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2026.06.30
What Are the Signs That Male Menopause Is Ending? A Doctor Explains Symptom Changes and Testosterone Therapy

"I get tired more easily than before," "I can't seem to get motivated," "I tend to feel down."
When these symptoms persist, it’s not uncommon for men to feel anxious, wondering, “Could this be male menopause?” or “When will this end?”
Actually, “Signs That Male Menopause Is Ending" is a frequently searched keyword. However, male menopause does not necessarily end after a fixed period of time, as female menopause does, and its course varies depending on the cause.
Male menopause (LOH syndrome) refers to symptoms caused by a decline in the male hormone (testosterone) due to aging, stress, and other factors. With proper diagnosis and treatment, many men experience relief from their symptoms, and an improvement in their quality of life (QOL) can be expected.
In this article,Signs That Male Menopause Is Improving, How to Recognize Symptoms, and Male Hormone Injections (Testosterone Undecanoate)Dr. Yoko Maeda, a board-certified specialist with the American Academy of Anti-Aging Medicine, provides an easy-to-understand explanation.
What Is Male Menopause? Is It a Condition That Eventually Goes Away?
Male menopause (LOH syndrome) is a syndrome caused by a decline in testosterone, a male hormone.
In addition to aging, chronic stress, lack of sleep, obesity, lack of exercise, and lifestyle-related diseases are also major factors contributing to these symptoms.
Unlike menopause in women, there is no clear dividing line such as “menopause,” so it is often difficult to tell when it “ends.”
On the other hand, it is not uncommon for symptoms to improve through treatment of the underlying cause or lifestyle changes.
Signs That Male Menopause Is Coming to an End
① You'll wake up feeling better in the morning
Male hormones also play a role in sleep quality.
If we make improvements,
- Many people report that they wake up feeling refreshed in the morning, experience less drowsiness during the day, and feel less fatigued at the end of the day.
However, since there may be underlying conditions such as sleep apnea, you should avoid self-diagnosis.
② Motivation and concentration return
"Everything felt like a hassle."
Typical signs of improvement include being able to enjoy hobbies again, regaining the ability to concentrate on work, and feeling more motivated.
In addition to alleviating feelings of depression, it may also have a positive effect on cognitive function and judgment.
③ Improvement in Sexual Function
Testosterone also plays a significant role in sexual function.
As your condition improves, you may notice changes such as a return of sexual desire, more frequent morning erections, and improved erectile function.
On the other hand, if there are other underlying causes, such as diabetes or vascular disorders, treatment with male hormones alone may not be sufficient to resolve the issue.
④ Muscle strength and stamina return
Male hormones are also important for maintaining muscle mass.
Some people find that combining treatment with exercise makes climbing stairs easier, helps them see results from strength training more quickly, and makes them less prone to fatigue.
Consult a specialist now.
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Reasons Why Male Menopause Symptoms Don't Improve
If there is no improvement, other conditions besides low testosterone—such as sleep disorders, thyroid disorders, depression, diabetes, and anemia—may be contributing factors.
At our clinic, we don’t just rely on a medical interview—we also perform blood tests to confirm whether low testosterone levels are truly the cause.
[Internal Link: Male Hormone Testing]
What Are Undecanoic Acid Testosterone Injections?
Testosterone undecanoate is a long-acting form of testosterone replacement therapy.
It is characterized by a longer dosing interval than typical short-acting formulations and tends to maintain relatively stable blood levels.
Once blood levels stabilize, symptoms also stabilize, which reduces the likelihood of symptom fluctuations and improves quality of life.
In addition, since undecanoate testosterone is administered via injection approximately once every 3 to 4 months, it offers the advantage of being more accessible to patients who are busy and find it difficult to make time to visit the clinic, compared to the typical schedule of injections every 2 to 4 weeks.
We will determine the appropriate course of treatment based on the doctor's examination and blood test results, and proceed with treatment while conducting regular follow-ups.
Expected changes include reduced fatigue, increased motivation, improved sexual function, and maintenance of muscle strength; however, results may vary from person to person.
Features of Our Clinic's Testosterone Therapy
At our clinic, we do not base our decisions solely on testosterone levels; instead, we conduct a comprehensive evaluation of symptoms, perform necessary blood tests, provide support for lifestyle improvements, and offer long-term management using undecanoic acid testosterone.
We don’t just administer injections; we also consider “why testosterone levels have declined” and strive to provide personalized care for each patient.
Comment from a Specialist
While male menopause is often dismissed as “just a natural part of aging,” there are actually quite a few symptoms that can be improved with proper diagnosis.
If you experience persistent fatigue, a loss of motivation, or changes in sexual function, we recommend undergoing a medical examination that includes testing for male hormones.
— Dr. Yoko Maeda
Board-Certified Anti-Aging Physician by the American Academy of Anti-Aging Medicine
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If you think you might be experiencing male menopause
Why not have your testosterone levels checked and consult a specialist?
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Frequently Asked Questions (FAQ)
Q1 Does male menopause end on its own?
It depends on the cause and lifestyle habits. While some people recover on their own, others may require treatment.
Q2 How many male hormone injections are typically needed?
This depends on your symptoms and test results. Your doctor will propose a treatment plan while monitoring your progress.
Q3 Can anyone get tested for undecanoic acid testosterone?
Because conditions such as prostate disorders require careful assessment of suitability, we provide guidance only after conducting a medical examination and tests.
Q4 When can I expect to see results?
The time it takes to notice a change varies from person to person. Some people may take anywhere from a few weeks to a few months to notice a change.
Q5 Are there any side effects?
We will conduct treatment with safety in mind, while performing regular blood tests to monitor for increases in red blood cell count and any effects on the prostate.
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