Purified concentrated stem cell culture supernatant infusion
STEM THERAPYFor fatigue and signs of aging. Regenerative medicine for beauty and health.
- Addressing aging signs like dark spots and loss of firmness with IV therapy
- Revitalize your cells from within with a concentrated IV drip of domestically sourced stem cell-derived ingredients
- Achieve total body care from beauty to health management
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Customizable IV Drip Menu for Your Concerns Extensive Regenerative Therapy Options Available
“Aging is increasingly viewed as a treatable condition, and interest in regenerative medicine is growing within the aesthetic medical field. BIANCA CLINIC offers a wide range of regenerative medicine treatments, including PRP injections using high-concentration autologous platelet-rich plasma and intravenous or local injections of exosomes to promote tissue repair. Staffed by physicians specializing in anti-aging (rejuvenation) medicine, BIANCA CLINIC carefully assesses each patient's individual condition to deliver ideal, age-appropriate aging care.
Additionally, we offer intravenous therapies that work from the inside out, such as high-concentration vitamin C IV therapy (high-concentration vitamin IV therapy), NMN IV therapy, NAD+ IV therapy, and BIANCA DRIP (hydrogen therapy). Whether you have a specific treatment in mind or are unsure which therapy best suits your concerns, our physicians will recommend the most appropriate treatment through consultation. Please feel free to contact BIANCA Clinic for a consultation.
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSPurified and Concentrated Stem Cell Culture Supernatant Infusion
Purified and Concentrated Cell Culture Supernatant Infusion is a regenerative medicine therapy involving the purification and concentration of supernatant obtained from culturing human stem cells, which is then administered into the body. It targets aging or damaged cells, with the expectation of enhancing natural recovery capabilities.
Purified and concentrated cell culture supernatant is a formulation containing fewer harmful substances and richer growth factors than conventional stem cell culture media. The formulation used at our clinic is purified using only human-derived components, with no animal-derived ingredients used in the manufacturing process. It is purified and concentrated with careful attention to quality and safety, removing impurities such as ammonia released by cells as much as possible while retaining a high concentration of growth factors.
Treatment to regenerate aged cells and damaged tissue
Purified and concentrated cell culture supernatant is the supernatant obtained during the stem cell culture process. This supernatant is rich in various humoral factors, including growth factors, immune modulators, anti-inflammatory factors, and neurotrophic factors. These factors are believed to stimulate the activity of cells weakened by aging or damage, aiding in tissue repair and regeneration. Therefore, purified and concentrated cell culture supernatant infusion is a regenerative medicine treatment that enhances cellular regenerative capacity and holds promise for beauty and health maintenance.
【What Are Stem Cells?】
Stem cells are specialized cells possessing the ability to differentiate into cells that form various tissues such as skin, blood vessels, and bone (pluripotency), and are involved in tissue regeneration and repair. Stem cells are classified based on their origin and capabilities into embryonic stem cells (ES cells), adult stem cells, and iPS cells (induced pluripotent stem cells). It is said that stem cells decrease with age, potentially contributing to changes such as wrinkles and sagging.
Purified and Concentrated Stem Cell Culture Supernatant: Primary Growth Factors

Cytokines are components found in approximately 800 varieties within the body, performing various functions such as promoting skin and muscle cell proliferation, stimulating hair growth, and suppressing inflammation. Among these cytokines, growth factors are crucial components with high potential efficacy in the fields of beauty and regenerative medicine. Particularly noteworthy is HGF*, a growth factor within stem cell culture supernatant known to promote angiogenesis and tissue repair. At Bianca Clinic, we carefully select formulations with high HGF content and offer them as purified and concentrated stem cell culture supernatant intravenous drips.

*HGF…Abbreviation for hepatocyte growth factor
【Key Growth Factors】
aFGF: Stimulates fibroblasts, with expected effects on wound healing, wrinkle improvement, and skin brightening.
EGF: Promotes skin turnover and improves dark spots and dullness
IGF-1: Helps regenerate skin cells and enhances firmness and elasticity.
HGF: Promotes angiogenesis and tissue repair
TGF-β: Suppresses inflammation and improves sensitive skin conditions
PDGF: Stimulates cells responsible for tissue repair and promotes cell division
VEGF: Supports angiogenesis
KFG: Stimulates hair matrix cells to promote hair growth and regrowth
bFGF: Activates cells in blood vessels, muscles, and skin, and is also involved in nerve and bone regeneration.
※This does not guarantee the effectiveness of our purified and concentrated stem cell culture supernatant intravenous drip.
Benefits
MERITAchieve beautiful skin with fewer problems
By promoting collagen production and suppressing inflammation, it addresses dullness and loss of firmness caused by aging, leading to skin less prone to roughness.
Achieve comprehensive anti-aging care for your entire body through IV therapy.
By supplementing growth factors, this care focuses on repairing and regenerating aged cells and damaged tissues. It works from within to address signs of aging.
Supports health by promoting fatigue recovery and boosting immunity
Supports energy metabolism and helps maintain daily well-being. This aids in reducing fatigue and managing physical condition, supporting a healthy daily life.
Recommended Features
RECOMMENDED POINTSDomestically produced IV solutions for a youthful and healthy body
Some individuals may have concerns about the safety of formulations administered directly into the body via IV therapy. Bianca Clinic's purified and concentrated stem cell culture supernatant IV therapy utilizes a purified and concentrated stem cell culture supernatant derived exclusively from Japanese female donors. No animal-derived components are used in the manufacturing process. Furthermore, as this IV formulation is produced domestically, it is suitable for those who are particular about ingredients.
Not limited to purified and concentrated stem cell culture supernatant drips, Bianca Clinic carefully selects only the formulations our physicians would personally choose to use. Through regenerative medicine—available only at Bianca Clinic, where we are dedicated to health and beauty—we address age-related concerns and help you achieve a healthier, more positive daily life.
Other regenerative medicine therapies besides purified and concentrated stem cell culture supernatant drips
Our concentrated stem cell culture supernatant infusion provides holistic purification throughout the entire body, making it an ideal regenerative therapy for those seeking comprehensive health and skin management. Additionally, for individuals wishing to target specific concerns precisely, we also offer localized regenerative therapies.
For those concerned about enlarged pores, acne scars, or age-related wrinkles and sagging, the Exosome Facial is another option. The Exosome Facial is a treatment where micro-channels are created in the skin using a Dermapen, followed by the application of exosomes to promote skin regeneration. Furthermore, Bianca Clinic also offers the Vanier Facial, which utilizes high-concentration PRP (Platelet-Rich Plasma) derived from the patient's own blood.
Our physicians will propose regenerative medicine tailored to each patient based on their concerns and requests. We also offer cosmetic internal medicine consultations, so please feel free to inquire about your health or treatment options.
Treatment area
TREATMENT AREAAn IV will be administered into a vein in your arm.
Treatment Process
CONTENT OF TREATMENTCounseling and Examination
Before administering purified and concentrated stem cell culture supernatant intravenous drips, our physician will explain the treatment details, associated risks, and expected effects. During the consultation, we will also discuss your concerns and requests. The physician will then determine whether purified and concentrated stem cell culture supernatant intravenous drips are appropriate for you before proceeding with treatment.
Treatment (IV drip)
The purified concentrated stem cell culture supernatant will be administered via IV drip into either your left or right arm. The drip takes approximately 30 minutes. Please relax and enjoy your time. *While effects can be expected even after a single treatment, continuing treatment allows for a more comprehensive approach to health maintenance and anti-aging.
End
After treatment, please rest for a while. You may go home immediately after your IV drip is finished. On the day of treatment, be sure to stay well-hydrated and watch for any changes in your physical condition.
Schedule of Charges
PRICE LISTPurified concentrated stem cell culture supernatant infusion
| Number of times | Standard rate |
|---|---|
| 1 time | ¥60,280 |
| 5 times | ¥242,000 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
Frequently Asked Questions About Purified and Concentrated Stem Cell Culture Supernatant Infusions
Q&AWhat is purified and concentrated stem cell culture supernatant?
This product is derived from the supernatant obtained during stem cell culture, with impurities removed and beneficial components highly concentrated. Rich in growth factors, it holds promise for use in regenerative medicine. Bianca Clinic exclusively uses domestically produced formulations made from stem cells sourced from Japanese female donors.
What effects can be expected from purified and concentrated stem cell culture supernatant intravenous drips?
By suppressing inflammation and stimulating immune cells, it is expected to aid recovery from chronic fatigue, enhance skin regeneration, and support anti-aging care. It guides the body toward a youthful and healthy state from within.
For which concerns is the purified and concentrated stem cell culture supernatant drip recommended?
It can address concerns such as chronic fatigue, weakened immunity, loss of skin firmness and radiance, and signs of aging. It is also suitable for those seeking to restore their overall condition and regain the vitality of their younger years.
Can other treatments be administered simultaneously with purified and concentrated stem cell culture supernatant drips?
It is possible to receive other treatments while receiving an IV drip. Please consult your physician for details.
Is a single infusion of purified and concentrated stem cell culture supernatant effective?
Results may vary, but you can expect effects from the first infusion. However, for longer-lasting results, ongoing treatments are recommended.
How often should I receive purified and concentrated stem cell culture supernatant infusions?
The frequency varies depending on your goals and physical condition, but generally, a pace of once every 2 weeks to 1 month is recommended. Receiving treatments consistently makes it easier to experience the effects of immune regulation and anti-aging care. Please consult with your physician to plan an appropriate schedule.
What's the difference between purified concentrated stem cell culture supernatant IV drips and NMN IV drips? Which one is better?
NMN IV therapy supplements NMN (nicotinamide mononucleotide), a precursor to NAD+, which is involved in energy production and cellular repair. It is gaining attention as a “back-age therapy” that reverses aging. On the other hand, purified and concentrated stem cell culture supernatant IV therapy supplements various growth factors, supporting cellular regeneration and immune function. Neither purified and concentrated stem cell culture supernatant IV therapy nor NMN IV therapy is inherently superior; it is important to choose based on individual health conditions and goals.
Is the purified and concentrated stem cell culture supernatant infusion covered by insurance?
Purified and concentrated stem cell culture supernatant intravenous drips are not covered by insurance as they are self-pay treatments.
【Treatment Details】A therapy involving the direct intravenous administration of a purified and concentrated solution derived from the supernatant obtained during stem cell culture.
【Treatment Duration and Frequency Guidelines】Approximately once every 2 weeks to 1 month ※May vary depending on the condition.
【Risks and Side Effects】 Bruising, redness, etc., for about 1 to 2 weeks
【Important Notes Regarding Unapproved Devices and Pharmaceuticals】
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medications and medical devices used for treatment are imported through personal import procedures under the judgment of our clinic's physicians.
・For information on pharmaceuticals and other items requiring caution in personal imports, please refer to the following.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
-Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.