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2026.07.10
What Is Jubelook Volume (Renisna)? A Clear Explanation of Its Expected Effects, Benefits, and Drawbacks
Driven by the belief of “bringing happiness to more people,” I pursued a career in aesthetic medicine after gaining experience in general internal medicine and emergency surgery, along with overseas training. As an internationally oriented doctor holding a UN English Proficiency Test Special Grade A, I treat a diverse range of patients. My goal is to become a true all-rounder, spanning cosmetic surgery, cosmetic medicine, and cosmetic dermatology. With a deep understanding of global beauty standards, I serve as a Key Opinion Leader (KOL) for TargetCool, NEAUVIA®, and CORETOX®. Known for my gentle manner, I provide accessible consultations in both Japanese and English. I pursue aesthetic medicine that transforms not just appearance, but also enhances overall happiness.

Jubelook Volume (Renisna) is a skin-regenerating skin booster formulation that stimulates your body’s own collagen production while targeting skin depressions and loss of volume.
During consultations, I often receive questions such as, “What kind of results can I expect?” and “Will it end up looking unnaturally swollen?”
To address these concerns, at BIANCA CLINIC, we carefully examine each patient’s skin condition and facial structure before meticulously determining the injection sites and volumes.
In this article, I’ll explain everything—from how the procedure works to the expected results, benefits, and precautions—as clearly as possible from a doctor’s perspective.
What kind of treatment is Jubelook Volume (Renisna)?
Jubelook Volume (Renisna) is an injectable treatment that uses PDLLA to stimulate collagen production and address skin depressions and loss of volume.

An injectable formulation combining PDLLA and non-crosslinked hyaluronic acid
Jubelook Volume is an injectable formulation developed in South Korea and known as “Renisna” outside of South Korea. Its main ingredients are poly-DL-lactic acid (PDLLA) and non-crosslinked hyaluronic acid.
PDLLA is a material that breaks down slowly within the body; when injected into the deeper layers of the skin, it stimulates fibroblasts and promotes collagen production.
Another key feature is its rounded particle structure. Non-crosslinked hyaluronic acid retains moisture to support the skin's hydration and firmness.
Jubelook Volume does not simply fill in depressions with the injected solution; rather, it takes a gradual approach to addressing hollows in the cheeks and temples, the “Gorgon lines,” and nasolabial folds by harnessing the process of collagen regeneration.
The doctor administers the injections while assessing the patient's bone structure and skin condition.
At Bianca Clinic, during the consultation, a doctor personally assesses your facial features, skin thickness, and the location of any hollows to determine the injection sites and the amount of filler to be administered.
VolumeIt’s not simply a matter of using as much as possible. If the depth or amount isn’t right, it can lead to asymmetry, lumps, or unnatural bulges. We place great importance on carefully injecting small amounts into the necessary areas while maintaining the overall balance of the face.
If you'd like to learn more about the treatment method and the areas it can be applied to, please also check out the Jubelook Volume (Renisna) treatment page.
▶Detailed Information on Jubelook Volume (Renisna)
What kind of results can I expect from Jubelook Volume (Renisna)?
By promoting collagen production, it can help minimize the appearance of sunken cheeks, deep wrinkles, and uneven skin texture, while restoring natural firmness and elasticity.
The main changes you can expect are as follows:
- Compensate for a lack of fullness in the cheeks and temples
- Makes nasolabial folds and marionette lines less noticeable
- Improve skin firmness and elasticity
- Smooths out unevenness caused by acne scars and other scars
- Targets enlarged pores and uneven skin texture
Naturally smooth out sunken cheeks and facial hollows
As we age or our weight fluctuates, a loss of volume in the cheeks and temples can make the face look tired or give it a gaunt appearance.
The Jubelook Volume treatment gradually fills in these indentations from the inside by stimulating collagen production. It is often chosen by those who prefer a natural, gradual change over time rather than a sudden transformation of their facial contours.
If you’d like to make a significant change to your appearance or want to see noticeable results immediately after the procedure, another method—such as hyaluronic acid—might be a better fit.
Makes deep wrinkles and lines less noticeable
A loss of volume in the cheeks is one of the causes of deep-looking nasolabial folds, marionette lines, and the "Gorgon lines." By restoring firmness to the surrounding tissues with Jubelook Volume, these lines can be made less noticeable.
However, the causes of wrinkles vary from person to person and include factors such as bone structure, fat, sagging skin, and habitual facial expressions. Since injection treatments alone may not eliminate all wrinkles, we may combine them with device-based treatments or other injection therapies depending on the underlying cause.
It also addresses skin firmness and unevenness
As collagen is produced by PDLLA, skin firmness and elasticity may improve, and unevenness caused by acne scars or other scars, as well as visible pores, may be reduced.
These changes generally occur gradually and typically last for about 1 to 2 years. That said, the onset and duration of the effects vary from person to person depending on skin condition, the injection site, the amount injected, and the number of treatments.
At Bianca Clinic, rather than focusing on a single treatment option, we listen to the root cause of your concerns and the changes you hope to achieve before proposing a treatment plan.
What are the pros and cons of Jubelook Volume (Renisna)?
While this approach allows you to achieve natural, gradual changes in volume, it takes time for the results to become apparent.
Benefits
- Aim for natural changes using your own collagen
- It addresses both volume loss and skin texture
- The effects are expected to last for a relatively long time.
- A doctor can administer precise injections to the areas of concern
Since the appearance changes gradually as collagen is produced, this treatment is ideal for those who want a natural-looking result that is unlikely to be noticed by others.
Another key feature is that it not only fills in depressions but also helps improve skin firmness, elasticity, and texture.
Disadvantages and Risks
- It takes time to feel the effects.
- In some cases, multiple treatment sessions may be necessary.
- Redness, swelling, puffiness, bruising, and hives may occur.
- Possible side effects include pain, infection, allergic reactions, and lumps.
- There may be cases where the desired changes are not achieved.
Immediately after the injection, the area may appear swollen due to the product, fluid, or the procedure itself. This is not the final result. The changes caused by the collagen will continue to develop over time.
Since Jubelook Volume is a treatment that takes advantage of the process by which collagen is gradually produced, you won’t notice the effects immediately after the injection, as you would with hyaluronic acid.
Although the time it takes to reach peak effectiveness varies from person to person, we generally advise that it occurs approximately 3 to 6 months after the procedure.
If you have any concerns about the post-treatment recovery process or whether the treatment is right for you, please consult with a doctor directly during your consultation.
Frequently Asked Questions
We answer common questions about Jubelook Volume, including ingredients, duration, pain, key points to keep in mind during the procedure, and downtime.

Q. What is the main ingredient in this cosmetic injectable?
A. The main ingredients are poly-DL-lactic acid (PDLLA) and non-crosslinked hyaluronic acid. PDLLA promotes collagen production, while non-crosslinked hyaluronic acid helps the skin retain moisture and maintain firmness.
Q. How long does the volume-boosting injection procedure take, and how painful is it?
A. The procedure typically takes about 30 minutes. While we take precautions to minimize pain and bleeding by using a cannula, you may still feel some discomfort during the injection. If you wish, we can consider using anesthesia.
Q. How long do the effects of Jubelook Volume last?
A. On the treatment page, we estimate the results will last approximately 1 to 2 years. However, results and duration may vary depending on the injection site, the amount injected, skin condition, and the number of treatments, so they are not uniform for everyone.
Q. How should I receive the treatment to get the most out of Jubelook Volume?
A. To maintain the desired results, we recommend starting with three injections at one-month intervals, followed by treatments every six months to a year. Even if you feel that “the changes aren’t as noticeable as you expected,” it’s important not to rush and to continue the treatment while monitoring your progress with your doctor.
Q. How long is the downtime after the procedure?
A. Redness, swelling, and puffiness usually subside within a few hours to two days, but bruising may last for one to two weeks. The severity of symptoms and the recovery period vary from person to person.
If you have concerns about the volume of your Jubelook, please consult a doctor.
Jubelook Volume (Renisna) is an injectable treatment that utilizes PDLLA to stimulate collagen production, addressing sunken cheeks, deep wrinkles, acne scars, and other types of scars.
While you can expect natural-looking results that last for a relatively long time, it’s important to understand that it takes some time for the effects to become apparent.
The appropriate injection sites and dosage vary from person to person depending on their bone structure and skin condition. At BIANCA CLINIC, our doctors assess the overall balance of your face and discuss your preferences before recommending a treatment plan.
If you are considering treatment, please feel free to contact us for a consultation.
▶Please see the detailed treatment information for Jubellook Volume (Renisna).
▶Please contact us via the online reservation form.