target cool
TARGET COOL®
Rapid Precision Cooling Medical Device Target Cool®
Achieve pain-free, no-downtime skin treatments
- A drug in the form of ice crystals can be introduced into the dermis without pain.
- CO₂ refrigerant spray alleviates pain and inflammation! Also effective for acne treatment and hair regrowth therapy.
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Implemented in 30 countries worldwide!
TargetCool, a rare aesthetic medical device in Japan
Target Cool is a medical aesthetic device gaining widespread adoption and becoming a trend in 30 countries worldwide, including Korea and Europe. By rapidly injecting low-temperature CO₂ gas, it precisely controls cooling temperature and duration. It is utilized for diverse purposes: instantly forming medications into microscopic ice needles for skin delivery, reducing inflammation through cooling, and improving skin texture via CO₂ infusion.
By swapping out the tip nozzle, the device supports three modes: Boosting mode, which simultaneously injects medication and CO₂ for delivery; Cooling mode, which injects CO₂ refrigerant to alleviate pain and inflammation; and Freezing mode, which destroys diseased tissue using cryogenic CO₂ refrigerant. BIANCA CLINIC offers treatments utilizing the Boosting and Cooling modes.
Boosting Mode supports the introduction of various agents such as Botox, tranexamic acid, and placenta, as well as skin-nurturing formulations like Purelial Silk, Jubellook, and GOURI. Cooling Mode is primarily used for acne treatment and hair growth therapy.
Case Presentation
CASES
Jubellook Injection by Target Cool
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: Immediately after treatment
- Side Effects and Risks
- Redness, swelling, hypothermia, allergies to the formulation used, etc.
- Cost
- ¥66,000
Target Cool-based Pull-Real Injection
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: Immediately after treatment
- Side Effects and Risks
- Redness, swelling, hypothermia, allergies to the formulation used, etc.
- Cost
- ¥66,000
Target Cool Botulinum Toxin Injection
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: Immediately after treatment
- Side Effects and Risks
- Redness, swelling, hypothermia, allergies to the formulation used, etc.
- Cost
- ¥27,500
Target Cool Botulinum Toxin Injection
- Treatment Period and Number of Sessions
- Left: Before treatment / Right: Immediately after treatment
- Side Effects and Risks
- Redness, swelling, hypothermia, allergies to the formulation used, etc.
- Cost
- ¥27,500
Downtime
DOWNTIME【Boosting Mode】
Individuals sensitive to temperature changes may experience redness for 2 to 3 days. Additionally, allergic reactions to the applied medication may occur.
【Cooling Mode】
Individuals sensitive to temperature changes may experience redness for 2 to 3 days. Depending on skin condition and treatment environment, skin may become temporarily overcooled, potentially leading to post-inflammatory hyperpigmentation (PIH).
Recommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSSkin boosters are possible without pain or downtime
Among Target Cool's features, Boosting Mode is particularly noteworthy. This mode employs ice needling technology, which rapidly injects cooling gas while transforming the active ingredient into fine ice particles that penetrate* the skin. This allows the ingredient to reach the dermal layer without degradation, delivering immediate skin quality improvement.
Bianca Clinic offers skin boosters such as Purelial Silk, Juvellook, and GOURI. We also provide customized medication options including Botox, placenta, and tranexamic acid to address your specific concerns.
*The recommended treatment interval varies depending on the medication.
*Penetration... Microparticles of the cooled solution accumulate at high concentrations at the DEJ (dermal-epidermal junction), then penetrate into the dermal layer.
Gentle acne treatment and hair growth promotion therapy in cooling mode
Target Cool's cooling mode is a treatment that effectively calms acne inflammation by precisely controlling refrigerant between -10°C and 5°C and spraying it onto the skin surface. Since the cooling temperature and exposure time can be finely adjusted, a reduction in inflammatory cytokines has been confirmed, and relief from symptoms such as redness and swelling is expected.
Furthermore, cooling stimulation temporarily increases scalp blood flow, promoting follicular metabolism and activating stem cells. This also suppresses the hair loss factor (TGF-β) and increases the hair growth factor (IGF-1), making it effective for improving the hair growth environment and for use alongside thinning hair prevention care.
Additionally, this mode features the non-invasive delivery of CO₂ to the skin. CO₂ possesses antioxidant properties and, through the Bohr effect, enhances oxygen delivery to tissues, leading to increased blood flow, angiogenesis, and reduced inflammation.
*For acne treatment, the recommended treatment interval is once a week.
*Bohr effect... a phenomenon where hemoglobin's ability to bind or release oxygen changes depending on the concentration of oxygen and carbon dioxide in the blood.
Benefits
MERITYou can easily feel the difference in your skin right after the treatment.
Target Cool technology delivers active ingredients directly to the dermis at a depth of approximately 0.3 to 0.4 mm below the skin surface. This depth is shallower than manual injection, making it easier to notice changes in the skin immediately after treatment.
With virtually no downtime concerns
Target Cool does not use needles, eliminating concerns about bruising or needle marks and requiring no downtime. It minimizes stress on the skin, allowing you to undergo treatment with peace of mind.
※Individuals with allergies to medications or temperature-related allergies may experience redness or itching.
Recommended Features
RECOMMENDED POINTSEspecially recommended for those who have avoided skin booster treatments due to concerns about pain
Target Cool's Boosting Mode utilizes ice needling technology with cooling gas to gently deliver skin booster agents into the dermal layer. Since it requires no needles and significantly reduces pain and irritation, this treatment is recommended for those who previously felt apprehensive about injections or concerned about downtime.
The Bohr effect induced by CO₂ introduction is also noteworthy.
Target Cool is also characterized by its ability to non-invasively introduce CO₂ into capillaries through the epidermis and dermis. CO₂ reaching the blood vessels alters the pH within red blood cells, triggering the Bohr effect, which facilitates oxygen release from hemoglobin. This promotes oxygen supply, enhancing cellular metabolism and regenerative capacity, and is expected to suppress inflammation and improve the skin's natural repair capabilities.
Treatment area
TREATMENT AREAFull face
Treatment Process
CONTENT OF TREATMENTPhysician's examination and counseling
During your consultation, we will thoroughly explain the treatment details and examine your skin condition during the physician's examination. Please share any concerns, questions, or anxieties you may have, in addition to your treatment preferences. We will take the time to conduct a thorough examination.
Makeup removal
Before Target Cool treatment, we ask that you remove your makeup and wash your face. Cleansing products and facial cleansers are provided at our clinic.
treatment
We perform the Target Cool treatment on clean skin. Treatment time varies by menu, but the entire process—preparation, treatment, and finishing—takes approximately 30 minutes.
Schedule of Charges
PRICE LISTBoosting Mode
| Product Name / Treatment Site | 1 time | 3 times | 6 times |
|---|---|---|---|
| Botox or Tranexamic Acid or Placenta or SA Serum Infusion Full Face or Neck | ¥27,500 | ¥74,250 | ¥132,000 |
| Pullreal Silk or Jubellook or GOURI Full Face or Neck | ¥66,000 | ¥178,200 | ¥316,800 |
| Exosome Delivery: Full Face or Neck | ¥158,070 | — | — |
| Botox or Tranexamic Acid or Placenta or SA Serum Introduction Back | ¥39,820 | ¥107,470 | ¥191,180 |
Cooling Mode
| Treatment Details | 1 time | 4 times | 8 times |
|---|---|---|---|
| Hair Cool (Hair Regrowth Treatment) | ¥12,100 | ¥43,230 | ¥76,890 |
| Acne Treatment 1 unit | ¥5,500 | — | |
| Acne Treatment (Up to 10 items) | ¥33,000 | — | |
| Unlimited Acne Treatment | ¥55,000 | — |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
Target Cool Frequently Asked Questions
Q&AIs it true that Target Cool treatments are pain-free?
This treatment involves introducing a fine, needle-like medication made of ice that has been instantly cooled in boosting mode. While some individuals may experience a tingling sensation, the use of Target Cool itself is painless.
What is the Bohr effect?
The Bohr effect refers to a state where increased CO₂ in capillaries alters pH within red blood cells, making it easier for hemoglobin to release oxygen. Using Target Cool induces the Bohr effect, promoting greater oxygen release into tissues. This can enhance metabolism and regeneration while offering anti-inflammatory effects.
What are the benefits of ice needling?
The benefit of Ice Needling technology, which instantly transforms active ingredients into microscopic ice needles using CO₂ refrigerant for skin delivery, is its ability to penetrate to the dermis without altering the ingredients. According to the manufacturer's research, the active ingredients penetrate to a depth of 0.3 to 0.4 mm below the skin surface, enabling immediate skin quality improvement. It is also characterized by reduced pain compared to manual injections.
Is the CO₂ refrigerant used in Target Cool safe to touch?
The CO₂ used in Target Cool is food-grade with a purity of 99.91% TP3T, making it safe for skin contact. The cartridge is made of aluminum to prevent internal rust. The dedicated microfilter at the CO₂ cartridge connection point uses a 0.1-micrometer filter to eliminate impurities. Furthermore, a body gel harmless to humans is used during the manufacturing process, ensuring the device can be used with confidence.
Is there any danger in injecting CO₂ refrigerant gas?
TargetCool is operated by physicians who understand the device's structure and have undergone extensive training. The device is designed with patient safety in mind, and once the CO₂ cartridge is attached, it forms a sealed state with no gas leakage.
Is there anything I should be aware of before the treatment?
Please keep the treatment area clean. Consult your physician if you have undergone other cosmetic procedures on your skin, have a medical history, or are taking any medications. Additionally, if you are pregnant, may be pregnant, or have any specific health-related conditions, please be sure to inform your physician before treatment.
Are there any precautions to take after the treatment?
For 3 to 4 hours after treatment, avoid actions that may irritate the skin, such as rubbing the treated area or exposing it to direct sunlight. Also, refrain from activities that increase blood flow immediately after treatment, including strenuous exercise, saunas, bathing, and excessive alcohol consumption.
Treatment Details: Target Cool
Estimated Treatment Period and Number of Sessions:
・The recommended treatment interval varies depending on the medication.
・For acne treatment, approximately once a week is recommended.
Side Effects and Risks: Redness, swelling, hypothermia, allergies to the medication used, etc.
Treatment Using Unapproved Medical Devices, Unapproved Pharmaceuticals, and Other Unapproved Products
・This treatment involves the use of drugs not approved in Japan or treatments that differ from their approved indications.
Medical Device Approval Number: FDA 510(k) K230599, CE MDD: 2021-MDD QS-007, MFDS 21-69
・Medicines and medical devices used for treatment are imported through personal import procedures under the judgment of our clinic's physicians. For information on medicines and other items requiring caution in personal import, please refer to the following.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・Except for products that have obtained pharmaceutical approval, there are no other domestically approved pharmaceuticals or medical devices with the same ingredients or performance.
・Information regarding safety and other matters in other countries
－Significant risks may not have been identified.
・In the unlikely event of serious side effects, this product is not covered by the national pharmaceutical adverse reaction victim relief system.
RESERVATION