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2026.09.12
Who Is DaxiFi Right For? An Explanation of Its Pros and Cons and Its Approximately 6-Month Duration
My journey into aesthetic medicine stems from a desire to help enrich and beautify lives beyond simply treating illness. My specialties include hyaluronic acid, Botox, and thread lifts. I provide treatments that enhance each individual's unique qualities and bring out an elegant, natural beauty. For concerns around the eyes that are difficult to improve with dermatology alone, I also perform surgical procedures. By integrating dermatology and surgery, I holistically balance the entire face. With three periods of overseas study, I am also able to provide consultations in English.
"I'd like to continue getting Botox injections, but I wish I could space them out a little more."
Some people who receive Botox injections on a regular basis may feel this way.
DAXXIFY® is a type A botulinum toxin product characterized by its long-lasting effects.
In a Phase III clinical trial targeting expression lines between the eyebrows, it was reported that the period during which the lines were “absent or mild” lasted approximately 24 weeks, or about 6 months.
At BIANCA CLINIC, we believe that when choosing a botulinum toxin product, it is important to consider not only the duration of the effects but also the desired outcome and how much natural facial expression you wish to preserve.
In this article, we’ll explain who Dakshifai is best suited for, including its pros and cons.
Who is Dakshifai best suited for?
Dakshify may be a good fit for those who prioritize the duration of the effects or who want to space out their treatments as much as possible.
Daxifai is one of the options worth considering for people who:
- For those who prioritize the duration of effect from botulinum toxin injections
- For those who want to keep the frequency of regular treatments to a minimum
- Those who have already had botulinum toxin injections and have an idea of the desired results
- For those who want to choose products based on their ingredients and formulation
Benefits of Daxify | A duration of approximately 6 months has been reported
A particularly important point is the duration.
Clinical trials have reported that the period during which "no wrinkles or only mild wrinkles" persisted lasted approximately 24 weeks*.1。
However, this is the median, and not everyone will remain in the same condition for six months.
Still, for those who prioritize treatment duration when choosing a medication, this may be one reason to consider Daxiify.
Benefits of Daxify | Features Our Proprietary Peptide Technology “RTP004”
Another key feature of Daxify is its formulation design, which utilizes the proprietary synthetic peptide “RTP004.”
According to the FDA review documents, DAXXIFY® uses RTP004 as an additive, contains no human serum albumin, and does not contain any human- or animal-derived ingredients.*2。
When choosing a botulinum toxin product, one of the factors to consider—besides “how long the effects last”—is the composition of the product.
At Bianca Clinic, we place great importance on developing treatment plans that take into account each individual’s facial muscle movements and desired results, rather than simply choosing a product based on its duration of effect alone.
Who might not be a good fit for Daksify?
For those who want to try it out for a short period or make frequent adjustments to the final look, a long-lasting formula might not be the right choice.
A longer duration isn’t necessarily a benefit for everyone.
For example, for those who are anxious about the results of their first botulinum toxin injection, or those who want to start by trying out the effects over a short period of time, a long-lasting effect may not align with their expectations.
Additionally, for those who want to make frequent adjustments to their appearance while monitoring facial movements, it may be better to consider other formulations as well, rather than choosing Dakshify based solely on its duration of effect.
Just because a treatment lasts a long time doesn’t necessarily mean it’s right for you. It’s important to consider how much of your natural facial expression you want to preserve and how often you’d like to undergo the procedure before making your choice.
If the results last about 6 months, is it enough to have the treatment twice a year?
Although data shows that the effects of DAXXIFY® last for about 6 months, the duration varies from person to person, so it cannot be said definitively that twice a year is sufficient.
You might be thinking, “If the effects last about six months, wouldn’t it be enough to get it done twice a year?”
However, the figure of approximately 24 weeks from the clinical trial represents the median duration during which glabellar lines remained “absent or mild.”
The actual duration varies from person to person and depends on factors such as the treatment area and muscle movement.
Therefore, rather than making blanket statements such as “it will definitely last six months” or “twice a year is enough,” it is necessary to determine the timing of treatment based on each individual’s condition.
Frequently Asked Questions
In the following section, we'll provide a concise explanation of common questions about Daxify.
Q. When does Daxifai start to take effect?
A. It is generally believed that changes from Daxify begin to appear within about 2 to 3 days*3.
However, the way the effects manifest varies from person to person.
Q. Is the dosage of Daxify the same as that of Botox?
A. No, you cannot simply convert the "units (U)" for each formulation on a one-to-one basis.
Since the required dosage varies depending on the formulation, it is not appropriate to judge whether it is high or low based solely on the number of units.
Q. Is Dakshify different from fillers like hyaluronic acid?
A. Yes, they are different. Daxify is a type A botulinum toxin product that acts on the signals transmitted from nerves to muscles.
Fillers such as hyaluronic acid are procedures designed to restore volume to the tissue, and they work in different ways.
Q. What is the generic name for Daxify?
A. The generic name for DAXXIFY® is “daxibotulinumtoxinA-lanm.” It is an injectable formulation containing botulinum toxin type A as its active ingredient.
Q. Is Dakxify approved in Japan?
A. DAXXIFY® is approved by the FDA in the United States, but it is not an approved drug in Japan.
It is important to check the approval status overseas and the approval status in Japan separately.
Daxify approaches Botox injections by asking, “Do you want the results to last longer?”
DAXXIFY® is a type A botulinum toxin product characterized by clinical data showing a duration of action of approximately 24 weeks and a proprietary formulation design based on RTP004.
While this is a good option for those who want to limit the frequency of treatments or prioritize long-lasting results, it may not necessarily be the best fit for those who want to try it out for a short period or make frequent adjustments to the look.
Instead of deciding based solely on the product name, consider what works best for you by taking into account factors such as "how long you want the effect to last" and "what kind of look you want to achieve."
At BIANCA CLINIC, we take into account not only the characteristics of the formulation but also the movement of facial muscles and your desired results as we develop a botulinum toxin injection plan tailored to each individual.
*2:FDA Multidisciplinary Review and Evaluation: DaxibotulinumtoxinA for Injection
