in particular, is rich in cytokines and is considered to readily produce synergistic effects. This procedure is also well-suited for addressing concerns such as "fat grafts not taking."
Can Nanostem be used in combination with other treatments?
NanoStem is a regenerative approach that offers synergistic benefits when combined with other cosmetic treatments. At Bianca Clinic, we particularly recommend pairing it with PRP therapy, laser treatments, and high-concentration vitamin C IV drips. For those with multiple concerns, we propose customized treatment plans tailored to your specific goals.
Can Nanostem fail?
Due to the nature of the treatment, significant risks are minimal, but individual differences may affect how noticeable the effects are. Proper diagnosis by a physician is essential. If you have any concerns, please feel free to discuss them during your consultation.
How often should I receive Nanostem treatments?
Nano Stem is a treatment where you can experience significant results even after just one session. For those aiming for longer-lasting beautiful skin, some clients continue with regular treatments about once a year. The optimal frequency varies depending on your skin condition, so we will recommend it during your consultation.
Are there any recommended aftercare steps following a NanoStem treatment?
After NanoStem treatment, the skin becomes delicate. Incorporating skincare products containing tranexamic acid and EGF (epidermal growth factor) can support regeneration and help prevent pigmentation. Your physician will guide you on appropriate skincare, including home care, as needed.
Is it possible to undergo the procedure even with a lean body type?
Silky Fat can be processed even from small amounts of fat, but procedures may be difficult for extremely thin individuals. This will be confirmed during the preliminary consultation.
Are there people who are not suited for the treatment?
We may refrain from performing the procedure for individuals who are pregnant or breastfeeding, those prone to keloids, individuals with pacemakers, or those who are extremely thin and for whom fat extraction is difficult. We will advise you based on the physician's judgment.
【Treatment Details】Silky fat harvested from the abdomen or thighs is introduced into the skin using a Dermapen.
【Treatment Duration and Number of Sessions】1 session ※May vary depending on the condition.
【Risks and Side Effects】Swelling, bruising, pain, redness, dryness, stinging, hardening, unevenness, allergic reactions, etc.
【Important Notes Regarding Unapproved Devices and Pharmaceuticals】
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medications and medical devices used for treatment are introduced based on the judgment of our clinic's physicians.
・Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.
RESERVATION