Mesona J (Mesoporation)
MESONA-J
Deliver medication deep into the skin without causing pain
Care for pores, sagging skin, dark spots, and wrinkles
- Using the domestically produced Mesona J transdermal delivery device to achieve ideal skin without pain or downtime
- Mesoporation technology delivers high-molecular-weight components into the dermal layer.
- You'll feel the effects from the very first session, and the longer you continue the treatments, the longer the results will last.
Guided by the philosophy of "Japanese-quality aesthetic medicine recognized worldwide," we oversee specialized doctor teams across plastic surgery, aesthetic dermatology, aesthetic internal medicine, aesthetic gynecology, regenerative medicine, and permanent makeup. Beyond the clinic, we serve as leaders in roles such as Representative Director of Creation Labo, Producer of Cutting Edge, and Director of the Japan Society of Aesthetic Internal Medicine. Our goal is to deliver not just satisfaction, but profound delight. A game changer in the aesthetic medicine field, proposing Lifestyle Beauty that transcends the boundaries of traditional cosmetic treatments.
Treatment using our clinic's proprietary, expert techniques: BIANCA METHODS
At BIANCA CLINIC, we have established the "BIANCA METHODS" as our unique, highly skilled techniques to consistently provide patients with high-quality treatments, including Mesona J. BIANCA METHODS sets strict standards for all treatments based on effectiveness, friction risk, and quality, and we continuously refine them with each new discovery.
Mesona J training is conducted repeatedly based on the BIANCA METHODS, and only nurses who pass the test are permitted to perform treatments on actual patients. Training involves thorough instruction on every step, starting with how to drape towels over the face and décolletage, through to how to apply Mesona J devices, how to place packs after treatment, and how to apply cream. Dermatologists sometimes participate in the training, providing feedback to help practitioners further enhance their skills.
Case Presentation
CASES
MESONA-J (MESONA-J/Mesoporation)
- Treatment Period and Number of Sessions
- Mesona J 1 session
- Side Effects and Risks
- Redness or stinging may occur depending on the medication used and individual differences.
- Cost
- Mesona J THE PINK Full Face + Neck ¥30,030 per session
MESONA-J (MESONA-J/Mesoporation)
- Treatment Period and Number of Sessions
- Mesona J 1 session
- Side Effects and Risks
- Redness or stinging may occur depending on the medication used and individual differences.
- Cost
- Mesona J THE WHITE Full Face (excluding lips) ¥17,930 per session
Downtime
DOWNTIME
Recommended for people like this
RECOMMENDED FOR:Features
CHARACTERISTICSWhat is Mesona J?
Mesona J is the world's first transdermal delivery device exclusively for medical institutions to meet stringent quality standards required for medical devices (JIS standards, EMC testing, etc.). Furthermore, Mesona J is a domestically produced transdermal delivery device of higher quality and performance that fully incorporates all the functions of the renowned Italian-made "Mesactis," also an exclusive transdermal delivery device for medical institutions.
Unlike iontophoresis or ultrasonic delivery devices, Mesona J features mesoporation technology utilizing electroporation. Electroporation is a technique that applies specialized electrical pulses to the skin, creating microscopic gaps in the skin cell membranes. This method allows multiple non-ionized ingredients and high-molecular-weight active ingredients—substances that cannot penetrate through topical application alone—to be painlessly delivered simultaneously deep into the dermis layer of the skin.
Penetration power is 70 times that of an iontophoresis device and 300 times that of regular application.
Mesona J delivers active ingredients directly to the dermis without damaging the skin, acting directly on cells to produce effects comparable to injection methods. Through Mesona J's mesoporation technology, the penetration power of beneficial ingredients into the skin is said to increase approximately 300 times compared to regular application and about 70 times compared to using an iontophoresis device.
Mesona J treatment involves two steps. First, electroporation is performed using a pen-shaped probe to create pathways for delivering active ingredients into the dermis. Next, a roller-shaped probe is applied to the skin, using electrostatic repulsion, electroosmosis, and physical pressure to introduce active ingredients into the dermis without causing skin damage or pain. Any small gaps created in the cell membranes close immediately, so there is no need for concern.
A combination of eight beneficial ingredients is used as the introduction agent.
At our clinic, we combine appropriate active ingredients from the following 8 types based on your skin concerns and preferences. We then use either the pink THE PINK or white THE WHITE introduction agent with Mesona J. Please consult with our physician for details.
1) Vitamin C Derivative: Effective for wrinkles, dark spots, and anti-aging care. Boosts collagen production for firmer, more translucent skin.
2) Tranexamic acid: Particularly effective for melasma. It may also help suppress inflammation.
3) Arbutin: Expected to improve post-inflammatory hyperpigmentation and provide whitening effects.
4) Argireline: Effective for wrinkles. Also known as "topical Botox."
5) Hyaluronic Acid: Effective for anti-aging care and enhancing skin hydration. It refines skin texture and promotes firm, radiant skin.
6) Vitamin A: Effective for enlarged pores, acne, and anti-aging care. Prevents photoaging and promotes firm, resilient skin.
7) Vitamin B12: Useful for redness of the face and atopic dermatitis
8) Vitamin B6: Supports skin turnover and helps eliminate dead skin cells and clogged pores.
Benefits
MERITYou can feel the effects immediately after treatment
Immediately after treatment, you can experience numerous benefits for skin concerns like dark spots, melasma, fine wrinkles, acne, and redness, as well as for goals such as brightening, improving skin texture, enhancing firmness, and boosting hydration.
Virtually no pain or downtime during treatment
Mesona J causes minimal discomfort and downtime during treatment, making it suitable even before important events or during therapeutic* procedures.
*Therapeutic … A 3-4 month intensive skin improvement program using ZeoSkin Health products from Doctors Cosme.
Makeup can be applied immediately after the treatment.
Mesona J causes minimal skin irritation and rarely results in swelling or redness after treatment, so makeup can be applied immediately afterward without issue.
Recommended Features
RECOMMENDED POINTSThe Difference Between Mesona J and Ion Introduction or CareSys
Mesona J utilizes electroporation technology to deliver even high-molecular-weight ingredients into the skin, whereas iontophoresis devices cannot introduce large-molecular-weight components. Furthermore, Mesona J can deliver agents into the dermal layer, while iontophoresis devices only allow agents to penetrate the epidermal layer.
Next, regarding the difference between Mesona J and CareCis. Both utilize electroporation technology to deliver agents into the dermal layer. However, CareCis achieves approximately 20 times the penetration rate compared to iontophoresis devices, while Mesona J achieves approximately 70 times the rate. Additionally, Mesona J features a wider variety of delivery agents and allows for customized agent selection based on specific skin concerns and treatment areas.
The Difference Between Mesona J and HydraFacial (Skin Booster)
Mesona J, also known as "needle-free hydrating injections," involves using an automated injector with an ultra-fine needle to gently lift the skin while delivering beneficial ingredients into the shallow dermal layer. At BIANCA CLINIC, we utilize the "BellaVita" hydrating injection system, designed with low noise and high vacuum pressure to minimize discomfort and bleeding.
During the HydraFacial treatment, topical anesthesia is applied using an anesthetic cream, and we provide regular reassurance throughout the procedure to minimize discomfort. Since HydraFacial involves direct injection into the skin, it is considered to have a higher delivery efficiency than Mesona J.
However, for those who are sensitive to anesthetic cream, dislike needles, or wish to minimize skin damage, we recommend Mesona J—a treatment that requires no anesthetic cream or needles, with virtually no pain or downtime.
Important Notes for Mesona J
There are virtually no disadvantages such as side effects or risks associated with Mesona J treatment. While allergic reactions to the introduced medication are possible in rare cases, the introduced medication used at our clinic rarely causes allergic reactions.
Mesona J delivers electrical currents to the skin, so during treatment you may experience a mild tingling sensation. Treatments near the mouth may cause a metallic taste, and treatments near the eyes may produce flashes of light. However, there is no significant pain or discomfort beyond this, and some patients even fall asleep during Mesona J treatments. However, in rare cases, redness or dryness may appear on the treated area due to the electrical stimulation or friction from the probe. If this occurs, please contact our clinic immediately.
Please refrain from shaving your face 2-3 days prior to treatment and avoid peel-off masks or massages the day before. For one week after treatment, avoid using scrub products and ensure thorough moisturizing care and UV protection.
Video
MOVIETreatment area
TREATMENT AREAFace, Neck, Back: We recommend a treatment interval of once a week.
Treatment Process
CONTENT OF TREATMENTCleansing & Facial Wash
Patients will wash their face and remove makeup themselves. If any makeup, cleanser, or makeup remover remains, it may penetrate deep into the skin during the Mesona J treatment, so please rinse thoroughly. To ensure a smooth treatment process, please come to your appointment wearing no makeup or only light makeup on the day of your treatment.
Physician's examination and counseling
During your consultation, we will thoroughly assess your skin condition and concerns, recommend suitable treatment solutions tailored to your skin type and issues, and adjust your treatment schedule accordingly. We will explain the procedure details, expected results, and precautions. Please feel free to ask any questions or voice any concerns you may have.
treatment
Before treatment, please remove any metal items in contact with your skin, such as watches and jewelry. The practitioner will wipe away any remaining makeup and sebum, then apply the introduction agent to your skin. First, an electric pulse is applied using a pen-type probe, followed by the introduction of the agent using a roller-type probe.
Soothe with a pack, finish with a cream
After the treatment, we apply a mask and cream for a soothing and moisturizing treatment to thoroughly condition your skin. You may apply makeup immediately afterward, so please use the makeup room.
Schedule of Charges
PRICE LISTPINK
| Part | 1 time | 5 times | 10 times | Options |
|---|---|---|---|---|
| Full Face + Neck | ¥30,030 | 120,120 yen | ¥210,210 | |
| SA Serum ※Drug Addition Option | ¥2,420 |
WHITE
| Part | 1 time | 5 times | 10 times | Options |
|---|---|---|---|---|
| Full face (excluding lips) | ¥17,930 | ¥80,740 | ¥143,440 | |
| Lip Hyaluronic Acid ※Drug Addition Option | ¥2,420 | |||
| Add neck | ¥5,500 |
Mesona SA
| Part | 1 time | 5 times | 10 times | Options |
|---|---|---|---|---|
| Full face | ¥19,800 | ¥89,100 | ¥158,400 | |
| High-concentration glutathione ※Drug-addition option | ¥2,420 | |||
| Hyaluronic Acid ※Optional drug additive | ¥2,420 | |||
| Add neck | ¥5,500 |
Pigmentation Care
| Part | 1 time | 5 times | 10 times |
|---|---|---|---|
| knees, elbows, armpits, etc. | ¥17,930 | ¥80,740 | ¥143,440 |
Mesona J
| Part | 1 time | 3 times | 6 times |
|---|---|---|---|
| back | ¥43,780 | ¥118,250 | ¥210,100 |
| buttocks | ¥43,780 | ¥118,250 | ¥210,100 |
Lifestyle Beautyis
proposed.
Our goal is to move you beyond satisfaction.
Responding to the desire for greater beauty and health,
What can we do for the well-being of our patients?
Providing total beauty to make your life shine,
That is our policy.
Go to BIANCA and you'll find a smile.
That's the kind of place we're aiming for.
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Frequently Asked Questions About Mesona J (Mesoporation)
Q&ADoes Mesona J cause pain during treatment?
Mesona J requires no needles, so there is virtually no pain and no need for anesthetic cream. Since it uses electricity, you may feel a slight tingling sensation. Furthermore, there is no downtime such as swelling, redness, or scarring after the procedure.
Can you advise me on which areas to treat with Mesona J?
Yes, of course. You can discuss your options during your consultation and decide on the treatment area on the day of your appointment. If you have a specific area in mind from the start, letting us know when you make your reservation will help things go more smoothly.
Can I apply makeup as usual after a Mesona J treatment?
Yes, you may apply makeup immediately after the treatment. In addition to makeup, you may also wash your face, bathe, and exercise as usual.
When can I start feeling the effects of Mesona J?
You can often see noticeable before-and-after differences in tone-up, skin firmness, and radiance immediately after the first treatment. For other concerns, we recommend continuing with multiple sessions. Please ask your doctor how many sessions are typically needed.
How often should Mesona J treatments be scheduled?
Mesona J tends to have a longer duration with each subsequent treatment, so BIANCA CLINIC recommends weekly sessions. We can also propose a schedule at a frequency that suits your needs without causing undue strain. Please consult your physician for details.
How long does the Mesona J treatment take?
The treatment time for the entire face is approximately 15 minutes, though this varies depending on the area being treated. Including pre-treatment and post-treatment procedures, the total time required is about 30 minutes to 1 hour.
Are there times when Mesona J treatments are not available?
Yes, we do. The following individuals are unable to receive Mesona J treatment. For details, please contact BIANCA CLINIC.
・Individuals with allergies to the medications used
・Individuals with pacemakers, implantable cardioverter defibrillators, metal plates, or gold sutures in their bodies
・重度の心疾患・糖尿病の方
・治療部位に大きな瘢痕組織・感染性の皮膚疾患がある方
・Pregnant women and nursing mothers
メソナJはほかの施術と併用できますか？
はい、メソナJはレーザーやダーマペン、ハイドラフェイシャルなどと併用することが可能です。どの施術と組み合わせるかは肌状態や肌悩みによって異なります。詳しくは医師へお尋ねください。
メソナJはBIANCA CLINICのどちらの院で受けられますか？
メソナJはBIANCA CLINIC銀座院と表参道院のどちらでも施術をしております。予約状況についてはいつでもお気軽にお問い合わせください。
施術名：メソナJ（MESONA-J／メソポレーション）
施術にかかる時間：30分～1時間程度 ※カウンセリングや施術内容によって時間は異なります。
施術回数の目安 ：週に1回 ※治療内容によっても異なります。
施術期間の目安：4～6ヶ月程度
Bathing and facial cleansing: Permitted starting the day of treatment
メイク：施術後当日より可能 ※施術後は、メイクをしてお帰りいただけます。
禁忌：次の方は、施術をお受けいただけません。
・妊娠中の場合
・心臓ペースメーカーを装着している場合
・電子機械、金属などの人工器官を内蔵している場合
・心臓病の場合
・てんかんの既往症をお持ちの場合
※Please consult your physician for details.
注意事項：次の方は施術を受ける場合、事前に慎重な検討が必要です。
・対象部位に極度の肌荒れがある場合
・アトピー性皮膚炎の場合
・炎症がある場合
・治療途中の創傷がある場合
・金属・化粧品・薬剤・食物などにアレルギーがある場合
・体調が悪い場合は、回復して数日経ってから施術をお受けください。
・金属・化粧品・薬剤・食物などにアレルギーがある方は、事前にお申し出ください。必要に応じてテストなどを行い、慎重に検討します。
・施術前に、化粧成分を確実に落とすため、しっかりと洗顔を行っていただきます。
・施術中はネックレス・時計・ピアス・ブレスレット・指輪など肌に触れている金属類はすべて外していただきます。
※Please consult your physician for details.
Side Effects and Risks:
使用する薬剤によるアレルギー反応（発赤、熱感、かゆみ、腫れ、発疹）、ピリピリとした刺激、閃光など
Regarding the equipment used:
・メソナJの治療には、国内未承認医薬品または医療機器を用いた施術が含まれます。
・治療に用いる医薬品および医療機器は、当クリニックの医師の判断のもと、株式会社SeleneMedicalより個人購入手続きを行ったものです。個人購入における注意すべき医薬品等に関する情報は、下記をご参照ください。
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・There are no other domestically approved pharmaceuticals with the same ingredients or performance.
・国内における安全性等に係る情報
以下の認証を取得しています。
安全規格JIS-T 0601-1（IEC60601-1:2005）
電磁両立性（EMC）IEC60601-1-2:ed3
RESERVATION