Rejuran (Salmon injection)
REJURAN
Activates the skin's regenerative power!
Polynucleotide Injections Leading to a Youthful Impression
- Injection containing polynucleotides (PN) extracted from salmon DNA
- Activates the skin's regenerative power, enhancing firmness and elasticity for a youthful appearance.
- Effective for acne scars, wounds, fine lines around the delicate eye area, and dark circles
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Pain-Free Rejuran: Our Original Formula Designed for Comfort
At BIANCA CLINIC, we have independently researched and developed a unique formulation to minimize the stress caused by injection pain while maintaining the full efficacy of Rejuran. We offer "Pain-Free Rejuran," which combines anesthetics in a balanced blend. Furthermore, we use ultra-fine 34-gauge needles to reduce pain and bruising. To ensure precise delivery to the targeted layer, we strategically select between 4mm and 2mm needles depending on the treatment requirements.
We understand the feelings of fear and anxiety that come with treatments involving needles directly on the skin. We strive to provide pain-free procedures and take every measure to make the experience as comfortable as possible.
※The sensation of pain varies from person to person. Not all clients experience completely pain-free treatment.
Downtime
DOWNTIMERecommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSRejuran (Salmon Injection) is
Rejuran (Salmon Injection) is a skin booster containing polynucleotides (PN) extracted from salmon DNA, which promote the repair and regeneration of cells and tissues, as well as stimulate the formation of new blood vessels.
By stimulating fibroblasts to proliferate cells and regenerate skin, it adds thickness to the epidermis and dermis, improving skin firmness, tightening, and enhancing elasticity and volume. It also increases vascular endothelial growth factor (VEGF) to promote angiogenesis, offering localized blood flow improvement and helping reduce dark circles caused by congestion around the eyes. Its anti-inflammatory properties aid in repairing acne scars and wounds while mitigating UV damage. By balancing sebum production and enhancing skin hydration, it refines texture and delivers diverse benefits that contribute to a youthful complexion.
Choose between Rejuran and Rejuran i based on your specific concerns.
At BIANCA CLINIC, we tailor our treatments to each patient's concerns, treatment area, and skin condition, utilizing both standard Rejuran and Rejuran i (Rejuran Eye) specifically designed for the eye area.
The standard Rejuran treatment is primarily applied to the entire face, forehead, neck, and décolleté. It is characterized by its multi-purpose effectiveness in addressing a wide range of concerns, including sagging skin, loss of firmness, enlarged pores, nasolabial folds, forehead wrinkles, and acne scars.
Rejuran i is a formulation specifically designed for the eye area. Its low viscosity allows for easy absorption, making it ideal for treating fine lines around the delicate, thin skin of the eyes and dark circles under the eyes. It can also be used around the mouth, where the skin is equally sensitive.
“Natural rejuvenation without that artificial look
Rejuran (Salmon Injection) helps generate diverse growth factors within skin tissue, creating an environment conducive to cell proliferation. By enhancing the skin's natural healing capacity and fundamentally repairing skin damaged by aging or dryness, this treatment offers natural rejuvenation beyond mere volume enhancement.
Unlike hyaluronic acid injections, which deliver dramatic changes like lifting wrinkles or restoring volume in one session, this treatment works by restoring skin elasticity and firmness. This allows it to address wrinkles and fine lines that are difficult to improve with hyaluronic acid or Botox injections, resulting in a natural finish without that “done-up” look.
Benefits
MERITEasily absorbed into the skin and delivers results from deep within the skin
Salmon-derived polynucleotides are highly compatible with human skin. Their small molecular size allows them to blend easily into the skin, providing immediate stabilization and delivering noticeable effects from deep within the skin.
To enhance natural healing abilities, making it less likely for effects to reverse
This treatment enhances the skin's natural healing ability to promote fundamental repair and regeneration, resulting in effects that are less likely to revert.
Treatable with formulations specifically designed for the eye area
The eye area has thin skin and is a sensitive area prone to irritation. Rejuran i is a specially formulated product designed for gentle application around the delicate eye area.
Recommended Features
RECOMMENDED POINTSCombined injections of Rejuran i and Botox for a translucent, radiant complexion
At BIANCA CLINIC, we offer not only standalone Rejuran i treatments but also combined injections with Botox. The synergistic effect of Rejuran i's ability to restore skin hydration and elasticity, reducing the appearance of wrinkles, combined with Botox's pore-minimizing and sebum-suppressing properties, is key to achieving a translucent, radiant complexion. If you aspire to Korean-style skin, seek enhanced firmness, or are interested in treatments leveraging the best aspects of both Rejuran i and Botox, please feel free to consult with us.
We recommend a total of four injections, administered every 2 to 3 weeks.
This treatment delivers noticeable changes in skin texture after just one session. While individual results may vary, we recommend a total of four treatments spaced 2-3 weeks apart to align with the skin's regeneration cycle and ensure more reliable, noticeable results. Afterward, receiving maintenance treatments approximately every six months helps sustain the effects.
Post-Rejuran Treatment Progress
Immediately after the Rejuran treatment, the injection sites may appear slightly raised like mosquito bites, and the skin may feel bumpy. This typically subsides within a few hours to a day. Additionally, the treated area may swell, and the needle insertion points may develop bruising. While individual responses vary, swelling generally resolves within a few days, and any bruising that appears typically fades within about a week. Please avoid scheduling the treatment immediately before important events; allow approximately 10 days before your appointment.
Makeup may be applied starting the day after your procedure. For those concerned about immediate swelling or bruising, we recommend bringing sunglasses and a mask. Refrain from washing your face for 6 hours after treatment. On the day of your procedure, only showers are permitted. Baths may be taken starting one week later.
Treatment area
TREATMENT AREAForehead, temples, tear troughs, upper eyelids, tip of the nose, bridge of the nose, nasolabial folds, nasolabial lines, lips, chin, jawline, back of the hands, etc.
Treatment Process
CONTENT OF TREATMENTPhysician's examination and counseling
During your consultation, we will thoroughly explain the Rejuran (Salmon Injection) treatment. A physician will examine your skin condition and determine the injection sites. Please share any concerns, questions, or anxieties you may have, in addition to your treatment preferences. We will take the time to provide a thorough examination.
Makeup removal at the injection site
Please remove your makeup and wash your face before your Rejuran treatment. Cleansing products and facial cleansers are provided at our clinic.
Anesthesia
To reduce the pain felt during needle insertion, we apply a topical anesthetic. Our clinic also incorporates anesthetic agents into the Rejuran solution itself, aiming to provide a treatment that minimizes discomfort.
treatment
After allowing time for the topical anesthetic to take effect, the procedure begins. The medication is injected manually in small, precise amounts. The treatment typically takes 15 to 30 minutes. After applying pressure to stop bleeding, the procedure is complete.
Schedule of Charges
PRICE LISTRejuran
| Product Name | 1 time | 3 times | 4 times |
|---|---|---|---|
| Rejuran | ¥77,000 | ¥220,000 | — |
| Rejuran HB | ¥88,000 | ¥250,030 | — |
| Rejuran i ※First-time Botox included | ¥60,500 | — | ¥199,870 |
| Rejuran i + Botox | ¥65,000 | — | — |
Other
| Options | Standard rate |
|---|---|
| Exosome 1V | ¥55,000 |
| Stem Cells 1V | ¥55,000 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
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Frequently Asked Questions About Rejuran (Salmon Injection)
Q&AIs there any downtime?
Rejuran (Salmon Injection) is a treatment with minimal downtime and few side effects. Since the procedure uses syringes, the injection sites may feel lumpy for a few hours post-treatment, but this subsides within hours. Any bruising or swelling that occurs typically resolves within 1 to 2 weeks.
How many sessions of Rejuran (salmon injection) are needed to see results?
Some patients notice changes in skin texture after just one treatment, but we recommend repeating the procedure four times at 2-3 week intervals. After that, we recommend maintenance treatments every few months.
Is there any pain during the treatment?
The injection site and dosage of Rejuran (salmon injection) vary, and some patients may experience pain. At our clinic, we strive to minimize patient anxiety by administering anesthesia prior to treatment. We also offer our unique "Pain-Free Rejuran" procedure, which combines anesthetics in a balanced formulation. Additionally, we use ultra-fine 34-gauge needles to minimize both the pain of the needle insertion and the risk of bruising.
Handmade or machine-made?
Our skin boosters, including Rejuran, are manually administered by our physicians. We carefully inject formulations tailored to each patient's concerns, skin type, and desired outcomes.
What is the difference between Rejuran and Rejuran i?
Rejuran (2cc per vial) is suitable for addressing concerns such as wrinkles, sagging, loss of firmness, enlarged pores, and acne scars across a wide range of areas including the face, neck, and décolletage. Rejuran i (1cc per vial) features a lower viscosity than Rejuran, making it easier to blend. It is effective for treating fine lines around the delicate, thin skin of the eyes and dark circles under the eyes.
What is the difference between Rejuran and hyaluronic acid?
Rejuran differs from hyaluronic acid in that it promotes the regeneration and repair of skin tissue. While hyaluronic acid injections lift wrinkles, adjust facial volume, and bring about dramatic changes, Rejuran promotes natural rejuvenation by restoring skin elasticity and firmness.
Is Rejuran safe?
Salmon-derived polynucleotides are highly biocompatible with the human body. Rejuran has been available in Japan for a relatively long period, with virtually no reports of arterial embolism, other complications, or side effects to date. Consequently, it is gaining attention as a highly safe treatment.
Treatment time: Approximately 15 to 30 minutes
Recommended treatment frequency: Approximately 4 sessions total, every 2 to 3 weeks. After that, maintenance is recommended about once every six months.
Bathing and Facial Cleansing: Showering and facial cleansing are permitted starting the same day. Please avoid bathing on the day of your treatment.
Makeup: Can be applied the next day
Contraindications: The following individuals cannot receive treatment.
・Pregnant women, breastfeeding women, and those who may be pregnant
・Individuals using NSAIDs, immunosuppressants, antiplatelet agents, or anticoagulants
・Individuals with pre-existing conditions such as autoimmune diseases or sarcoidosis
・Individuals with allergies to fish, fish roe, etc.
・Individuals with hypersensitivity to the product's constituent (sodium polynucleotide)
・Individuals who are scheduled to receive treatment with non-resorbable fillers or who have recently undergone such treatment
・Individuals with inflammation, infections, or other conditions deemed ineligible by a physician
※Please consult your physician for details.
Important Notes:
・Pain, itching, or inflammation (redness, swelling, erythema) at the injection site may persist for about one week.
・If bruising or swelling occurs at the injection site, it will subside within about 1 to 2 weeks.
・Avoid prolonged exposure to ultraviolet rays for 1 to 2 weeks after the injection.
Side Effects and Risks: Pain, redness, swelling, bruising, allergic reactions
Regarding the formulation used:
・Rejuran and Rejuran i treatments involve the use of unapproved pharmaceuticals or medical devices within Japan.
・The pharmaceuticals and medical devices used for treatment were imported through personal import procedures under the judgment of our hospital's physicians.
・There are no other domestically approved pharmaceuticals or similar products with the same ingredients and performance.
・Serious side effects may not yet have been identified.
・For information on medicines and other items requiring caution in personal imports, please refer to the following.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
RESERVATION