NMN点滴療法・NAD+点滴療法

NMN infusion therapy and NAD+ infusion therapy

NMN・NAD+ Infusion Therapy

Reverse aging at the genetic level! For maintaining health, recovering from fatigue, and boosting cognitive function.

  • NMN is expected to reverse aging.
  • Improvements in physical and cognitive functions can be expected.
  • It also addresses skin concerns like wrinkles and sagging.
前田 陽子
Supervising Physician
Supervising physician in cosmetic medicine Yoko Maeda

To maximize your beauty, care for both the inside and outside is essential. We aim to bring advanced anti-aging treatments, such as peptide therapy common overseas, to our Japanese patients. While aesthetic medical approaches may offer more gradual results, they are crucial for building the foundation that supports beauty and youth. We combine nutritional therapy and lifestyle improvements with hormone replacement, peptide therapy, and regenerative medicine to propose personalized treatment plans. We provide long-term support for health and beauty from within.

Unique Initiatives at BIANCA CLINIC

Comprehensive Anti-Aging (Rejuvenation Medicine)
Providing customized treatment

In January 2022, the WHO (World Health Organization) added "age-related diseases" as a new category to the International Classification of Diseases*. This signaled to the world that the WHO is increasingly viewing aging as a disease—one that should be treated. Consequently, the traditional perception of aging as an inevitable, universal process is shifting. In recent years, the idea that rejuvenation is possible through appropriate treatment is becoming the global standard.

Bianca Clinic employs physicians with deep expertise in comprehensive anti-aging medicine (rejuvenation therapy), including NMN IV therapy and NAD+ IV therapy. Our team includes a board member of the Japanese Society of Aesthetic Internal Medicine and physicians licensed by the American Academy of Anti-Aging Medicine (A4M). We provide customized treatments tailored to each patient's needs from a wide range of options, based on an approach grounded in world-class anti-aging medicine. If you seek lasting youthfulness and beauty by caring for your body from the inside out, please consult with us.

*International Classification of Diseases... A list of causes of death and diseases published by the WHO

Schedule of Charges

PRICE LIST
NMN IV Therapy / NAD+ IV Therapy Price List

NAD IV Drip

Treatment Details 1 time 4 times 8 times
NAD IV Drip ¥60,500 ¥229,900 ¥435,600

NMN IV Drip

Treatment Details 1 time 4 times 8 times
NMN IV Drip ¥60,500 ¥229,900 ¥435,600
Option: Hydrogen Addition ¥11,880
WEB Reservation
RESERVATION
24-hour reception
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Downtime

DOWNTIME
Anesthesia
None
Pain
There is pain when inserting the IV needle.
IV drip time
NMN IV infusion takes approximately 15 to 30 minutes, while NAD+ IV infusion takes approximately 60 minutes.

Recommended for people like this

RECOMMENDED FOR:
feel stressed
I feel extremely fatigued and lethargic.
I can't concentrate for long.
I want to improve my sleep quality and overcome insomnia.
I want to take care of aging from the inside out.
*Age-appropriate care
I want to prevent aging
WEB Reservation
RESERVATION
24-hour reception
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Features

CHARACTERISTICS

NMN IV Therapy / NAD+ IV Therapy

NMN IV therapy is a next-generation anti-aging treatment gaining global attention, with research from Harvard Medical School and Keio University discovering its rejuvenating effects. For those seeking not just visible anti-aging care, but also a desire to maintain a youthful, healthy lifestyle indefinitely, boost stamina and concentration to work efficiently and vigorously, NMN IV therapy is ideal. It revitalizes vitality from within, helping you regain an ageless charm.

 

As we age, our physical functions such as skin and stamina decline. NMN intravenous therapy targets the cells that accelerate aging and can reverse the aging process, hence it is also called “back-aging therapy.” By activating genes deeply involved in aging, it supports reclaiming youthfulness and living healthily.

NMN点滴療法・NAD+点滴療法とは

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is an essential substance for energy production and cellular repair. NAD+ acts as a coenzyme that aids cellular chemical reactions, playing a role in converting nutrients from food into energy. It is also involved in processes that maintain cellular health and function; a decrease in NAD+ can contribute to aging and disease progression. One reason why aging-related issues like decreased stamina and slowed metabolism appear is linked to the age-related decline in NAD+. By age 60, the body's NAD+ levels are said to drop to about half of what they were at age 30.

 

NAD+ therapy, which supplements NAD+ externally, is gaining attention as a next-generation anti-aging treatment that aims to restore damage caused by aging and stress, promoting “rejuvenation from within.”

NAD+ therapy is believed to boost energy metabolism and enhance physical stamina and concentration by increasing NAD+ levels in the body. It is also said to have beneficial effects on anti-aging and beauty. This treatment is recommended for those who wish to "stay youthful and healthy for as long as possible" or "maintain focus for work or studies."

NAD+とは

What is NMN?

NMN (nicotinamide mononucleotide) is a vitamin-like substance naturally produced in the body and is a precursor to NAD+. When NMN enters the body, it undergoes several enzymatic reactions to convert into NAD+.

 

Incidentally, foods rich in NMN include edamame, broccoli, and cucumbers. For broccoli, consuming 100mg of NMN per day would require approximately 40kg (about 2000 florets).

NMNとは

Both aim to efficiently increase NAD+.

Both NMN IV therapy and NAD+ IV therapy aim to efficiently increase NAD+ levels. The difference between NMN IV therapy and NAD+ IV therapy lies in whether NAD+ is administered directly or its precursor is administered.

 

Due to its large molecular weight, NAD+ is difficult for cells to absorb directly, so it has been common practice to replenish it via intravenous infusion using NMN, which has a smaller molecular weight. NMN infusion therapy works gradually because it must undergo the conversion process to NAD+. However, as research advanced and a route for direct uptake of the larger NAD+ molecule was confirmed, NAD+ infusion therapy emerged. Since NAD+ is administered directly, there is no conversion process involved, and effects tend to be felt more quickly.

Benefits

MERIT

Can activate longevity genes

The human body contains sirtuin genes (longevity genes) believed to be involved in aging and health maintenance. NMN IV therapy and NAD+ IV therapy support cellular energy production and condition maintenance by supplementing NAD+, which is closely related to these sirtuin genes, within the body.
We aim to provide care from within to address the fatigue and discomfort that become more noticeable with age.

Rejuvenate physical and cognitive functions

NMN IV therapy and NAD+ IV therapy are characterized by their broad approach to overall physical condition, including stamina, metabolism, skin health, and sleep quality. Additionally, some individuals report changes in cognitive function, such as feeling "clear-headed" or experiencing "improved concentration."
It is selected as a treatment aimed at improving quality of life (QOL) while acknowledging age-related changes.

Since the ingredients are not broken down, it has a higher absorption rate compared to supplements.

While supplements are one way to take NMN, oral intake passes through the digestive system, meaning not all nutrients are absorbed. In contrast, intravenous administration allows components to bypass breakdown, resulting in high absorption rates within the body. Intravenous therapy enables efficient increases in NAD+ levels within the body.

Recommended Features

RECOMMENDED POINTS

For those experiencing severe fatigue or lethargy, intravenous drips offer efficient intake.

While taking NMN as a supplement is a recommended method, intravenous therapy is more suitable for those experiencing accumulated fatigue or severe lethargy. This is because intravenous administration allows NMN and NAD+ to be absorbed into the body more efficiently than oral intake, which must pass through the digestive system.

 

If you've previously struggled to see results from NMN-rich foods or supplements, we encourage you to consult with our clinic. We can advise on the appropriate NMN dosage for each patient based on age and constitution, and depending on your concerns, we may also recommend intravenous therapy.

Combination therapy with peptides to enhance NMN's effects may also be proposed.

Some patients who have taken NMN supplements or undergone NMN intravenous therapy report difficulty perceiving its effects. Recent research indicates that even when ingesting the same amount of NMN, some individuals experience increased NAD+ levels while others do not. The reason is that those who do not see increased NAD+ levels have higher expression of NAD+ degrading enzymes.

 

Peptide drugs that suppress NAD+ breakdown are gaining attention. Peptides are molecules composed of short chains of amino acids, naturally produced within the body. Consequently, peptide drugs have fewer side effects and have recently been applied in comprehensive anti-aging medicine, particularly in Europe and the United States.

 

Bianca Clinic employs physicians who have dedicated themselves to mastering world-class peptide therapy. If you've found it difficult to experience noticeable effects even after increasing NMN levels through supplements or IV drips, please feel free to consult with us.

Anti-aging care through treatments other than NMN IV therapy and NAD+ IV therapy

At BIANCA CLINIC, we offer numerous treatments for aging care from within the body, in addition to NMN IV therapy and NAD+ IV therapy. The causes of fatigue differ for each patient. For those seeking to address the root cause, we perform various tests and propose treatments such as orthomolecular nutritional therapy or hormone replacement therapy. On the other hand, for those without time for testing, we believe high-concentration vitamin C IV therapy or taking melatonin, a hormone that improves sleep, can also be effective against fatigue. In addition to our fatigue recovery menu, we also provide advice on sleep and relaxation techniques.

WEB Reservation
RESERVATION
24-hour reception
Click here for web reservation

Treatment area

TREATMENT AREA

Treatment Process

CONTENT OF TREATMENT

Counseling and Examination

Before administering NMN IV therapy or NAD+ IV therapy, our physician will explain the treatment details, risks, and potential effects. We will discuss your concerns and preferences during a consultation. Treatment will proceed only after mutual agreement between you and the physician.

カウンセリング・診察

Treatment (IV drip)

An NMN-containing formulation or an NAD+-containing formulation will be administered intravenously into either arm. The infusion takes approximately one hour.
※While some effects may be observed after a single treatment, for purposes such as maintaining health, preventing aging, or recovering from fatigue, we recommend continuing treatment once every 1 to 4 weeks.

治療(点滴)

End

After treatment, we ask that you rest for a while and stay well hydrated. Once the IV drip is finished, you may go home immediately.

終了
WEB Reservation
RESERVATION
24-hour reception
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CONCEPT
CONCEPT
Beyond the boundaries of aesthetic medicine,
Lifestyle Beautyis
proposed.

Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.

Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.

Recommended products for this concern

RECOMMENDED PRODUCTS

Frequently Asked Questions About NMN IV Therapy and NAD+ IV Therapy

Q&A

How much NMN and NAD+ is contained in one IV drip?

The dosage will be adjusted in consultation with your physician based on your symptoms and other factors.

Can NMN IV therapy and NAD+ IV therapy be administered during pregnancy or while breastfeeding?

Pregnant or breastfeeding individuals are advised to refrain from NMN IV therapy and NAD+ IV therapy. Please consult your physician for details.

What are the contraindications for NMN IV therapy and NAD+ IV therapy?

Pregnant or breastfeeding individuals, as well as those undergoing treatment for malignant tumors, cannot receive NMN IV therapy or NAD+ IV therapy. Additionally, depending on medications you are taking or your physical condition, you may be advised to refrain from treatment. Please consult your physician for details.

Is there a reason for getting an IV?

NMN can be consumed through food or supplements, but when taken orally, NMN absorbed from the intestines is transported throughout the body via the liver. In contrast, when administered intravenously, it is delivered directly from the bloodstream to various organs. Therefore, when consuming the same dosage, intravenous administration is said to yield more noticeable effects than oral intake.

How often should NMN IV therapy and NAD+ IV therapy be administered?

For those seeking to maintain health, prevent aging, or recover from fatigue, we recommend continuing treatment once every 1 to 4 weeks.

Can you feel the effects of NMN IV therapy or NAD+ IV therapy even after just one session?

While some effects can be observed even after a single treatment, we recommend continuing treatment on an ongoing basis for those seeking to maintain health, prevent aging, or recover from fatigue.

Is intravenous therapy/NAD+ intravenous therapy covered by insurance?

Please be advised that ANMN intravenous therapy is not covered by insurance. This is a self-pay treatment.

Can I undergo treatment while taking NMN supplements?

Individuals taking NMN supplements may also receive NMN IV therapy or NAD+ IV therapy. Please consult your physician regarding the frequency of NMN IV therapy or NAD+ IV therapy and any precautions.

NMN Intravenous Therapy
Treatment Details: Intravenous infusion of nicotinamide mononucleotide preparation
Recommended treatment frequency: Once every 1 to 4 weeks
Side Effects/Risks: Pain when the IV needle is inserted, mild vascular pain, etc.
Treatment Using Unapproved Medical Devices, Unapproved Pharmaceuticals, and Other Unapproved Products
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medicines and medical devices used for treatment are imported through personal import procedures under the judgment of our clinic's physicians. For information on medicines and other items requiring caution in personal import, please refer to the following.
 https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
No serious adverse effects have been reported.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.

peptide therapy
Treatment Details: Peptide Therapy
Estimated treatment duration and number of sessions: This varies depending on individual progress, but it typically takes 3 to 6 months to see results.
Side Effects and Risks:
・BPC-157: Hot flashes, dizziness, fatigue, headache, peripheral edema, etc.
・5-Amino-1MQ: Headache, nausea, difficulty falling asleep, etc.
・LGD-4033: Headache, dry mouth, acne, joint discomfort, hair loss, and at high doses, suppression of follicle-stimulating hormone and free testosterone.
・Semax: Associated with allergic symptoms, hair loss, mood changes, increased heart rate, etc.
・PT-141: Nausea, vomiting, facial flushing, headache, etc. At high doses, priapism, anorgasmia, etc.
Treatment Using Unapproved Medical Devices, Unapproved Pharmaceuticals, and Other Unapproved Products
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medicines and medical devices used for treatment are imported through personal import procedures under the judgment of our clinic's physicians. For information on medicines and other items requiring caution in personal import, please refer to the following.
 https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
No serious adverse effects have been reported for the medications used at our hospital.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.

WEB Reservation
RESERVATION
24-hour reception
Click here for web reservation
アイコン RESERVATION