nouveau beer
NEAUVIA
Pursuing a natural finish with high elasticity and viscosity
New Hyaluronic Acid Formulation
- New hyaluronic acid formulation utilizing PEG crosslinker to minimize delayed-type allergic reactions
- Choose from 6 types to achieve volume enhancement and anti-aging care
- High heat resistance allows for combination treatments with RF high-frequency and HIFU on the same day.
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Newbia has been in clinical trials since 2012 and continues to this day.
No reports of delayed-type allergies
Has anyone experienced an allergic reaction after receiving hyaluronic acid injections? In fact, some individuals develop delayed-type allergies that occur some time after the injection.
Therefore, Bianca Clinic has introduced the new hyaluronic acid formulation, Newbia. Since the start of clinical trials in 2012 to the present*, there has been not a single report of delayed-type allergies. You can receive hyaluronic acid injections with peace of mind.
Additionally, our clinic has established the exclusive BIANCA METHOD, a unique injection technique performed by highly skilled physicians. This method achieves a beautiful, natural finish through meticulous design that considers the overall facial balance. A key strength of our clinic is that every physician provides high-level treatments based on the BIANCA METHOD. Please view each physician's case studies on the Bianca Clinic website and Instagram.
*As of February 2025
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSNew Beer
NEAUVIA is a type of hyaluronic acid formulation.
This product is characterized by its use of PEG (polyethylene glycol) crosslinking instead of BDDE (1,4-butanediol diglycidyl ether), a crosslinking agent (additive) commonly found in hyaluronic acid formulations.
The use of PEG achieves high elasticity, viscosity, and cohesiveness, enabling a more natural finish.
NEAUVIA's lineup is broadly divided into three categories.
・Volume Up: INTENSE LINE
・Volume Boost and Collagen Activation: STIMULATE LINE
・Anti-aging care and enhanced moisture retention: HYDRO DELUXE LINE
BIANCA CLINIC employs a total of six products: the four types of "INTENSE LINE," "STIMULATE," and the non-crosslinked hyaluronic acid formulation "HYDRO DELUXE." We provide PEG-crosslinked hyaluronic acid injections, distinct from conventional methods, using our proprietary [BIANCA METHOD].
What's the Difference Between the 4 INTENSE Lines?
The four products in the INTENSE line by Neuva available at our clinic are selected based on the specific area you wish to target. All products contain amino acids (glycine and L-proline).
【NEAUVIA INTENSE】
Hyaluronic acid concentration: 28 mg/ml
It is the hardest in the series and is also called a "shape-memory filler" due to its very high cohesiveness and viscosity.
Application Areas: Nose, Nasal Base, Chin, Facial Contour
【NEAUVIA INTENSE LV】
Hyaluronic acid concentration: 26 mg/mL
This is the hyaluronic acid most suitable for volume enhancement within the series.
Application areas: Forehead, temples, mid-face, nasolabial folds
【NEAUVIA INTENSE RHEOLOGY】
Hyaluronic acid concentration: 22 mg/mL
This hyaluronic acid offers just the right amount of volume and blends seamlessly into the skin.
Application area: Tear trough (the hollow beneath the inner part of the eye)
【NEAUVIA INTENSE FLUX】
Hyaluronic acid concentration: 26 mg/mL
This is the softest, smoothest, and most viscous hyaluronic acid in the series.
Application Areas: Fine lines, tear troughs
Features of STIMULATE
Our clinic offers not only the four INTENSE line products but also STIMULATE. STIMULATE is characterized by its 1% calcium hydroxyapatite (CaHA) formulation. In addition to its volume-enhancing effects, it also activates collagen production, helping to sculpt contours while promoting firm, resilient skin. The calcium particles are smaller than red blood cells and are metabolized within the body.
【NEAUVIA STIMULATE】
Hyaluronic acid concentration: 26 mg/mL
This formulation is expected to provide volume-enhancing effects and collagen-activating effects.
Application areas: Forehead, temples, midface, chin, etc.
Features of HYDRO DELUXE
HYDRO DELUXE is a formulation containing calcium hydroxyapatite (CaHA), non-crosslinked hyaluronic acid, and amino acids (glycine, L-proline). Unlike conventional hyaluronic acid products, it contains no additives to delay degradation or absorption within the body. This allows it to spread uniformly throughout the injection site, delivering a natural finish. It enhances skin hydration and improves skin texture. Suitable for use on areas prone to visible aging, such as the neck and hands, making it an ideal formulation for anti-aging care.
【NEAUVIA HYDRO DELUXE】
Non-crosslinked hyaluronic acid concentration: 18 mg/mL
This formulation enhances skin firmness and elasticity while boosting moisture retention, offering anti-aging benefits.
Areas of use: Face, neck, hands, etc.
Cross-linking used in hyaluronic acid formulations
Crosslinking agents used in hyaluronic acid formulations are additives employed to delay the breakdown and absorption of hyaluronic acid within the body. Crosslinking also affects the texture of hyaluronic acid; less crosslinking yields a softer texture, while more crosslinking results in a firmer texture. While crosslinking is crucial for sustaining the effects of hyaluronic acid, the conventional crosslinking agent BDDE has been suggested as a potential cause of complications following hyaluronic acid injections.
NEAUVIA is a novel hyaluronic acid formulation that uses PEG instead of BDDE as its cross-linking agent. PEG is a component used in the medical field, cosmetics, food, and other industries, with a history spanning over 160 years. The high elasticity, viscosity, and cohesiveness that characterize NEAUVIA are achieved through PEG cross-linking.
Benefits
MERITA more natural finish can be expected.
Thanks to its high elasticity, viscosity, and cohesiveness, hyaluronic acid delivers a natural finish.
Even if you are not compatible with BDDE crosslinking agents, you can still receive the treatment.
"INTENSE LINE" and "STIMULATE" are hyaluronic acid fillers that do not use the cross-linking agent BDDE, so they can be administered even to individuals who have previously experienced adverse reactions to BDDE.
Tailor your approach to facial concerns with six distinct treatments
Six types of hyaluronic acid formulations can be tailored to each facial area, enabling a customized approach to address your specific concerns.
Recommended Features
RECOMMENDED POINTSBenefits Provided by the Properties of PEG
Research has demonstrated that hyaluronic acid utilizing PEG cross-linking maintains consistent quality even when exposed to temperature fluctuations between -20°C and 75°C. Conversely, literature indicates that hyaluronic acid employing BDDE cross-linking exhibited a reduction of over 30% when subjected to heat at 40°C or 70°C for 30 to 60 seconds. This confirms that NEAUVIA hyaluronic acid possesses heat resistance.
Therefore, procedures such as RF radiofrequency, infrared, and HIFU can be performed on the same day as Newbia hyaluronic acid injection. Its resistance to temperature changes means the hyaluronic acid is less likely to break down after injection, allowing for longer-lasting effects. It is also less susceptible to temperature fluctuations during transport and storage, making it easier to maintain its quality.
【Less Likely to Cause Delayed-Type Allergies】Benefits of Low-Molecular-Weight PEG Crosslinking Combined with Two Types of Amino Acids
The low-molecular-weight PEG crosslinking used in Newbia is designed to minimize allergic reactions through patented manufacturing technology. Furthermore, its inclusion of two amino acids (glycine and L-proline) is expected to reduce post-injection swelling and the absorption of hyaluronic acid. Additionally, anti-inflammatory and free radical scavenging effects have been reported, with studies confirming an extremely low potential for post-treatment inflammation.
Newbia has sold over 7 million bottles since its launch in 2014, with no reports of delayed inflammatory reactions or granuloma formation. (As of December 2024)
Hyaluronic acid filler meeting the strict standards of the EU market
Newbia is the world's first hyaluronic acid formulation to obtain MDR (European Medical Device Regulation) approval and is currently sold in over 80 countries worldwide. IBSA, the manufacturer of Newbia, is a multinational corporation with production facilities and subsidiaries in Europe and the United States, and has recently exhibited at academic conferences in Japan.
The brand name Newbia means “new path.” As a hyaluronic acid utilizing a novel PEG cross-linking technology distinct from conventional methods, it is gaining significant attention within Japan as a contributor to global aesthetic medicine.
Newbia formulation used in BIANCA
NEAUVIA
INTENSE LINE
INTENSE is a series ideal for volume enhancement. Choose from four formulations with varying hyaluronic acid concentrations and viscosities to suit the specific area of application.
NEAUVIA INTENSE
NEAUVIA INTENSE LV
NEAUVIA INTENSE RHEOLOGY
NEAUVIA INTENSE FLUX
STIMULATE LINE
STIMULATE features a 1% concentration of calcium hydroxyapatite (CaHA). In addition to its volume-enhancing effects, it also activates collagen, helping to sculpt the skin while promoting firmness. The calcium particles are smaller than red blood cells and are metabolized within the body.
HYDRO DELUXE LINE
HYDRO DELUXE is a formulation containing calcium hydroxyapatite (CaHA), non-crosslinked hyaluronic acid, and amino acids (glycine, L-proline). Unlike conventional hyaluronic acid products, it contains no additives to delay degradation or absorption within the body. This allows it to spread uniformly throughout the injection site, delivering a natural finish. It enhances skin hydration and improves skin texture. Suitable for use on areas prone to visible aging, such as the neck and hands, making it an ideal formulation for anti-aging care.
Treatment area
TREATMENT AREAForehead, temples, tear troughs, tear troughs (the hollows under the eyes), nose, base of the nostrils, midface, nasolabial folds, chin, jawline, fine lines, etc.
Treatment Process
CONTENT OF TREATMENTPhysician's examination and counseling
We determine the injection sites and dosage for hyaluronic acid preparations. Since NEAUVIA uses different formulations depending on the area being treated, the specific product and dosage are decided during the consultation.
Makeup removal at the injection site
You may arrive at the clinic wearing makeup on the day of your treatment, but please remove any makeup from the injection sites before the procedure begins.
treatment
Hyaluronic acid is injected into your desired area. For those sensitive to pain, we can use anesthetic or needles designed to minimize discomfort.
Schedule of Charges
PRICE LISTNEAUVIA
| Product Name | Standard rate |
|---|---|
| NEAUVIA INTENSE | ¥165,000 |
| NEAUVIA INTENSE LV | ¥165,000 |
| NEAUVIA INTENSE RHEOLOGY | ¥165,000 |
| NEAUVIA INTENSE FLUX | ¥165,000 |
| NEAUVIA STIMULATE | ¥165,000 |
NEAUVIA HYDRO DELUXE
| Treatment Details | 1 time | 3 times |
|---|---|---|
| Full face | ¥77,000 | ¥220,000 |
| Part | ¥46,200 | ¥128,040 |
Other
| Treatment Details | Standard rate |
|---|---|
| Treatment fee | ¥24,200 |
| Needle fee per site | ¥2,420 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
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New Beer FAQ
Q&AHow long does the effect of NEAUVIA hyaluronic acid last after injection?
For NEAUVIA INTENSE, the duration of effect is 12 months. When used for nasolabial folds, studies have shown that the maximum effect is achieved one month after injection, rather than immediately after, and significant improvement is still observed even three months later.
How should I choose the type of hyaluronic acid in Newbia?
The four types of NEAUVIA hyaluronic acid products available at BIANCA CLINIC each differ in concentration and recommended application areas. During your consultation, our physician will discuss your concerns and determine which hyaluronic acid product is best suited for you.
Can Newbia's hyaluronic acid product be injected into the lips?
NEAUVIA offers hyaluronic acid for lips called "LIPS," but our clinic does not currently carry this product. Patients wishing to undergo hyaluronic acid lip injections at our clinic can receive treatment using hyaluronic acid products from other manufacturers.
Are there any disadvantages or risks associated with continuing to receive injections of Newbia or other hyaluronic acid products?
The effects of hyaluronic acid injections are not permanent, so regular treatments are necessary to maintain the results. Since hyaluronic acid is a naturally occurring component in the human body, continuing to receive hyaluronic acid injections is unlikely to cause health problems.
However, from an aesthetic perspective, repeatedly injecting only specific areas may disrupt the overall facial balance or result in unnatural expressions. When undergoing ongoing hyaluronic acid injections, it is crucial to use high-quality hyaluronic acid formulations and have injections administered by a physician with both technical skill and expertise, who carefully assesses facial balance during consultation.
After receiving a hyaluronic acid injection at New Beer, when can I apply makeup or take a shower?
After your NEAUVIA treatment, you may apply makeup and shower on the same day. However, please avoid applying makeup to the injection sites on the day of your treatment and wait until the following day. You may also wash your face and perform your skincare routine on the same day, but please be careful not to rub the injection sites.
After injecting Newbia hyaluronic acid solution, is it possible to experience swelling or redness?
After hyaluronic acid injections, bruising, swelling, and redness may occur for several days. If swelling or redness develops, it is advisable to cool the treated area using a cold pack or similar. Cooling the affected area causes blood vessels to constrict, which can help alleviate symptoms such as swelling and bruising.
When can I resume exercise after receiving Newbia hyaluronic acid injections?
On the day of your hyaluronic acid injection, please refrain from strenuous exercise. If your body becomes warm and blood flow increases after the injection, swelling, pain, or bruising may occur at the injection site. Therefore, please wait until the day after your procedure to engage in sweaty sports or use saunas.
Does Newbia's hyaluronic acid formulation dissolve with hyaluronidase?
Yes, it can be dissolved. Hyaluronidase is an enzyme naturally present in the human body that dissolves hyaluronic acid. If the results after hyaluronic acid injection differ from what you expected, hyaluronidase can dissolve the hyaluronic acid to restore your original shape.
If you wish to dissolve NEAUVIA hyaluronic acid, please understand that due to the nature of NEAUVIA, a greater amount of hyaluronidase will be required compared to dissolving conventional hyaluronic acid.
Treatment Details: Hyaluronic Acid Injection
Estimated treatment period and number of sessions: Approximately 9 to 12 months *Individual results may vary depending on the formulation used and the treatment area.
Side effects and risks: Redness, swelling, puffiness, pain, etc.
Treatment Using Unapproved Medical Devices, Unapproved Pharmaceuticals, and Other Unapproved Products
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
・Medicines and medical devices used for treatment are imported through personal import procedures under the judgment of our clinic's physicians. For information on medicines and other items requiring caution in personal import, please refer to the following.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
- Obtained CE marking under the MDR (European Medical Device Regulation)
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.
RESERVATION