harmonica
HARMONYCA™
Hybrid of hyaluronic acid and CaHA for volume enhancement and skin growth at the same time!
- Instant lift and volume boost in one bottle
- CaHA provides long-term support for collagen production
- Surface anesthesia + specialized needles for downtime management
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
BIANCA Original Technology “BIANCA METHODS” for a Natural Finish
The HarmonyCa™ procedure at Bianca Clinic is performed using the Bianca Method, our clinic's original technique.
The Bianca Method is a technique developed by Kazuyoshi Hotta, Chairman of Bianca, over more than a decade. It pursues a natural finish immediately after treatment using the minimum necessary injection volume. Consideration is given to minimizing pain to the utmost extent, including the composition of local anesthetics and the injection layer. To avoid risks associated with injection therapy, an injection method grounded in anatomy was explored.
Bianca Clinic leverages its extensive surgical expertise to deliver exceptional results in injectable treatments. Experience the natural finish achieved through the Bianca Method.
Case Presentation
CASES
Harmonica (HArmonyCa)
- Treatment Period and Number of Sessions
-
Left: Before treatment Right: 5 months after treatment
57 years old, 6 units used - Side Effects and Risks
-
Redness, swelling, edema, bruising, hives
Several hours to about two days
Harmonica (HArmonyCa)
- Treatment Period and Number of Sessions
-
Left: Before treatment Right: 5 months after treatment
57 years old, 6 units used - Side Effects and Risks
-
Redness, swelling, edema, bruising, hives
Several hours to about two days
Harmonica (HArmonyCa)
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: 4 months after treatment
- Side Effects and Risks
-
Redness, swelling, edema, bruising, hives
Several hours to about two days
Harmonica (HArmonyCa)
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: 4 months after treatment
- Side Effects and Risks
-
Redness, swelling, edema, bruising, hives
Several hours to about two days
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICS
Harmonica (HArmonyCa™) is
Harmonica is a hybrid injectable developed by France's Allergan Aesthetics, combining hyaluronic acid filler (HA) with calcium hydroxyapatite (CaHA). In addition to the volume-enhancing and lifting effects provided by hyaluronic acid, calcium hydroxyapatite gently supports collagen production. The combined action of these two components delivers immediate and long-lasting natural firmness and youthful skin texture.
Harmonica is suitable for contouring areas such as the forehead, temples, cheekbones, and jawline. Case studies have been presented at international conferences in Europe and America. At Bianca Clinic, we address discomfort and bruising during Harmonica procedures by using topical anesthesia, block anesthesia, and specialized needles. A key feature is the relatively short downtime, typically lasting a few hours to two days.
CaHA promotes collagen production over the long term
Calcium hydroxyapatite (CaHA) contained in Harmonica is a natural mineral also found in bones and teeth. When injected, CaHA targets skin lifting and contouring, delivering immediate volume-enhancing effects.
Not only does it provide immediate results, but the calcium microparticles remaining in the body also support collagen production over the long term. As the dermis thickens, you can expect improved skin texture. A key feature of CaHA is its long-lasting effect; depending on the area, results can be felt for 1 to 2 years after injection.
Surface anesthesia + specialized needles for downtime management
Many patients express anxiety about pain during injection treatments. At Bianca Clinic, most patients opt for injections after receiving local anesthesia. For those seeking stronger pain management, additional options such as nitrous oxide anesthesia or nerve block anesthesia are available.
The use of specialized needles minimizes downtime, with redness and swelling typically subsiding within two days. As the procedure is completed quickly, patients seeking an injectable treatment offering immediate and long-lasting results during their spare time are encouraged to consider this option.
Benefits
MERIT
Instant + Long-lasting: Lift immediately after injection & long-term firmness maintenance
The hybrid action of hyaluronic acid filler and calcium hydroxyapatite delivers both immediate and long-term effects.
Natural finish: Enhances skin texture for a radiant glow and sculpted look
Naturally enhance dimensionality with the Bianca Method. Improve skin texture and add radiance through skin-nurturing effects.
Local anesthesia + specialized needles minimize downtime and pain
Local anesthesia and specialized needles minimize pain concerns. Short procedure time ensures minimal downtime.
Recommended Features
RECOMMENDED POINTS
Achieve your desired look through highly accurate pre-treatment consultations
To achieve natural-looking results with harmonica, it is crucial to clearly define your desired outcome during the initial consultation and establish a thorough treatment plan. At Bianca Clinic, we analyze your facial features using the high-performance skin diagnostic device "VISIA®" and the 3D simulation system "VECTRA®". By simulating your post-treatment appearance, we bridge the gap between your expectations and the physician's vision.
【What VISIA® Can Tell You】
By capturing and analyzing color and UV photographs, we visualize potential spots and wrinkles beneath the skin's surface and quantify skin age. We can also analyze pores, skin texture, acne-prone skin, and skin tone.
【What VECTRA® Can Reveal】
We can create a 3D model of your face and simulate the final result from every angle. Since simulations can be performed down to the millimeter on your computer screen, you can compare the pre- and post-treatment facial images while deciding on your treatment plan.
Treatment plans tailored to life events
Harmonica is a formulation offering both immediate and long-term effects. While some individuals may feel the lifting effect from hyaluronic acid immediately after treatment, experiencing the skin-rejuvenating effects from CaHA requires some time following the procedure.
For special occasions like weddings, reunions, or photo shoots where you want your skin to look its best at a specific time, we recommend scheduling your treatment by counting back from the event date. Please discuss your desired injection areas and timing during your consultation. We will propose a plan to ensure the effects are visible when you need them most.
Combine with other treatments for even more ideal skin
You can combine other treatments with your harmonica session.
Before the Harmonica injection, you can combine any treatments from our skin care menu. It can also be combined with other injectable treatments like skin-enhancing injections or Botox on the same day. Since Harmonica is often injected from the forehead to the temples, combining it with Massage Peel and HydraFacial's Strobeskin is popular for those wanting extra radiance on the forehead.
If you have any treatments you'd like to try in combination with harmonica, please feel free to consult with us.
Treatment area
TREATMENT AREA
Forehead, temples, sunken cheeks, jawline
Treatment Process
CONTENT OF TREATMENT
Physician's examination and counseling
We will determine the injection sites and the injection volume.
Makeup removal at the injection site
If you arrive at the clinic wearing makeup, please remove it.
treatment
Harmonica is injected into the areas determined during the consultation. Depending on the amount, the injection itself takes approximately 30 to 60 minutes.
Schedule of Charges
PRICE LISTharmonica
| Product Name | Standard rate |
|---|---|
| harmonica | ¥110,000 |
Other
| Treatment Details | Standard rate |
|---|---|
| Treatment fee | ¥24,200 |
| Needle fee per site | ¥2,420 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
Harmonica FAQ
Q&AWhen will the effects of the harmonica kick in?
Immediately after injection, swelling or puffiness may occur due to the anesthetic or the procedure itself. However, some individuals notice changes such as lifting or volume enhancement right after the injection.
What is calcium hydroxyapatite?
Calcium hydroxyapatite is a component found in teeth and bones. In the medical field, it is used in a wide range of treatments, including orthopedics, dentistry, and otolaryngology.
Compared to hyaluronic acid, it has higher viscosity and is used for cosmetic purposes due to its ability to firmly shape the area when injected. It is absorbed by the body within about one to one and a half years after injection.
Since it is a component naturally present in the human body, the relatively low incidence of reported allergies is another advantage.
Is there any pain during harmonica treatment?
Many patients believe hyaluronic acid injections are painful, so at Bianca Clinic, we perform treatments using the Bianca Method with pain management in mind. During the procedure, we often administer local anesthesia before injection, and nitrous oxide anesthesia or nerve block anesthesia can also be added.
How long does the effect of the harmonica last?
Depending on the injection site, the effects are said to last for about one to two years after a single appropriate dose is administered, similar to the duration of hyaluronic acid injections.
The harmonica gradually breaks down within the body over time, so if you feel the effects diminishing, re-injection is possible.
Is there any downtime?
After treatment, redness, swelling, edema, bruising, hives, or puffiness may occur. In all cases, these symptoms will subside over time and typically disappear within a few hours to two days.
How long does a harmonica procedure take?
The procedure time for harmonica injection varies depending on the amount and area, but generally takes about 30 to 60 minutes. Please allow ample time for your visit, as consultation and facial cleansing are also required.
What's the difference between Harmonica and other skin-nourishing injections?
The main components and mechanisms of skin nurturing differ. Below is a comparison of expected effects between other skin nurturing injections available at Bianca Clinic.
【Harmonica】
Main Ingredients: Hyaluronic Acid Filler + Calcium Hydroxyapatite (CaHA)
Stimulates fibroblasts to address both volume enhancement and skin texture improvement
【Snekos】
Main Ingredients: Non-crosslinked hyaluronic acid + 6 amino acids
Simultaneously promotes collagen and elastin synthesis to address signs of aging
【Jubellook】
Main Ingredients: PDLLA (Poly-DL-Lactic Acid) and Non-Crosslinked Hyaluronic Acid
Targets pores, fine lines, redness, under-eye dark circles, and acne scars on the skin's surface
What's the difference between Harmonica and other hyaluronic acid injections?
The ingredients and expected effects differ.
【Harmonica】
A hybrid formulation of hyaluronic acid (HA) and calcium hydroxyapatite (CaHA). It offers both immediate volume enhancement from hyaluronic acid and long-term collagen production support from CaHA, promoting skin health. Ideal for sculpting facial contours across the entire face, including the forehead, temples, sunken cheeks, and jawline.
【Hyaluronic Acid Injection】
The main ingredient is hyaluronic acid (HA) only. It is suitable for enhancing the nose, reducing the appearance of nasolabial folds, and localized volume enhancement.
【Treatment Details】HArmonyCa™
【Estimated Treatment Period and Frequency】 Each session may be required at 1 to 2-year intervals. ※This varies depending on the individual's condition.
【Risks and Side Effects】Redness, swelling, edema, bruising, hives, puffiness, etc.
【Important Notes Regarding Unapproved Medicines】
・This treatment may involve the use of unapproved pharmaceuticals that have not received regulatory approval in Japan.
・Medicines used in treatments are imported through personal import procedures under the supervision of a physician. For details, please refer to the Ministry of Health, Labour and Welfare's "Information on Medicines Requiring Caution for Personal Import."
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there may be no other domestically approved pharmaceuticals containing the same ingredients.
・Serious risks or side effects may not yet be known.
・In the unlikely event of serious side effects, you may not be eligible for the national pharmaceutical adverse reaction victim relief system.
RESERVATION